solasodine-3924 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the solasodine-3924 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
ANK1 ankyrin 1, erythrocytic
ARHGAP1 Rho GTPase activating protein 1
ASIC2 acid sensing (proton gated) ion channel 2
C10ORF12 chromosome 10 open reading frame 12
C21ORF2 chromosome 21 open reading frame 2
CCL7 chemokine (C-C motif) ligand 7
CD6 CD6 molecule
CDC25C cell division cycle 25C
CDSN corneodesmosin
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CTRC chymotrypsin C (caldecrin)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DGCR8 DGCR8 microprocessor complex subunit
ELN elastin
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPS8L3 EPS8-like 3
ERCC2 excision repair cross-complementation group 2
EXTL1 exostosin-like glycosyltransferase 1
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF16 fibroblast growth factor 16
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
FRMD8 FERM domain containing 8
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GP2 glycoprotein 2 (zymogen granule membrane)
GRIP2 glutamate receptor interacting protein 2
GRM1 glutamate receptor, metabotropic 1
GSTP1 glutathione S-transferase pi 1
HDAC7 histone deacetylase 7
IGLJ3 immunoglobulin lambda joining 3
IGSF6 immunoglobulin superfamily, member 6
IL25 interleukin 25
KHK ketohexokinase (fructokinase)
KIAA0226L KIAA0226-like
KIF25 kinesin family member 25
KLK8 kallikrein-related peptidase 8
LAMC3 laminin, gamma 3
LGALS8 lectin, galactoside-binding, soluble, 8
LIME1 Lck interacting transmembrane adaptor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRP4 low density lipoprotein receptor-related protein 4
LY86 lymphocyte antigen 86
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAL mal, T-cell differentiation protein
MAP2K7 mitogen-activated protein kinase kinase 7
MED25 mediator complex subunit 25
MFSD7 major facilitator superfamily domain containing 7
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPPA natriuretic peptide A
NR1I3 nuclear receptor subfamily 1, group I, member 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NXF2 nuclear RNA export factor 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PDGFC platelet derived growth factor C
POU3F4 POU class 3 homeobox 4
PPARD peroxisome proliferator-activated receptor delta
PQBP1 polyglutamine binding protein 1
PRDM12 PR domain containing 12
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RECQL5 RecQ protein-like 5
RHAG Rh-associated glycoprotein
RORC RAR-related orphan receptor C
RPL23AP53 ribosomal protein L23a pseudogene 53
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1 runt-related transcription factor 1
SFTPB surfactant protein B
SPN sialophorin
SSX1 synovial sarcoma, X breakpoint 1
ST7L suppression of tumorigenicity 7 like
STOML1 stomatin (EPB72)-like 1
SYCP1 synaptonemal complex protein 1
TBC1D2 TBC1 domain family, member 2
TBCD tubulin folding cofactor D
TBKBP1 TBK1 binding protein 1
THAP3 THAP domain containing, apoptosis associated protein 3
TMEM40 transmembrane protein 40
TRAPPC9 trafficking protein particle complex 9
TRH thyrotropin-releasing hormone
TRIM29 tripartite motif containing 29
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ULK4 unc-51 like kinase 4
ZNF175 zinc finger protein 175
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ACTL8 actin-like 8
ADTRP androgen-dependent TFPI-regulating protein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALPK1 alpha-kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATAT1 alpha tubulin acetyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B9D2 B9 protein domain 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF79 chromosome 14 open reading frame 79
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX8 chromobox homolog 8
CCDC94 coiled-coil domain containing 94
CD34 CD34 molecule
CDHR2 cadherin-related family member 2
CDK18 cyclin-dependent kinase 18
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CIDEB cell death-inducing DFFA-like effector b
CLEC4E C-type lectin domain family 4, member E
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNGB3 cyclic nucleotide gated channel beta 3
CNTN1 contactin 1
CSF1R colony stimulating factor 1 receptor
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP13 dual specificity phosphatase 13
EDN1 endothelin 1
FAM155B family with sequence similarity 155, member B
FAM198B family with sequence similarity 198, member B
FAM46C family with sequence similarity 46, member C
FBXL6 F-box and leucine-rich repeat protein 6
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXI1 forkhead box I1
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GEM GTP binding protein overexpressed in skeletal muscle
GK3P glycerol kinase 3 pseudogene
GPR143 G protein-coupled receptor 143
HIST1H1D histone cluster 1, H1d
HIST1H4F histone cluster 1, H4f
IFI6 interferon, alpha-inducible protein 6
IFNA17 interferon, alpha 17
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC61 leucine rich repeat containing 61
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MAP3K2 mitogen-activated protein kinase kinase kinase 2
NOTCH4 notch 4
NPFFR1 neuropeptide FF receptor 1
NSUN6 NOP2/Sun domain family, member 6
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSMR oncostatin M receptor
PCDHA6 protocadherin alpha 6
PDE12 phosphodiesterase 12
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC1 placenta-specific 1
PORCN porcupine homolog (Drosophila)
PSG4 pregnancy specific beta-1-glycoprotein 4
PTK6 protein tyrosine kinase 6
PYHIN1 pyrin and HIN domain family, member 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF208 ring finger protein 208
RPL10L ribosomal protein L10-like
SAA4 serum amyloid A4, constitutive
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLN sarcolipin
STK16 serine/threonine kinase 16
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLN1 talin 1
TM4SF4 transmembrane 4 L six family member 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
UBTD1 ubiquitin domain containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZNF134 zinc finger protein 134
ZNF329 zinc finger protein 329
ZNF362 zinc finger protein 362
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZNF532 zinc finger protein 532
ZNF747 zinc finger protein 747
ZSWIM1 zinc finger, SWIM-type containing 1