| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the sirolimus-6967 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARL4D | ADP-ribosylation factor-like 4D |
| AURKA | aurora kinase A |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| CADM4 | cell adhesion molecule 4 |
| CCNG2 | cyclin G2 |
| CDC25C | cell division cycle 25C |
| CDK12 | cyclin-dependent kinase 12 |
| CDK20 | cyclin-dependent kinase 20 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLDN15 | claudin 15 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EFNA3 | ephrin-A3 |
| EGR1 | early growth response 1 |
| ESR1 | estrogen receptor 1 |
| ESRRA | estrogen-related receptor alpha |
| FAM155A | family with sequence similarity 155, member A |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FILIP1L | filamin A interacting protein 1-like |
| GAMT | guanidinoacetate N-methyltransferase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC4 | glypican 4 |
| GPR15 | G protein-coupled receptor 15 |
| GPR153 | G protein-coupled receptor 153 |
| GPR87 | G protein-coupled receptor 87 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ITM2C | integral membrane protein 2C |
| JRK | Jrk homolog (mouse) |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIF5C | kinesin family member 5C |
| KLHL24 | kelch-like family member 24 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNA | lamin A/C |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MED12 | mediator complex subunit 12 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MOB3B | MOB kinase activator 3B |
| MR1 | major histocompatibility complex, class I-related |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYO15B | myosin XVB |
| NDRG2 | NDRG family member 2 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCDHB3 | protocadherin beta 3 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK3 | polo-like kinase 3 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POPDC3 | popeye domain containing 3 |
| POU5F1B | POU class 5 homeobox 1B |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RGS5 | regulator of G-protein signaling 5 |
| RNF122 | ring finger protein 122 |
| RNF170 | ring finger protein 170 |
| RNF19B | ring finger protein 19B |
| RPS3A | ribosomal protein S3A |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RTN2 | reticulon 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH3D21 | SH3 domain containing 21 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SSPN | sarcospan |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TXNIP | thioredoxin interacting protein |
| VPRBP | Vpr (HIV-1) binding protein |
| VPS9D1 | VPS9 domain containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF571 | zinc finger protein 571 |
| ZNF580 | zinc finger protein 580 |
| ZNF589 | zinc finger protein 589 |
| ZNF606 | zinc finger protein 606 |
| ZNF750 | zinc finger protein 750 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARRB2 | arrestin, beta 2 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| AUNIP | aurora kinase A and ninein interacting protein |
| BAK1 | BCL2-antagonist/killer 1 |
| BARD1 | BRCA1 associated RING domain 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CHSY1 | chondroitin sulfate synthase 1 |
| COPS7B | COP9 signalosome subunit 7B |
| DCP1A | decapping mRNA 1A |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAL4 | dynein, axonemal, light chain 4 |
| DTWD1 | DTW domain containing 1 |
| ELMO3 | engulfment and cell motility 3 |
| FAM57A | family with sequence similarity 57, member A |
| FBXO31 | F-box protein 31 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FMO4 | flavin containing monooxygenase 4 |
| FOSL1 | FOS-like antigen 1 |
| FOXJ2 | forkhead box J2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| GRAMD4 | GRAM domain containing 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IFT81 | intraflagellar transport 81 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JMJD4 | jumonji domain containing 4 |
| KLC2 | kinesin light chain 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MEIS1 | Meis homeobox 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICALL2 | MICAL-like 2 |
| MIR22HG | MIR22 host gene |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MSX1 | msh homeobox 1 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NPY5R | neuropeptide Y receptor Y5 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| ORC1 | origin recognition complex, subunit 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| POMZP3 | POM121 and ZP3 fusion |
| POR | P450 (cytochrome) oxidoreductase |
| PPAN | peter pan homolog (Drosophila) |
| PSPH | phosphoserine phosphatase |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RBBP5 | retinoblastoma binding protein 5 |
| RBM38 | RNA binding motif protein 38 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A4 | S100 calcium binding protein A4 |
| SART1 | squamous cell carcinoma antigen recognized by T cells |
| SERTAD3 | SERTA domain containing 3 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNHG3 | small nucleolar RNA host gene 3 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TGDS | TDP-glucose 4,6-dehydratase |
| THAP4 | THAP domain containing 4 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UNKL | unkempt family zinc finger-like |
| WDR44 | WD repeat domain 44 |
| WDR46 | WD repeat domain 46 |
| ZNF408 | zinc finger protein 408 |
| ZNF586 | zinc finger protein 586 |
