site of double-strand break Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix. (Gene Ontology, GO_0035861)
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Genes

15 proteins localized to the site of double-strand break cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NBN nibrin 0.663342
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.663342
PARP3 poly (ADP-ribose) polymerase family, member 3 0.663342
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.663342
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.663342
RNF169 ring finger protein 169 0.663342
APLF aprataxin and PNKP like factor 0.663342
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.663342
ATF2 activating transcription factor 2 0.663342
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.663342
VCP valosin containing protein 0.663342
RAD50 RAD50 homolog (S. cerevisiae) 0.663342
H2AFX H2A histone family, member X 0.663342
PHF1 PHD finger protein 1 0.663342
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.03318