small cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A carcinoma that is an undifferentiated neoplasm composed of primitive-appearing cells. (Human Disease Ontology, DOID_0050685)
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Genes

154 genes co-occuring with the disease small cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ENO2 enolase 2 (gamma, neuronal) 2.44394
CNN1 calponin 1, basic, smooth muscle 2.37576
SYP synaptophysin 2.19403
TAGLN transgelin 2.09242
CHGA chromogranin A 1.98668
GRP gastrin-releasing peptide 1.75142
NCAM1 neural cell adhesion molecule 1 1.70861
NKX2-1 NK2 homeobox 1 1.65115
KRT20 keratin 20, type I 1.56667
POMC proopiomelanocortin 1.40789
KLK7 kallikrein-related peptidase 7 1.36509
B3GAT1 beta-1,3-glucuronyltransferase 1 1.3337
CALCA calcitonin-related polypeptide alpha 1.29483
AVP arginine vasopressin 1.25254
KRT7 keratin 7, type II 1.23256
TP53 tumor protein p53 1.20829
KLK3 kallikrein-related peptidase 3 1.08244
KRT5 keratin 5, type II 1.05009
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.02102
PTPRC protein tyrosine phosphatase, receptor type, C 0.951604
ASCL1 achaete-scute family bHLH transcription factor 1 0.917611
KRT19 keratin 19, type I 0.898282
KLK8 kallikrein-related peptidase 8 0.889668
DPYSL5 dihydropyrimidinase-like 5 0.8741
AVPR1A arginine vasopressin receptor 1A 0.872872
KRT8 keratin 8, type II 0.862228
GLE1 GLE1 RNA export mediator 0.856087
CD99 CD99 molecule 0.807308
SST somatostatin 0.781479
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.762678
TMPRSS2 transmembrane protease, serine 2 0.753713
GSTM1 glutathione S-transferase mu 1 0.743547
RCVRN recoverin 0.730166
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.714005
GAST gastrin 0.697911
EWSR1 EWS RNA-binding protein 1 0.682294
ACPP acid phosphatase, prostate 0.665563
PTHLH parathyroid hormone-like hormone 0.657234
IGSF3 immunoglobulin superfamily, member 3 0.656046
CDKN2A cyclin-dependent kinase inhibitor 2A 0.644586
NAPSA napsin A aspartic peptidase 0.635135
TTF1 transcription termination factor, RNA polymerase I 0.634742
HYAL3 hyaluronoglucosaminidase 3 0.631598
CDR2L cerebellar degeneration-related protein 2-like 0.620226
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.611229
KRT14 keratin 14, type I 0.588222
AFP alpha-fetoprotein 0.529222
KLK15 kallikrein-related peptidase 15 0.519961
NPS neuropeptide S 0.517265
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.515725
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.514956
CDX2 caudal type homeobox 2 0.489691
PTH parathyroid hormone 0.483604
LEMD1 LEM domain containing 1 0.47753
CRH corticotropin releasing hormone 0.475255
CCNB3 cyclin B3 0.466172
PRKCDBP protein kinase C, delta binding protein 0.458996
AR androgen receptor 0.458241
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.43941
SV2B synaptic vesicle glycoprotein 2B 0.436026
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.430393
HRAS Harvey rat sarcoma viral oncogene homolog 0.415398
GATA3 GATA binding protein 3 0.415024
ENO1 enolase 1, (alpha) 0.407545
ERBB2 erb-b2 receptor tyrosine kinase 2 0.402692
GSTA3 glutathione S-transferase alpha 3 0.399707
GSTA2 glutathione S-transferase alpha 2 0.398216
GSTA4 glutathione S-transferase alpha 4 0.397098
SCG5 secretogranin V 0.394491
GSTA1 glutathione S-transferase alpha 1 0.391513
CSH2 chorionic somatomammotropin hormone 2 0.385565
UPK3A uroplakin 3A 0.382223
ZNF135 zinc finger protein 135 0.377031
PCSK9 proprotein convertase subtilisin/kexin type 9 0.371847
MUC1 mucin 1, cell surface associated 0.369258
PCNA proliferating cell nuclear antigen 0.357077
UBE2T ubiquitin-conjugating enzyme E2T 0.35082
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.348246
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.341272
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.333218
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.331025
WT1 Wilms tumor 1 0.32009
STC1 stanniocalcin 1 0.315003
KRAS Kirsten rat sarcoma viral oncogene homolog 0.313915
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.312827
PGR progesterone receptor 0.312464
BIRC7 baculoviral IAP repeat containing 7 0.312464
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.311739
DES desmin 0.311739
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.308842
AVPR1B arginine vasopressin receptor 1B 0.308118
BEST3 bestrophin 3 0.307033
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.294053
DUS2 dihydrouridine synthase 2 0.286877
NKX3-1 NK3 homeobox 1 0.284728
AKR1C3 aldo-keto reductase family 1, member C3 0.284371
AMACR alpha-methylacyl-CoA racemase 0.283655
PAX2 paired box 2 0.281153
MUC6 mucin 6, oligomeric mucus/gel-forming 0.280439
ALPPL2 alkaline phosphatase, placental-like 2 0.277584
CUL5 cullin 5 0.277227
ALPP alkaline phosphatase, placental 0.277227
ALPL alkaline phosphatase, liver/bone/kidney 0.27687
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.274376
CCND1 cyclin D1 0.273308
RIPK3 receptor-interacting serine-threonine kinase 3 0.269753
CD8B CD8b molecule 0.269398
GCAT glycine C-acetyltransferase 0.266203
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.263368
PXDN peroxidasin 0.259124
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.25877
AMPH amphiphysin 0.25877
MKI67 marker of proliferation Ki-67 0.258064
GSTP1 glutathione S-transferase pi 1 0.250311
PAX5 paired box 5 0.248554
HIST1H1B histone cluster 1, H1b 0.245747
NTS neurotensin 0.245396
CD109 CD109 molecule 0.241895
B2M beta-2-microglobulin 0.230755
LDHC lactate dehydrogenase C 0.230063
KRT18 keratin 18, type I 0.229716
EGFR epidermal growth factor receptor 0.221108
OAT ornithine aminotransferase 0.220766
ESR1 estrogen receptor 1 0.214636
VIL1 villin 1 0.212271
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.209918
S100P S100 calcium binding protein P 0.209248
XAGE1E X antigen family, member 1E 0.20229
FBXO42 F-box protein 42 0.200331
MYOG myogenin (myogenic factor 4) 0.199033
LCN1 lipocalin 1 0.198064
RAB25 RAB25, member RAS oncogene family 0.197742
HDC histidine decarboxylase 0.197099
MALL mal, T-cell differentiation protein-like 0.194548
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.193285
XAGE1B X antigen family, member 1B 0.192344
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.191097
BPIFA1 BPI fold containing family A, member 1 0.190476
FXR1 fragile X mental retardation, autosomal homolog 1 0.189859
CST7 cystatin F (leukocystatin) 0.18621
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.185612
TCEA1 transcription elongation factor A (SII), 1 0.182086
CD6 CD6 molecule 0.18151
PCSK2 proprotein convertase subtilisin/kexin type 2 0.178682
PIDD1 p53-induced death domain protein 1 0.177851
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.175411
AURKA aurora kinase A 0.171535
GCG glucagon 0.171535
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.168381
CD86 CD86 molecule 0.168148
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.167452
MYOD1 myogenic differentiation 1 0.162505
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.161912
F3 coagulation factor III (thromboplastin, tissue factor) 0.158778