sleep disorder Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A disease of mental health that involves disruption of sleep patterns. (Human Disease Ontology, DOID_535)
Similar Terms
Downloads & Tools

Genes

137 genes co-occuring with the disease sleep disorder in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HCRT hypocretin (orexin) neuropeptide precursor 3.43111
HCRTR1 hypocretin (orexin) receptor 1 1.7957
IGLON5 IgLON family member 5 1.72867
PER2 period circadian clock 2 1.59385
FXYD1 FXYD domain containing ion transport regulator 1 1.54628
NPS neuropeptide S 1.41665
TRIB2 tribbles pseudokinase 2 1.33632
HCRTR2 hypocretin (orexin) receptor 2 1.25254
CHKB choline kinase beta 1.20093
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.14051
CLOCK clock circadian regulator 1.13628
NCKAP5 NCK-associated protein 5 1.03535
HLA-C major histocompatibility complex, class I, C 1.02861
PAIP2 poly(A) binding protein interacting protein 2 0.992752
FAM3D family with sequence similarity 3, member D 0.988535
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.951187
ATP13A4 ATPase type 13A4 0.947435
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.920911
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.895
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.846259
GPR50 G protein-coupled receptor 50 0.831099
TIMELESS timeless circadian clock 0.814693
DYNLT3 dynein, light chain, Tctex-type 3 0.804846
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.792131
ATXN3 ataxin 3 0.789672
CDH9 cadherin 9, type 2 (T1-cadherin) 0.76431
PER3 period circadian clock 3 0.762271
RBM4 RNA binding motif protein 4 0.758601
IGSF6 immunoglobulin superfamily, member 6 0.752898
HRH3 histamine receptor H3 0.742735
BTBD9 BTB (POZ) domain containing 9 0.737865
CSNK1D casein kinase 1, delta 0.735027
FRRS1L ferric-chelate reductase 1-like 0.735027
OXR1 oxidation resistance 1 0.702732
LEP leptin 0.680697
PRSS30P protease, serine, 30, pseudogene 0.667152
TSEN54 TSEN54 tRNA splicing endonuclease subunit 0.66596
NPPB natriuretic peptide B 0.66596
ELP4 elongator acetyltransferase complex subunit 4 0.637102
OPRD1 opioid receptor, delta 1 0.635135
DIAPH3 diaphanous-related formin 3 0.626103
CSN1S1 casein alpha s1 0.614747
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.612011
KLK15 kallikrein-related peptidase 15 0.582773
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.578106
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.547807
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.547807
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.541992
IK IK cytokine, down-regulator of HLA II 0.526518
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.522659
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.518805
NPPA natriuretic peptide A 0.511112
GHRL ghrelin/obestatin prepropeptide 0.497703
ART1 ADP-ribosyltransferase 1 0.490454
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.476014
NOTO notochord homeobox 0.458619
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.457864
NPAS2 neuronal PAS domain protein 2 0.445805
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.442042
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.43753
IREB2 iron-responsive element binding protein 2 0.428516
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.411657
DAOA D-amino acid oxidase activator 0.410161
TRIB3 tribbles pseudokinase 3 0.406051
TPH2 tryptophan hydroxylase 2 0.395608
PCP2 Purkinje cell protein 2 0.392257
AURKAIP1 aurora kinase A interacting protein 1 0.390769
CGA glycoprotein hormones, alpha polypeptide 0.385936
UBE3A ubiquitin protein ligase E3A 0.382594
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.376661
SPRED1 sprouty-related, EVH1 domain containing 1 0.372958
ARID1B AT rich interactive domain 1B (SWI1-like) 0.362978
LSR lipolysis stimulated lipoprotein receptor 0.358551
SMTNL1 smoothelin-like 1 0.356341
BTG2 BTG family, member 2 0.351923
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.348981
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.348614
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.347144
CRY2 cryptochrome circadian clock 2 0.344941
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.337242
CRAT carnitine O-acetyltransferase 0.336876
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.333218
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.331391
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.321545
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.313915
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.309204
PROKR2 prokineticin receptor 2 0.302337
CRY1 cryptochrome circadian clock 1 0.290462
ACSL1 acyl-CoA synthetase long-chain family member 1 0.270819
OPRK1 opioid receptor, kappa 1 0.267622
CTSH cathepsin H 0.265849
NRCAM neuronal cell adhesion molecule 0.264431
PTK7 protein tyrosine kinase 7 (inactive) 0.261245
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.257005
TRH thyrotropin-releasing hormone 0.252422
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.243645
SRPX2 sushi-repeat containing protein, X-linked 2 0.242945
POMC proopiomelanocortin 0.238403
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.236312
FTH1 ferritin, heavy polypeptide 1 0.232489
FTL ferritin, light polypeptide 0.232489
CNTNAP2 contactin associated protein-like 2 0.230755
DYNLT1 dynein, light chain, Tctex-type 1 0.218374
PROK2 prokineticin 2 0.210589
KRT16 keratin 16, type I 0.201635
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.200006
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.190476
NCR3 natural cytotoxicity triggering receptor 3 0.175679
CHRM3 cholinergic receptor, muscarinic 3 0.173832
CRH corticotropin releasing hormone 0.173057
TNF tumor necrosis factor 0.162306
MEIS1 Meis homeobox 1 0.159302
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.158434
RHCE Rh blood group, CcEe antigens 0.142565
CORT cortistatin 0.141934
TPH1 tryptophan hydroxylase 1 0.14102
RHD Rh blood group, D antigen 0.140948
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.140232
LCK LCK proto-oncogene, Src family tyrosine kinase 0.137459
COMT catechol-O-methyltransferase 0.133659
CPB1 carboxypeptidase B1 (tissue) 0.132648
CHKA choline kinase alpha 0.131995
CCNA2 cyclin A2 0.131541
EP300 E1A binding protein p300 0.131397
TACR1 tachykinin receptor 1 0.12905
MAOA monoamine oxidase A 0.126194
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.119861
NOS2 nitric oxide synthase 2, inducible 0.117771
FGFR3 fibroblast growth factor receptor 3 0.116974
S100B S100 calcium binding protein B 0.116493
MECP2 methyl CpG binding protein 2 0.114605
LMNA lamin A/C 0.114449
CRP C-reactive protein, pentraxin-related 0.110438
CST3 cystatin C 0.10955
IGF1 insulin-like growth factor 1 (somatomedin C) 0.105496
EDN1 endothelin 1 0.099374
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.096367