Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the sirolimus-6167 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTN2 | actinin, alpha 2 |
ACTN3 | actinin, alpha 3 (gene/pseudogene) |
APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
ASIC4 | acid sensing (proton gated) ion channel family member 4 |
BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
BCL2L1 | BCL2-like 1 |
BIN1 | bridging integrator 1 |
BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
CCSER2 | coiled-coil serine-rich protein 2 |
CDK10 | cyclin-dependent kinase 10 |
CHERP | calcium homeostasis endoplasmic reticulum protein |
CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
CNTD2 | cyclin N-terminal domain containing 2 |
COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
COL10A1 | collagen, type X, alpha 1 |
CTSF | cathepsin F |
DCAF17 | DDB1 and CUL4 associated factor 17 |
DLG3 | discs, large homolog 3 (Drosophila) |
DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 |
EFNA3 | ephrin-A3 |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
F5 | coagulation factor V (proaccelerin, labile factor) |
FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
FCAR | Fc fragment of IgA receptor |
FGF9 | fibroblast growth factor 9 |
FGFR1 | fibroblast growth factor receptor 1 |
FSHB | follicle stimulating hormone, beta polypeptide |
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
GAL | galanin/GMAP prepropeptide |
GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
GAS1 | growth arrest-specific 1 |
GFRA1 | GDNF family receptor alpha 1 |
GLRA1 | glycine receptor, alpha 1 |
GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
GPM6B | glycoprotein M6B |
HHLA1 | HERV-H LTR-associating 1 |
HIST1H4E | histone cluster 1, H4e |
HOXA4 | homeobox A4 |
HOXB5 | homeobox B5 |
ING1 | inhibitor of growth family, member 1 |
ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
KIF3C | kinesin family member 3C |
KSR1 | kinase suppressor of ras 1 |
MAGEH1 | melanoma antigen family H1 |
MDFI | MyoD family inhibitor |
MED25 | mediator complex subunit 25 |
MERTK | MER proto-oncogene, tyrosine kinase |
MR1 | major histocompatibility complex, class I-related |
MSR1 | macrophage scavenger receptor 1 |
MYH14 | myosin, heavy chain 14, non-muscle |
NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
NF1 | neurofibromin 1 |
NIPAL2 | NIPA-like domain containing 2 |
NOD2 | nucleotide-binding oligomerization domain containing 2 |
NPPA | natriuretic peptide A |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PAX4 | paired box 4 |
PDE10A | phosphodiesterase 10A |
PLSCR3 | phospholipid scramblase 3 |
PLXNB3 | plexin B3 |
PMEL | premelanosome protein |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
PRSS53 | protease, serine, 53 |
PTCRA | pre T-cell antigen receptor alpha |
PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
RAB13 | RAB13, member RAS oncogene family |
RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
REC8 | REC8 meiotic recombination protein |
RFPL1 | ret finger protein-like 1 |
RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RTEL1 | regulator of telomere elongation helicase 1 |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SCN5A | sodium channel, voltage gated, type V alpha subunit |
SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SETBP1 | SET binding protein 1 |
SFN | stratifin |
SKAP1 | src kinase associated phosphoprotein 1 |
SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
SPARCL1 | SPARC-like 1 (hevin) |
SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
SYT5 | synaptotagmin V |
TAPT1 | transmembrane anterior posterior transformation 1 |
TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
THBS1 | thrombospondin 1 |
TNPO2 | transportin 2 |
TRGV5 | T cell receptor gamma variable 5 |
UPP1 | uridine phosphorylase 1 |
VASH1 | vasohibin 1 |
ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
ZNF444 | zinc finger protein 444 |
Symbol | Name |
---|---|
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ACPP | acid phosphatase, prostate |
ADGRG2 | adhesion G protein-coupled receptor G2 |
AICDA | activation-induced cytidine deaminase |
ATAT1 | alpha tubulin acetyltransferase 1 |
BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
BBC3 | BCL2 binding component 3 |
BCAS3 | breast carcinoma amplified sequence 3 |
BGLAP | bone gamma-carboxyglutamate (gla) protein |
C4ORF29 | chromosome 4 open reading frame 29 |
CAPN15 | calpain 15 |
CCDC121 | coiled-coil domain containing 121 |
CCDC69 | coiled-coil domain containing 69 |
CCL21 | chemokine (C-C motif) ligand 21 |
CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
CDO1 | cysteine dioxygenase type 1 |
CDR2L | cerebellar degeneration-related protein 2-like |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
CRY2 | cryptochrome circadian clock 2 |
CTH | cystathionine gamma-lyase |
CTSG | cathepsin G |
CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
DDN | dendrin |
DFNA5 | deafness, autosomal dominant 5 |
EDAR | ectodysplasin A receptor |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
FCHO1 | FCH domain only 1 |
FGL1 | fibrinogen-like 1 |
FSTL3 | follistatin-like 3 (secreted glycoprotein) |
GAA | glucosidase, alpha; acid |
GJA9 | gap junction protein, alpha 9, 59kDa |
GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
GPATCH3 | G patch domain containing 3 |
GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
HDAC11 | histone deacetylase 11 |
HIST1H3G | histone cluster 1, H3g |
HOXA1 | homeobox A1 |
HOXC8 | homeobox C8 |
HPSE | heparanase |
HTRA1 | HtrA serine peptidase 1 |
IQSEC2 | IQ motif and Sec7 domain 2 |
KIAA0319L | KIAA0319-like |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
KRT8P12 | keratin 8 pseudogene 12 |
LAMB3 | laminin, beta 3 |
LRRC20 | leucine rich repeat containing 20 |
MOB3B | MOB kinase activator 3B |
MVP | major vault protein |
N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
NPFFR1 | neuropeptide FF receptor 1 |
NPIPB3 | nuclear pore complex interacting protein family, member B3 |
PARP16 | poly (ADP-ribose) polymerase family, member 16 |
PFN2 | profilin 2 |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
POTEKP | POTE ankyrin domain family, member K, pseudogene |
PPCS | phosphopantothenoylcysteine synthetase |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
PRKCE | protein kinase C, epsilon |
PRY | PTPN13-like, Y-linked |
PSAT1 | phosphoserine aminotransferase 1 |
RAB3A | RAB3A, member RAS oncogene family |
RWDD2A | RWD domain containing 2A |
SIRT2 | sirtuin 2 |
SLC16A6 | solute carrier family 16, member 6 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SMR3A | submaxillary gland androgen regulated protein 3A |
SMYD5 | SMYD family member 5 |
SNX29P2 | sorting nexin 29 pseudogene 2 |
SOX21 | SRY (sex determining region Y)-box 21 |
SPATA20 | spermatogenesis associated 20 |
SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STK16 | serine/threonine kinase 16 |
STXBP5L | syntaxin binding protein 5-like |
TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
TAS2R1 | taste receptor, type 2, member 1 |
TMEM120B | transmembrane protein 120B |
TMEM57 | transmembrane protein 57 |
TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
TRAF1 | TNF receptor-associated factor 1 |
TUBB2A | tubulin, beta 2A class IIa |
USB1 | U6 snRNA biogenesis 1 |
VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
WDR25 | WD repeat domain 25 |
ZBTB25 | zinc finger and BTB domain containing 25 |
ZNF177 | zinc finger protein 177 |
ZNF345 | zinc finger protein 345 |
ZNF696 | zinc finger protein 696 |
ZNF747 | zinc finger protein 747 |
ZNF76 | zinc finger protein 76 |
ZNF862 | zinc finger protein 862 |
ZSCAN18 | zinc finger and SCAN domain containing 18 |