situs inversus Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [LS]. (Human Disease Ontology, DOID_758)
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Genes

165 genes co-occuring with the disease situs inversus in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INVS inversin 2.30137
DNAH5 dynein, axonemal, heavy chain 5 2.06307
DNAI1 dynein, axonemal, intermediate chain 1 1.96051
NPHP3 nephronophthisis 3 (adolescent) 1.72274
DNAH11 dynein, axonemal, heavy chain 11 1.69269
DNAH9 dynein, axonemal, heavy chain 9 1.67683
GDF1 growth differentiation factor 1 1.57601
ZIC3 Zic family member 3 1.53304
DNAI2 dynein, axonemal, intermediate chain 2 1.47638
CFAP53 cilia and flagella associated protein 53 1.42454
MYO1D myosin ID 1.42367
SEPT7P2 septin 7 pseudogene 2 1.41709
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.40351
DNAL4 dynein, axonemal, light chain 4 1.39957
SETMAR SET domain and mariner transposase fusion gene 1.39302
DNAAF1 dynein, axonemal, assembly factor 1 1.38516
MNS1 meiosis-specific nuclear structural 1 1.37599
CCDC39 coiled-coil domain containing 39 1.35333
CEP70 centrosomal protein 70kDa 1.34984
NPHP1 nephronophthisis 1 (juvenile) 1.34243
LEFTY2 left-right determination factor 2 1.30969
TCTE3 t-complex-associated-testis-expressed 3 1.27257
FOXJ1 forkhead box J1 1.2508
MEGF8 multiple EGF-like-domains 8 1.22692
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.20137
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 1.1473
LZTFL1 leucine zipper transcription factor-like 1 1.13882
ARMC4 armadillo repeat containing 4 1.1173
SPATA4 spermatogenesis associated 4 1.11687
IQCB1 IQ motif containing B1 1.10175
RSPH9 radial spoke head 9 homolog (Chlamydomonas) 1.09755
PLXNB2 plexin B2 1.09629
DNAH1 dynein, axonemal, heavy chain 1 1.0795
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 1.0753
SPAG17 sperm associated antigen 17 1.07488
RFX3 regulatory factor X, 3 (influences HLA class II expression) 1.06186
PKD1L1 polycystic kidney disease 1 like 1 1.03704
PITX2 paired-like homeodomain 2 1.01512
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.01132
RFX4 regulatory factor X, 4 (influences HLA class II expression) 1.00879
CCDC40 coiled-coil domain containing 40 0.996549
LRRC6 leucine rich repeat containing 6 0.986849
GLOD4 glyoxalase domain containing 4 0.9839
ADRA1B adrenoceptor alpha 1B 0.978426
KIF3A kinesin family member 3A 0.967502
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.955779
NME7 NME/NM23 family member 7 0.930828
SEC24B SEC24 family member B 0.920911
MED13L mediator complex subunit 13-like 0.904854
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.904854
SPAG16 sperm associated antigen 16 0.900335
ANKRD6 ankyrin repeat domain 6 0.897051
ADRA1A adrenoceptor alpha 1A 0.882701
NME8 NME/NM23 family member 8 0.877786
NPHP4 nephronophthisis 4 0.874509
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.863046
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.855268
BANP BTG3 associated nuclear protein 0.847078
HES7 hes family bHLH transcription factor 7 0.827409
NEK9 NIMA-related kinase 9 0.805667
TMEM216 transmembrane protein 216 0.801564
ARL2 ADP-ribosylation factor-like 2 0.800744
SPAG6 sperm associated antigen 6 0.799923
CFC1 cripto, FRL-1, cryptic family 1 0.789672
RPGR retinitis pigmentosa GTPase regulator 0.788852
TNPO1 transportin 1 0.787623
HYDIN HYDIN, axonemal central pair apparatus protein 0.787213
DVL1 dishevelled segment polarity protein 1 0.772479
SCRIB scribbled planar cell polarity protein 0.766759
GDF3 growth differentiation factor 3 0.752085
PROP1 PROP paired-like homeobox 1 0.737865
ARL3 ADP-ribosylation factor-like 3 0.734622
DNAH14 dynein, axonemal, heavy chain 14 0.719654
DNAH12 dynein, axonemal, heavy chain 12 0.719654
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.71925
CEP290 centrosomal protein 290kDa 0.709975
NODAL nodal growth differentiation factor 0.709975
SHH sonic hedgehog 0.702732
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.699116
UVRAG UV radiation resistance associated 0.698715
SEC63 SEC63 homolog (S. cerevisiae) 0.692296
PTPRB protein tyrosine phosphatase, receptor type, B 0.668345
ACVR2B activin A receptor, type IIB 0.66199
TTC8 tetratricopeptide repeat domain 8 0.661197
MKS1 Meckel syndrome, type 1 0.651694
CDON cell adhesion associated, oncogene regulated 0.641827
RAB23 RAB23, member RAS oncogene family 0.63907
ANK1 ankyrin 1, erythrocytic 0.633169
TMEM67 transmembrane protein 67 0.632777
MIRLET7E microRNA let-7e 0.626103
CHRD chordin 0.622575
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.616703
VANGL2 VANGL planar cell polarity protein 2 0.613574
GDF6 growth differentiation factor 6 0.60225
ACVR1B activin A receptor, type IB 0.58005
NXN nucleoredoxin 0.575772
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.570329
DYX1C1 dyslexia susceptibility 1 candidate 1 0.569941
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.569941
APOPT1 apoptogenic 1, mitochondrial 0.568386
IFT88 intraflagellar transport 88 0.566443
HAVCR1 hepatitis A virus cellular receptor 1 0.564889
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.564112
TEF thyrotrophic embryonic factor 0.548583
POLB polymerase (DNA directed), beta 0.543155
POU1F1 POU class 1 homeobox 1 0.53657
MIR25 microRNA 25 0.523045
THEM5 thioesterase superfamily member 5 0.520731
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.513033
ZMYND10 zinc finger, MYND-type containing 10 0.510344
POLL polymerase (DNA directed), lambda 0.509576
PCSK6 proprotein convertase subtilisin/kexin type 6 0.48893
PRKCSH protein kinase C substrate 80K-H 0.488549
GLIS2 GLIS family zinc finger 2 0.480186
KLF10 Kruppel-like factor 10 0.478289
SMO smoothened, frizzled class receptor 0.476014
YIPF1 Yip1 domain family, member 1 0.471846
RORA RAR-related orphan receptor A 0.467684
FRY furry homolog (Drosophila) 0.46655
SEPT2 septin 2 0.463149
FOXD3 forkhead box D3 0.462016
NEK8 NIMA-related kinase 8 0.458996
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.455601
MIR93 microRNA 93 0.452208
MECOM MDS1 and EVI1 complex locus 0.449194
PTCH1 patched 1 0.442042
NPTXR neuronal pentraxin receptor 0.42739
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.409787
MKKS McKusick-Kaufman syndrome 0.403811
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.398962
NKX2-5 NK2 homeobox 5 0.381852
TGFB1 transforming growth factor, beta 1 0.381481
SEPT5 septin 5 0.37555
CHD7 chromodomain helicase DNA binding protein 7 0.323002
FGF10 fibroblast growth factor 10 0.319363
MYO1C myosin IC 0.311014
CRIP1 cysteine-rich protein 1 (intestinal) 0.304142
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.303059
CSK c-src tyrosine kinase 0.298011
TBX1 T-box 1 0.283297
FGF8 fibroblast growth factor 8 (androgen-induced) 0.277227
RFXANK regulatory factor X-associated ankyrin-containing protein 0.275801
EFS embryonal Fyn-associated substrate 0.275445
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.270464
LIG4 ligase IV, DNA, ATP-dependent 0.257711
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.242245
HAND2 heart and neural crest derivatives expressed 2 0.232489
ADRA1D adrenoceptor alpha 1D 0.232489
WNT1 wingless-type MMTV integration site family, member 1 0.230755
NTN1 netrin 1 0.229024
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.224196
EDNRA endothelin receptor type A 0.220766
H3F3A H3 histone, family 3A 0.218034
H3F3B H3 histone, family 3B (H3.3B) 0.218034
FTO fat mass and obesity associated 0.211261
GLI2 GLI family zinc finger 2 0.20229
SUMF2 sulfatase modifying factor 2 0.188632
WNT3A wingless-type MMTV integration site family, member 3A 0.18472
FST follistatin 0.180937
MYO1E myosin IE 0.180937
UMOD uromodulin 0.177576
EPHA2 EPH receptor A2 0.168617
HEXB hexosaminidase B (beta polypeptide) 0.165435
DNAH8 dynein, axonemal, heavy chain 8 0.165001
CRHR1 corticotropin releasing hormone receptor 1 0.162908