small gtpase mediated signal transduction Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. (Gene Ontology, GO_0007264)
External Link http://amigo.geneontology.org/amigo/term/GO:0007264
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Genes

425 genes participating in the small gtpase mediated signal transduction biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
AATK apoptosis-associated tyrosine kinase
ABI2 abl-interactor 2
ABR active BCR-related
ADGRG1 adhesion G protein-coupled receptor G1
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGTR1 angiotensin II receptor, type 1
AIF1 allograft inflammatory factor 1
AKAP13 A kinase (PRKA) anchor protein 13
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF1 ADP-ribosylation factor 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARF6 ADP-ribosylation factor 6
ARFIP2 ADP-ribosylation factor interacting protein 2
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP32 Rho GTPase activating protein 32
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARHGAP36 Rho GTPase activating protein 36
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP44 Rho GTPase activating protein 44
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL1 ADP-ribosylation factor-like 1
ARL10 ADP-ribosylation factor-like 10
ARL11 ADP-ribosylation factor-like 11
ARL13A ADP-ribosylation factor-like 13A
ARL13B ADP-ribosylation factor-like 13B
ARL14 ADP-ribosylation factor-like 14
ARL15 ADP-ribosylation factor-like 15
ARL16 ADP-ribosylation factor-like 16
ARL2 ADP-ribosylation factor-like 2
ARL3 ADP-ribosylation factor-like 3
ARL4A ADP-ribosylation factor-like 4A
ARL4C ADP-ribosylation factor-like 4C
ARL4D ADP-ribosylation factor-like 4D
ARL5A ADP-ribosylation factor-like 5A
ARL5B ADP-ribosylation factor-like 5B
ARL5C ADP-ribosylation factor-like 5C
ARL6 ADP-ribosylation factor-like 6
ARL8A ADP-ribosylation factor-like 8A
ARL8B ADP-ribosylation factor-like 8B
ARL9 ADP-ribosylation factor-like 9
BCAR3 breast cancer anti-estrogen resistance 3
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
C15ORF62 chromosome 15 open reading frame 62
CCNA2 cyclin A2
CDC42 cell division cycle 42
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5
CDH13 cadherin 13
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CFL1 cofilin 1 (non-muscle)
CHN1 chimerin 1
CHN2 chimerin 2
CHP1 calcineurin-like EF-hand protein 1
CHUK conserved helix-loop-helix ubiquitous kinase
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL1A2 collagen, type I, alpha 2
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CYFIP1 cytoplasmic FMR1 interacting protein 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBNL drebrin-like
DEPDC1B DEP domain containing 1B
DEPDC7 DEP domain containing 7
DHCR24 24-dehydrocholesterol reductase
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DLC1 DLC1 Rho GTPase activating protein
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27
DOCK1 dedicator of cytokinesis 1
DOCK10 dedicator of cytokinesis 10
DOCK11 dedicator of cytokinesis 11
DOCK2 dedicator of cytokinesis 2
DOCK3 dedicator of cytokinesis 3
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DOCK6 dedicator of cytokinesis 6
DOCK7 dedicator of cytokinesis 7
DOCK8 dedicator of cytokinesis 8
DOCK9 dedicator of cytokinesis 9
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
ECT2 epithelial cell transforming 2
EDNRA endothelin receptor type A
ELMO1 engulfment and cell motility 1
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
ERAS ES cell expressed Ras
FAM13A family with sequence similarity 13, member A
FAM13B family with sequence similarity 13, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGF2 fibroblast growth factor 2 (basic)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GDI1 GDP dissociation inhibitor 1
GDI2 GDP dissociation inhibitor 2
GEM GTP binding protein overexpressed in skeletal muscle
GMIP GEM interacting protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HMHA1 histocompatibility (minor) HA-1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
IFT22 intraflagellar transport 22
IFT27 intraflagellar transport 27
IGF1 insulin-like growth factor 1 (somatomedin C)
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
KSR1 kinase suppressor of ras 1
LAT linker for activation of T cells
LIMK1 LIM domain kinase 1
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MRAS muscle RAS oncogene homolog
MYO9A myosin IXA
MYO9B myosin IXB
NCKAP1 NCK-associated protein 1
NET1 neuroepithelial cell transforming 1
NF1 neurofibromin 1
NGEF neuronal guanine nucleotide exchange factor
NGF nerve growth factor (beta polypeptide)
NISCH nischarin
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL oculocerebrorenal syndrome of Lowe
OPHN1 oligophrenin 1
PARK7 parkinson protein 7
PHACTR4 phosphatase and actin regulator 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCE1 phospholipase C, epsilon 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLK2 polo-like kinase 2
PTH parathyroid hormone
RAB10 RAB10, member RAS oncogene family
RAB11A RAB11A, member RAS oncogene family
RAB11B RAB11B, member RAS oncogene family
RAB12 RAB12, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RAB15 RAB15, member RAS oncogene family
RAB17 RAB17, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB19 RAB19, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB1B RAB1B, member RAS oncogene family
RAB20 RAB20, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB22A RAB22A, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB24 RAB24, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RAB26 RAB26, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB2B RAB2B, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB32 RAB32, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RAB37 RAB37, member RAS oncogene family
RAB38 RAB38, member RAS oncogene family
RAB39A RAB39A, member RAS oncogene family
RAB39B RAB39B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RAB40B RAB40B, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAB41 RAB41, member RAS oncogene family
RAB42 RAB42, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAB6C RAB6C, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAB9B RAB9B, member RAS oncogene family
RABIF RAB interacting factor
RABL2A RAB, member of RAS oncogene family-like 2A
RABL2B RAB, member of RAS oncogene family-like 2B
RABL3 RAB, member of RAS oncogene family-like 3
RABL6 RAB, member RAS oncogene family-like 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RACGAP1 Rac GTPase activating protein 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALBP1 ralA binding protein 1
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAN RAN, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RAP2C RAP2C, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASD1 RAS, dexamethasone-induced 1
RASD2 RASD family, member 2
RASEF RAS and EF-hand domain containing
RASGEF1A RasGEF domain family, member 1A
RASGEF1B RasGEF domain family, member 1B
RASGEF1C RasGEF domain family, member 1C
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RASGRP4 RAS guanyl releasing protein 4
RASL10A RAS-like, family 10, member A
RASL10B RAS-like, family 10, member B
RASL11A RAS-like, family 11, member A
RASL11B RAS-like, family 11, member B
RASL12 RAS-like, family 12
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
REM2 RAS (RAD and GEM)-like GTP binding 2
RERG RAS-like, estrogen-regulated, growth inhibitor
RERGL RERG/RAS-like
RFXANK regulatory factor X-associated ankyrin-containing protein
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RGL3 ral guanine nucleotide dissociation stimulator-like 3
RGL4 ral guanine nucleotide dissociation stimulator-like 4
RGS19 regulator of G-protein signaling 19
RHEB Ras homolog enriched in brain
RHEBL1 Ras homolog enriched in brain like 1
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOBTB1 Rho-related BTB domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RHOBTB3 Rho-related BTB domain containing 3
RHOC ras homolog family member C
RHOD ras homolog family member D
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOH ras homolog family member H
RHOJ ras homolog family member J
RHOQ ras homolog family member Q
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RHOU ras homolog family member U
RHOV ras homolog family member V
RIN2 Ras and Rab interactor 2
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
RND1 Rho family GTPase 1
RND2 Rho family GTPase 2
RND3 Rho family GTPase 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROPN1B rhophilin associated tail protein 1B
RRAD Ras-related associated with diabetes
RRAGC Ras-related GTP binding C
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RREB1 ras responsive element binding protein 1
RSG1 REM2 and RAB-like small GTPase 1
RSU1 Ras suppressor protein 1
RTKN rhotekin
RUNDC3A RUN domain containing 3A
SDCBP syndecan binding protein (syntenin)
SGSM3 small G protein signaling modulator 3
SH2D3A SH2 domain containing 3A
SH2D3C SH2 domain containing 3C
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIAH2 siah E3 ubiquitin protein ligase 2
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRPRB signal recognition particle receptor, B subunit
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
SYNGAP1 synaptic Ras GTPase activating protein 1
TAGAP T-cell activation RhoGTPase activating protein
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TRIM23 tripartite motif containing 23
TRIO trio Rho guanine nucleotide exchange factor
TRIP10 thyroid hormone receptor interactor 10
ULK1 unc-51 like autophagy activating kinase 1
USP8 ubiquitin specific peptidase 8
VANGL2 VANGL planar cell polarity protein 2
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta