solanine-4087 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the solanine-4087 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AIM1L absent in melanoma 1-like
AKAP6 A kinase (PRKA) anchor protein 6
ANTXR1 anthrax toxin receptor 1
BBC3 BCL2 binding component 3
BLZF1 basic leucine zipper nuclear factor 1
C22ORF24 chromosome 22 open reading frame 24
CD244 CD244 molecule, natural killer cell receptor 2B4
CEMP1 cementum protein 1
CES3 carboxylesterase 3
CIITA class II, major histocompatibility complex, transactivator
CLCN7 chloride channel, voltage-sensitive 7
CNTN1 contactin 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYTH3 cytohesin 3
DIAPH2 diaphanous-related formin 2
DIO2 deiodinase, iodothyronine, type II
DLX2 distal-less homeobox 2
DMBT1 deleted in malignant brain tumors 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
EGR1 early growth response 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESRRG estrogen-related receptor gamma
FBXO40 F-box protein 40
FGF16 fibroblast growth factor 16
FGF18 fibroblast growth factor 18
FGL2 fibrinogen-like 2
FRMD4A FERM domain containing 4A
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAS7 growth arrest-specific 7
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GPATCH4 G patch domain containing 4
GRM7 glutamate receptor, metabotropic 7
GYG2 glycogenin 2
HPR haptoglobin-related protein
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL6 interleukin 6
INO80B INO80 complex subunit B
INSR insulin receptor
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MKRN3 makorin ring finger protein 3
MMP10 matrix metallopeptidase 10
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYH13 myosin, heavy chain 13, skeletal muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NEB nebulin
NEUROG2 neurogenin 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOVA2 neuro-oncological ventral antigen 2
NPC1 Niemann-Pick disease, type C1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPY2R neuropeptide Y receptor Y2
NTNG1 netrin G1
ONECUT2 one cut homeobox 2
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PHC3 polyhomeotic homolog 3 (Drosophila)
PLCH1 phospholipase C, eta 1
PLK4 polo-like kinase 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PPARD peroxisome proliferator-activated receptor delta
PRDM2 PR domain containing 2, with ZNF domain
PRSS8 protease, serine, 8
PTPRJ protein tyrosine phosphatase, receptor type, J
PVT1 Pvt1 oncogene (non-protein coding)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM26 RNA binding motif protein 26
RBMS2 RNA binding motif, single stranded interacting protein 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPB surfactant protein B
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC6A16 solute carrier family 6, member 16
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMAD5-AS1 SMAD5 antisense RNA 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPTBN1 spectrin, beta, non-erythrocytic 1
TGM4 transglutaminase 4
TIMELESS timeless circadian clock
TLX2 T-cell leukemia homeobox 2
TSC2 tuberous sclerosis 2
VAX2 ventral anterior homeobox 2
WDR55 WD repeat domain 55
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZC3H13 zinc finger CCCH-type containing 13
ZNF362 zinc finger protein 362
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM2 ADAM metallopeptidase domain 2
AKAP5 A kinase (PRKA) anchor protein 5
AMH anti-Mullerian hormone
ANKRD7 ankyrin repeat domain 7
ARHGAP24 Rho GTPase activating protein 24
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMCX4 armadillo repeat containing, X-linked 4
ARPIN actin-related protein 2/3 complex inhibitor
AURKC aurora kinase C
BEND5 BEN domain containing 5
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C3AR1 complement component 3a receptor 1
CAMKMT calmodulin-lysine N-methyltransferase
CCDC186 coiled-coil domain containing 186
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN2AIP CDKN2A interacting protein
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNN1 calponin 1, basic, smooth muscle
COG4 component of oligomeric golgi complex 4
CXORF21 chromosome X open reading frame 21
DMTN dematin actin binding protein
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP5 FK506 binding protein 5
GAN gigaxonin
GPR85 G protein-coupled receptor 85
GRM4 glutamate receptor, metabotropic 4
HIST1H3A histone cluster 1, H3a
HIST1H3C histone cluster 1, H3c
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL18R1 interleukin 18 receptor 1
IL36RN interleukin 36 receptor antagonist
IPO8 importin 8
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLF1 Kruppel-like factor 1 (erythroid)
KLF3 Kruppel-like factor 3 (basic)
KRT15 keratin 15, type I
LENEP lens epithelial protein
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LNPEP leucyl/cystinyl aminopeptidase
LOXL3 lysyl oxidase-like 3
LRP2 low density lipoprotein receptor-related protein 2
LRP4 low density lipoprotein receptor-related protein 4
LRRC2 leucine rich repeat containing 2
MANBA mannosidase, beta A, lysosomal
MMP2 matrix metallopeptidase 2
MRPL52 mitochondrial ribosomal protein L52
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
MYLIP myosin regulatory light chain interacting protein
NGF nerve growth factor (beta polypeptide)
NPPB natriuretic peptide B
NT5M 5',3'-nucleotidase, mitochondrial
OLFML3 olfactomedin-like 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLBD1 phospholipase B domain containing 1
PLD2 phospholipase D2
PRR4 proline rich 4 (lacrimal)
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRH protein tyrosine phosphatase, receptor type, H
RFPL1S RFPL1 antisense RNA 1
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S1PR1 sphingosine-1-phosphate receptor 1
SCGB2A1 secretoglobin, family 2A, member 1
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1A SET domain containing 1A
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SSTR4 somatostatin receptor 4
STEAP4 STEAP family member 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TENM4 teneurin transmembrane protein 4
TMEM115 transmembrane protein 115
TMEM53 transmembrane protein 53
TUBA3C tubulin, alpha 3c
WDR62 WD repeat domain 62
ZMAT4 zinc finger, matrin-type 4
ZNF222 zinc finger protein 222
ZNF254 zinc finger protein 254
ZNF549 zinc finger protein 549
ZSCAN2 zinc finger and SCAN domain containing 2
ZXDB zinc finger, X-linked, duplicated B