skin squamous cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A skin carcinoma that has_material_basis_in squamous cells. (Human Disease Ontology, DOID_3151)
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Genes

171 genes co-occuring with the disease skin squamous cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRIM16 tripartite motif containing 16 1.26778
TSSK4 testis-specific serine kinase 4 1.15027
IVL involucrin 1.07236
KRT10 keratin 10, type I 0.986849
DMKN dermokine 0.958705
TP53 tumor protein p53 0.944938
PCNA proliferating cell nuclear antigen 0.940364
TTC34 tetratricopeptide repeat domain 34 0.924213
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.88434
MSH2 mutS homolog 2 0.858952
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.850764
DESI2 desumoylating isopeptidase 2 0.842982
ANKRD6 ankyrin repeat domain 6 0.813462
NKD2 naked cuticle homolog 2 (Drosophila) 0.787623
FAT2 FAT atypical cadherin 2 0.759824
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.749644
PRICKLE2 prickle homolog 2 (Drosophila) 0.74883
KRT4 keratin 4, type II 0.743954
FAT3 FAT atypical cadherin 3 0.733811
MTNR1A melatonin receptor 1A 0.701526
DAAM2 dishevelled associated activator of morphogenesis 2 0.697109
EXOC2 exocyst complex component 2 0.694301
RBP1 retinol binding protein 1, cellular 0.690293
SPRR3 small proline-rich protein 3 0.688692
SPRR1B small proline-rich protein 1B 0.684692
MLH1 mutL homolog 1 0.684292
PRICKLE1 prickle homolog 1 (Drosophila) 0.652089
NKD1 naked cuticle homolog 1 (Drosophila) 0.649323
PIAS4 protein inhibitor of activated STAT, 4 0.647743
FAT4 FAT atypical cadherin 4 0.647743
LOR loricrin 0.637102
CDKN2A cyclin-dependent kinase inhibitor 2A 0.604201
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.60342
S100A6 S100 calcium binding protein A6 0.60225
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.59913
S100A7 S100 calcium binding protein A7 0.594454
DAAM1 dishevelled associated activator of morphogenesis 1 0.591337
KYNU kynureninase 0.574605
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.57305
CLEC2A C-type lectin domain family 2, member A 0.570718
TRIM27 tripartite motif containing 27 0.569163
CTTN cortactin 0.566831
ANGPTL2 angiopoietin-like 2 0.566443
MMP13 matrix metallopeptidase 13 0.560227
CST6 cystatin E/M 0.558285
FOXO4 forkhead box O4 0.555956
HRAS Harvey rat sarcoma viral oncogene homolog 0.555956
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.554015
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.549359
ANXA11 annexin A11 0.546256
WNT5B wingless-type MMTV integration site family, member 5B 0.537731
VANGL2 VANGL planar cell polarity protein 2 0.533861
DVL3 dishevelled segment polarity protein 3 0.529222
VANGL1 VANGL planar cell polarity protein 1 0.524974
FZD6 frizzled class receptor 6 0.522273
TRIM32 tripartite motif containing 32 0.509576
KERA keratocan 0.508424
MMP19 matrix metallopeptidase 19 0.508424
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.503824
RBP2 retinol binding protein 2, cellular 0.499614
MCM5 minichromosome maintenance complex component 5 0.49274
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.487027
MMP9 matrix metallopeptidase 9 0.485125
TFDP3 transcription factor Dp family, member 3 0.483224
PML promyelocytic leukemia 0.480186
DSG3 desmoglein 3 0.469197
DSG1 desmoglein 1 0.468441
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.466928
DVL2 dishevelled segment polarity protein 2 0.460506
KRT17 keratin 17, type I 0.445805
PCSK6 proprotein convertase subtilisin/kexin type 6 0.445429
ANXA6 annexin A6 0.437906
FOXN1 forkhead box N1 0.416147
EGFR epidermal growth factor receptor 0.409787
S100A4 S100 calcium binding protein A4 0.404557
DSG2 desmoglein 2 0.403438
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.402692
WNT11 wingless-type MMTV integration site family, member 11 0.393374
RORA RAR-related orphan receptor A 0.391141
SDC1 syndecan 1 0.390025
MTNR1B melatonin receptor 1B 0.389281
FLG filaggrin 0.388909
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.385936
KRT16 keratin 16, type I 0.384451
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.36741
MSH6 mutS homolog 6 0.361133
POLH polymerase (DNA directed), eta 0.358551
SFRP5 secreted frizzled-related protein 5 0.355972
S100A2 S100 calcium binding protein A2 0.354868
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.351555
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.350452
CSTA cystatin A (stefin A) 0.348246
CD3D CD3d molecule, delta (CD3-TCR complex) 0.346042
CRABP2 cellular retinoic acid binding protein 2 0.345675
EZR ezrin 0.345675
REEP5 receptor accessory protein 5 0.344207
BAK1 BCL2-antagonist/killer 1 0.34384
DCD dermcidin 0.342739
FAT1 FAT atypical cadherin 1 0.342372
KRT15 keratin 15, type I 0.340173
BAD BCL2-associated agonist of cell death 0.339806
TDO2 tryptophan 2,3-dioxygenase 0.337242
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.331025
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.325916
DVL1 dishevelled segment polarity protein 1 0.32373
YAP1 Yes-associated protein 1 0.31464
CD151 CD151 molecule (Raph blood group) 0.308118
CST4 cystatin S 0.302337
STAT2 signal transducer and activator of transcription 2, 113kDa 0.296931
CIB1 calcium and integrin binding 1 (calmyrin) 0.286519
MMP2 matrix metallopeptidase 2 0.284371
CD68 CD68 molecule 0.282225
SFRP4 secreted frizzled-related protein 4 0.281868
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.276158
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.269043
SIRT6 sirtuin 6 0.266558
CD34 CD34 molecule 0.264785
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.261599
S100A9 S100 calcium binding protein A9 0.260891
ANGPTL4 angiopoietin-like 4 0.255594
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.250663
ALK anaplastic lymphoma receptor tyrosine kinase 0.24996
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.248203
BANF1 barrier to autointegration factor 1 0.243995
CALB2 calbindin 2 0.23666
MKI67 marker of proliferation Ki-67 0.233878
FEN1 flap structure-specific endonuclease 1 0.230409
AQP3 aquaporin 3 (Gill blood group) 0.230063
WIF1 WNT inhibitory factor 1 0.225229
SFRP2 secreted frizzled-related protein 2 0.224884
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.222822
IFNA1 interferon, alpha 1 0.222479
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.221108
CD4 CD4 molecule 0.217693
KRT1 keratin 1, type II 0.214975
TCHH trichohyalin 0.210253
HMGA1 high mobility group AT-hook 1 0.207245
FRZB frizzled-related protein 0.205585
MCM2 minichromosome maintenance complex component 2 0.203933
NTSR1 neurotensin receptor 1 (high affinity) 0.201308
ANXA5 annexin A5 0.199356
TPM3 tropomyosin 3 0.199033
CARS cysteinyl-tRNA synthetase 0.197742
LYZ lysozyme 0.197099
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.194548
ZHX2 zinc fingers and homeoboxes 2 0.192971
KLF4 Kruppel-like factor 4 (gut) 0.190476
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.189859
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.183835
SMAD2 SMAD family member 2 0.180937
SORD sorbitol dehydrogenase 0.180367
OSM oncostatin M 0.178682
IFNA2 interferon, alpha 2 0.172544
CYLD cylindromatosis (turban tumor syndrome) 0.169571
DSP desmoplakin 0.165655
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.165217
CSTB cystatin B (stefin B) 0.163523
RDX radixin 0.162707
RPS6 ribosomal protein S6 0.157765
KRT5 keratin 5, type II 0.145296
MB myoglobin 0.143628
MSN moesin 0.138526
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.138373
PI3 peptidase inhibitor 3, skin-derived 0.138123
GP5 glycoprotein V (platelet) 0.138001
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.13796
MMP10 matrix metallopeptidase 10 0.137505
B3GAT1 beta-1,3-glucuronyltransferase 1 0.137476
AREG amphiregulin 0.136746
XPC xeroderma pigmentosum, complementation group C 0.134559
SMO smoothened, frizzled class receptor 0.134299