small liver Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description reduced size of the liver (Mammalian Phenotype Ontology, MP_0000601)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000601
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Genes

158 gene mutations causing the small liver phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADA adenosine deaminase
ADAR adenosine deaminase, RNA-specific
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AIP aryl hydrocarbon receptor interacting protein
ARF6 ADP-ribosylation factor 6
ARHGAP1 Rho GTPase activating protein 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATR ATR serine/threonine kinase
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BCAR1 breast cancer anti-estrogen resistance 1
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BMP5 bone morphogenetic protein 5
BRD1 bromodomain containing 1
BSG basigin (Ok blood group)
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CCBE1 collagen and calcium binding EGF domains 1
CCNG1 cyclin G1
CES1 carboxylesterase 1
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CIAPIN1 cytokine induced apoptosis inhibitor 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CRBN cereblon
CSHL1 chorionic somatomammotropin hormone-like 1
CTHRC1 collagen triple helix repeat containing 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR2 chemokine (C-X-C motif) receptor 2
DEDD death effector domain containing
DICER1 dicer 1, ribonuclease type III
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF6 eukaryotic translation initiation factor 6
EPO erythropoietin
EPOR erythropoietin receptor
ERCC5 excision repair cross-complementation group 5
ERN1 endoplasmic reticulum to nucleus signaling 1
FABP2 fatty acid binding protein 2, intestinal
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP6 fatty acid binding protein 6, ileal
FLI1 Fli-1 proto-oncogene, ETS transcription factor
G0S2 G0/G1 switch 2
GAB1 GRB2-associated binding protein 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GHR growth hormone receptor
GLB1 galactosidase, beta 1
GNMT glycine N-methyltransferase
GPER1 G protein-coupled estrogen receptor 1
GRB14 growth factor receptor-bound protein 14
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLX H2.0-like homeobox
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JAK2 Janus kinase 2
JARID2 jumonji, AT rich interactive domain 2
JMJD6 jumonji domain containing 6
JUND jun D proto-oncogene
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KITLG KIT ligand
KL klotho
KLF1 Kruppel-like factor 1 (erythroid)
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX2 LIM homeobox 2
LIG1 ligase I, DNA, ATP-dependent
LSR lipolysis stimulated lipoprotein receptor
MAPK14 mitogen-activated protein kinase 14
MAPK6 mitogen-activated protein kinase 6
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBD5 methyl-CpG binding domain protein 5
MBTD1 mbt domain containing 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEIS1 Meis homeobox 1
MET MET proto-oncogene, receptor tyrosine kinase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MSTN myostatin
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA3 nuclear receptor coactivator 3
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NEGR1 neuronal growth regulator 1
NF1 neurofibromin 1
NFE2L1 nuclear factor, erythroid 2-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NODAL nodal growth differentiation factor
PBRM1 polybromo 1
PBX1 pre-B-cell leukemia homeobox 1
PDGFB platelet-derived growth factor beta polypeptide
PLA2G1B phospholipase A2, group IB (pancreas)
PNLIP pancreatic lipase
POU2F1 POU class 2 homeobox 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRL prolactin
PROX1 prospero homeobox 1
PSAP prosaposin
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RCAN2 regulator of calcineurin 2
RDH10 retinol dehydrogenase 10 (all-trans)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
SELENBP1 selenium binding protein 1
SENP1 SUMO1/sentrin specific peptidase 1
SERTAD2 SERTA domain containing 2
SIAH1 siah E3 ubiquitin protein ligase 1
SIK3 SIK family kinase 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNX27 sorting nexin family member 27
SOCS3 suppressor of cytokine signaling 3
SOX17 SRY (sex determining region Y)-box 17
SP3 Sp3 transcription factor
SPEN spen family transcriptional repressor
SPTBN1 spectrin, beta, non-erythrocytic 1
SRA1 steroid receptor RNA activator 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STARD4 StAR-related lipid transfer (START) domain containing 4
TACC3 transforming, acidic coiled-coil containing protein 3
TBX3 T-box 3
TCEA1 transcription elongation factor A (SII), 1
THRA thyroid hormone receptor, alpha
TKT transketolase
TMOD3 tropomodulin 3 (ubiquitous)
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTC7A tetratricopeptide repeat domain 7A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
XIRP2 xin actin binding repeat containing 2
XPA xeroderma pigmentosum, complementation group A
YBX1 Y box binding protein 1
ZFPM1 zinc finger protein, FOG family member 1
ZFPM2 zinc finger protein, FOG family member 2