small spleen Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description decreased spleen size (Mammalian Phenotype Ontology, MP_0000692)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000692
Similar Terms
Downloads & Tools

Genes

202 gene mutations causing the small spleen phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR2B activin A receptor, type IIB
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
AKAP13 A kinase (PRKA) anchor protein 13
ALOX5 arachidonate 5-lipoxygenase
ALPL alkaline phosphatase, liver/bone/kidney
AMER1 APC membrane recruitment protein 1
ARHGAP1 Rho GTPase activating protein 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMC4 armadillo repeat containing 4
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASB1 ankyrin repeat and SOCS box containing 1
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BLNK B-cell linker
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA2 breast cancer 2, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF127 chromosome 1 open reading frame 127
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACYBP calcyclin binding protein
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CD2AP CD2-associated protein
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
CIDEB cell death-inducing DFFA-like effector b
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL10A1 collagen, type X, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
CORO1A coronin, actin binding protein, 1A
CSF1 colony stimulating factor 1 (macrophage)
CTC1 CTS telomere maintenance complex component 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYS1 cystin 1
DAW1 dynein assembly factor with WDR repeat domains 1
DCLRE1C DNA cross-link repair 1C
DEDD death effector domain containing
DNAH11 dynein, axonemal, heavy chain 11
DNAI1 dynein, axonemal, intermediate chain 1
DOCK2 dedicator of cytokinesis 2
DRD2 dopamine receptor D2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELAVL1 ELAV like RNA binding protein 1
ELMOD1 ELMO/CED-12 domain containing 1
EPOR erythropoietin receptor
ERCC1 excision repair cross-complementation group 1
ERCC5 excision repair cross-complementation group 5
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EWSR1 EWS RNA-binding protein 1
FGF10 fibroblast growth factor 10
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FIG4 FIG4 phosphoinositide 5-phosphatase
FLT3LG fms-related tyrosine kinase 3 ligand
FNIP1 folliculin interacting protein 1
FOXN1 forkhead box N1
FXR1 fragile X mental retardation, autosomal homolog 1
GHR growth hormone receptor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GLB1 galactosidase, beta 1
GLRA1 glycine receptor, alpha 1
GON4L gon-4-like (C. elegans)
GPC3 glypican 3
GRB14 growth factor receptor-bound protein 14
GSTK1 glutathione S-transferase kappa 1
GSTZ1 glutathione S-transferase zeta 1
HAX1 HCLS1 associated protein X-1
HELLS helicase, lymphoid-specific
HHIP hedgehog interacting protein
HOXA9 homeobox A9
HOXB4 homeobox B4
HTRA2 HtrA serine peptidase 2
ICOSLG inducible T-cell co-stimulator ligand
IFNGR1 interferon gamma receptor 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL7 interleukin 7
IL7R interleukin 7 receptor
INVS inversin
JAK3 Janus kinase 3
JARID2 jumonji, AT rich interactive domain 2
KAT6A K(lysine) acetyltransferase 6A
KDM8 lysine (K)-specific demethylase 8
KIAA0101 KIAA0101
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLHL6 kelch-like family member 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2E lysine (K)-specific methyltransferase 2E
LBR lamin B receptor
LIG4 ligase IV, DNA, ATP-dependent
LMNA lamin A/C
LRFN2 leucine rich repeat and fibronectin type III domain containing 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSI2 musashi RNA-binding protein 2
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MXRA7 matrix-remodelling associated 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NHEJ1 nonhomologous end-joining factor 1
NKX2-3 NK2 homeobox 3
NKX2-5 NK2 homeobox 5
NLK nemo-like kinase
NODAL nodal growth differentiation factor
NPR2 natriuretic peptide receptor 2
NPY1R neuropeptide Y receptor Y1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PARL presenilin associated, rhomboid-like
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDPK1 3-phosphoinositide dependent protein kinase 1
PFDN1 prefoldin subunit 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITX2 paired-like homeodomain 2
POU2AF1 POU class 2 associating factor 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSAP prosaposin
PSIP1 PC4 and SFRS1 interacting protein 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTTG1 pituitary tumor-transforming 1
PURA purine-rich element binding protein A
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOH ras homolog family member H
RORA RAR-related orphan receptor A
RPL27A ribosomal protein L27a
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX1 runt-related transcription factor 1
SATB1 SATB homeobox 1
SCG5 secretogranin V
SELENBP1 selenium binding protein 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGPL1 sphingosine-1-phosphate lyase 1
SIAE sialic acid acetylesterase
SIRT6 sirtuin 6
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SMAD3 SMAD family member 3
SNX27 sorting nexin family member 27
SP4 Sp4 transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
SPPL2A signal peptide peptidase like 2A
STK36 serine/threonine kinase 36
TBC1D32 TBC1 domain family, member 32
TBC1D4 TBC1 domain family, member 4
TCF3 transcription factor 3
TDP2 tyrosyl-DNA phosphodiesterase 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TK1 thymidine kinase 1, soluble
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNS3 tensin 3
TP53 tumor protein p53
TPO thyroid peroxidase
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAT1 T cell receptor associated transmembrane adaptor 1
WWOX WW domain containing oxidoreductase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZEB1 zinc finger E-box binding homeobox 1
ZFPM1 zinc finger protein, FOG family member 1
ZIC3 Zic family member 3