smoothened signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. (Gene Ontology, GO_0007224)
External Link http://amigo.geneontology.org/amigo/term/GO:0007224
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Genes

71 genes participating in the smoothened signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ARL13B ADP-ribosylation factor-like 13B
ARL3 ADP-ribosylation factor-like 3
B9D1 B9 protein domain 1
BBS7 Bardet-Biedl syndrome 7
BMP4 bone morphogenetic protein 4
BOC BOC cell adhesion associated, oncogene regulated
C21ORF2 chromosome 21 open reading frame 2
CC2D2A coiled-coil and C2 domain containing 2A
CDON cell adhesion associated, oncogene regulated
DISP1 dispatched homolog 1 (Drosophila)
DISP2 dispatched homolog 2 (Drosophila)
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EVC Ellis van Creveld protein
EVC2 Ellis van Creveld syndrome 2
FKBP8 FK506 binding protein 8, 38kDa
FOXF1 forkhead box F1
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPC2 glypican 2
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HHAT hedgehog acyltransferase
HHIP hedgehog interacting protein
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
HSPB11 heat shock protein family B (small), member 11
IFT122 intraflagellar transport 122
IFT172 intraflagellar transport 172
IFT20 intraflagellar transport 20
IFT27 intraflagellar transport 27
IFT46 intraflagellar transport 46
IFT52 intraflagellar transport 52
IFT57 intraflagellar transport 57
IFT80 intraflagellar transport 80
IFT88 intraflagellar transport 88
IHH indian hedgehog
IQUB IQ motif and ubiquitin domain containing
KIAA0586 KIAA0586
KIF27 kinesin family member 27
KIF7 kinesin family member 7
MAP3K10 mitogen-activated protein kinase kinase kinase 10
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NKX2-2 NK2 homeobox 2
NKX6-1 NK6 homeobox 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PAX6 paired box 6
PDX1 pancreatic and duodenal homeobox 1
PKD2L1 polycystic kidney disease 2-like 1
PTCH1 patched 1
PTCHD1 patched domain containing 1
PTCHD2 patched domain containing 2
SEPT2 septin 2
SHH sonic hedgehog
SMO smoothened, frizzled class receptor
STIL SCL/TAL1 interrupting locus
SUFU suppressor of fused homolog (Drosophila)
TBC1D32 TBC1 domain family, member 32
TCTN2 tectonic family member 2
TCTN3 tectonic family member 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM17 transmembrane protein 17
TMEM231 transmembrane protein 231
TROVE2 TROVE domain family, member 2
TTBK2 tau tubulin kinase 2
TTC21B tetratricopeptide repeat domain 21B
TTC26 tetratricopeptide repeat domain 26
TULP3 tubby like protein 3
WDPCP WD repeat containing planar cell polarity effector
WDR19 WD repeat domain 19
WNT10B wingless-type MMTV integration site family, member 10B