smooth muscle contraction Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. (Gene Ontology, GO_0006939)
External Link http://amigo.geneontology.org/amigo/term/GO:0006939
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Genes

46 genes participating in the smooth muscle contraction biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRA1A adrenoceptor alpha 1A
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BBS2 Bardet-Biedl syndrome 2
BDKRB2 bradykinin receptor B2
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CHRM3 cholinergic receptor, muscarinic 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
DLG1 discs, large homolog 1 (Drosophila)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
FKBP1B FK506 binding protein 1B, 12.6 kDa
GDNF glial cell derived neurotrophic factor
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KNG1 kininogen 1
MKKS McKusick-Kaufman syndrome
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NMUR1 neuromedin U receptor 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PDE4D phosphodiesterase 4D, cAMP-specific
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMTN smoothelin
SSTR2 somatostatin receptor 2
SULF1 sulfatase 1
SULF2 sulfatase 2
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TPCN2 two pore segment channel 2
TSHZ3 teashirt zinc finger homeobox 3