smad protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that consists of SMAD proteins; may be homomeric or heteromeric. (Gene Ontology, GO_0071141)
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172 proteins co-occuring with the smad protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SMAD4 SMAD family member 4 3.07973
SMAD2 SMAD family member 2 2.91992
SMAD3 SMAD family member 3 2.90383
TGFB1 transforming growth factor, beta 1 2.87547
SMAD7 SMAD family member 7 2.49858
SMAD5 SMAD family member 5 2.05612
SMAD6 SMAD family member 6 1.84566
SMAD9 SMAD family member 9 1.60651
TGFBR1 transforming growth factor, beta receptor 1 1.5943
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.51581
SKI SKI proto-oncogene 1.3412
BMP2 bone morphogenetic protein 2 1.33576
FOXH1 forkhead box H1 1.31843
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.27133
ACVR1B activin A receptor, type IB 1.26392
BMP4 bone morphogenetic protein 4 1.20601
ZFYVE9 zinc finger, FYVE domain containing 9 1.1046
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.06397
ACVR2A activin A receptor, type IIA 1.06094
BMPR1A bone morphogenetic protein receptor, type IA 0.989759
ACVR1C activin A receptor, type IC 0.975166
SKOR2 SKI family transcriptional corepressor 2 0.90739
BMP7 bone morphogenetic protein 7 0.891631
SAMD3 sterile alpha motif domain containing 3 0.869966
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.857095
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.844237
NOG noggin 0.830466
TIAF1 TGFB1-induced anti-apoptotic factor 1 0.811193
FSHB follicle stimulating hormone, beta polypeptide 0.807524
ZEB2 zinc finger E-box binding homeobox 2 0.784614
CTGF connective tissue growth factor 0.734217
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.682027
ACVR1 activin A receptor, type I 0.681155
KLF14 Kruppel-like factor 14 0.64958
FST follistatin 0.637578
JUN jun proto-oncogene 0.634586
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.622229
ALK anaplastic lymphoma receptor tyrosine kinase 0.605706
E2F4 E2F transcription factor 4, p107/p130-binding 0.590553
EID2 EP300 interacting inhibitor of differentiation 2 0.583012
HOXC8 homeobox C8 0.570913
LGALS4 lectin, galactoside-binding, soluble, 4 0.57008
MAPK14 mitogen-activated protein kinase 14 0.565508
TGFB2 transforming growth factor, beta 2 0.549773
JUNB jun B proto-oncogene 0.545648
SMAD1 SMAD family member 1 0.543176
RUNX2 runt-related transcription factor 2 0.540294
SAMD1 sterile alpha motif domain containing 1 0.536183
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.53413
CHRD chordin 0.519389
FOXE3 forkhead box E3 0.518165
SPTSSB serine palmitoyltransferase, small subunit B 0.5149
GTPBP2 GTP binding protein 2 0.511233
CREBBP CREB binding protein 0.508383
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.504724
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 0.504318
TDP2 tyrosyl-DNA phosphodiesterase 2 0.491752
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.484079
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.483676
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.481661
COL1A2 collagen, type I, alpha 2 0.466799
BMP6 bone morphogenetic protein 6 0.454816
OVOL1 ovo-like zinc finger 1 0.454816
MSTN myostatin 0.41612
BAMBI BMP and activin membrane-bound inhibitor 0.414555
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.403637
AMHR2 anti-Mullerian hormone receptor, type II 0.397811
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.394323
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.380429
SP1 Sp1 transcription factor 0.380045
GADD45B growth arrest and DNA-damage-inducible, beta 0.376202
SKOR1 SKI family transcriptional corepressor 1 0.365095
MARK3 MAP/microtubule affinity-regulating kinase 3 0.364331
OLIG1 oligodendrocyte transcription factor 1 0.361277
MAPK11 mitogen-activated protein kinase 11 0.357847
ENG endoglin 0.353282
JUND jun D proto-oncogene 0.34645
ZEB1 zinc finger E-box binding homeobox 1 0.343042
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.340395
PARK2 parkin RBR E3 ubiquitin protein ligase 0.336241
FN1 fibronectin 1 0.333979
BMP3 bone morphogenetic protein 3 0.333602
MARK2 MAP/microtubule affinity-regulating kinase 2 0.332848
RNF111 ring finger protein 111 0.332848
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.332472
MIR21 microRNA 21 0.329837
SNW1 SNW domain containing 1 0.327581
FOXL1 forkhead box L1 0.320077
GDF2 growth differentiation factor 2 0.311851
MTMR4 myotubularin related protein 4 0.310358
TFE3 transcription factor binding to IGHM enhancer 3 0.308494
ECSIT ECSIT signalling integrator 0.305515
BMP10 bone morphogenetic protein 10 0.294748
MT3 metallothionein 3 0.291787
LEMD3 LEM domain containing 3 0.28846
RYK receptor-like tyrosine kinase 0.286983
DLX4 distal-less homeobox 4 0.281085
ACVRL1 activin A receptor type II-like 1 0.278877
CYR61 cysteine-rich, angiogenic inducer, 61 0.277038
NKX2-5 NK2 homeobox 5 0.276671
SNIP1 Smad nuclear interacting protein 1 0.276304
RBPMS RNA binding protein with multiple splicing 0.273734
TOB2 transducer of ERBB2, 2 0.264215
GDF6 growth differentiation factor 6 0.262025
MXD1 MAX dimerization protein 1 0.26166
AMH anti-Mullerian hormone 0.26166
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.260202
ERF Ets2 repressor factor 0.258016
LOXL4 lysyl oxidase-like 4 0.256925
PMEPA1 prostate transmembrane protein, androgen induced 1 0.249302
TRIM33 tripartite motif containing 33 0.248578
ZFYVE16 zinc finger, FYVE domain containing 16 0.246046
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.245685
IGSF1 immunoglobulin superfamily, member 1 0.242797
PIAS4 protein inhibitor of activated STAT, 4 0.241716
ZBTB17 zinc finger and BTB domain containing 17 0.240636
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.240636
GDF10 growth differentiation factor 10 0.237401
HFE2 hemochromatosis type 2 (juvenile) 0.237401
BGLAP bone gamma-carboxyglutamate (gla) protein 0.236683
FOS FBJ murine osteosarcoma viral oncogene homolog 0.233817
DROSHA drosha, ribonuclease type III 0.233817
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.232744
HOXA11 homeobox A11 0.229888
SKIL SKI-like proto-oncogene 0.228819
FOXL2 forkhead box L2 0.225976
GATA2 GATA binding protein 2 0.224204
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.220321
TFR2 transferrin receptor 2 0.21681
ADGRG2 adhesion G protein-coupled receptor G2 0.213669
CNN3 calponin 3, acidic 0.210549
MMP10 matrix metallopeptidase 10 0.208481
HAMP hepcidin antimicrobial peptide 0.207794
LPAR4 lysophosphatidic acid receptor 4 0.207108
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.206423
ZMIZ1 zinc finger, MIZ-type containing 1 0.206082
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.199993
ITGB8 integrin, beta 8 0.198325
ITGB6 integrin, beta 6 0.198325
ACVR2B activin A receptor, type IIB 0.19601
RNF6 ring finger protein (C3H2C3 type) 6 0.195025
PLG plasminogen 0.194698
RGMA repulsive guidance molecule family member a 0.189539
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.188274
CREB1 cAMP responsive element binding protein 1 0.188274
FOXE1 forkhead box E1 0.178011
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.177154
IPO7 importin 7 0.176024
KLK7 kallikrein-related peptidase 7 0.172468
RPL26L1 ribosomal protein L26-like 1 0.171937
MAP2K6 mitogen-activated protein kinase kinase 6 0.171673
TLE4 transducin-like enhancer of split 4 0.16233
PTHLH parathyroid hormone-like hormone 0.162117
OTX1 orthodenticle homeobox 1 0.161693
FOXF1 forkhead box F1 0.160863
ALPPL2 alkaline phosphatase, placental-like 2 0.160658
EMX2 empty spiracles homeobox 2 0.160658
ALPL alkaline phosphatase, liver/bone/kidney 0.160254
ALPP alkaline phosphatase, placental 0.160053
HOXA13 homeobox A13 0.158315
TOB1 transducer of ERBB2, 1 0.157397
LPAR1 lysophosphatidic acid receptor 1 0.156863
MYOG myogenin (myogenic factor 4) 0.156513
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.14041
MMP12 matrix metallopeptidase 12 0.137394
KDR kinase insert domain receptor 0.132949
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.132315
MMP3 matrix metallopeptidase 3 0.129464
NKX2-1 NK2 homeobox 1 0.128458
TIMP1 TIMP metallopeptidase inhibitor 1 0.125819
APOC3 apolipoprotein C-III 0.125238
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.12075