simplex Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

176 genes co-occuring with the biological term simplex in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTG1 actin gamma 1
ADORA1 adenosine A1 receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALYREF Aly/REF export factor
ANKH ANKH inorganic pyrophosphate transport regulator
APCDD1 adenomatosis polyposis coli down-regulated 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASF1A anti-silencing function 1A histone chaperone
ATR ATR serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAG3 BCL2-associated athanogene 3
BID BH3 interacting domain death agonist
C21ORF91 chromosome 21 open reading frame 91
CAPN1 calpain 1, (mu/I) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDSN corneodesmosin
CFL1 cofilin 1 (non-muscle)
CHMP3 charged multivesicular body protein 3
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN1 claudin 1
CLOCK clock circadian regulator
CLU clusterin
COX7B cytochrome c oxidase subunit VIIb
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREBZF CREB/ATF bZIP transcription factor
CST3 cystatin C
CSTA cystatin A (stefin A)
CTCF CCCTC-binding factor (zinc finger protein)
CTSH cathepsin H
CTSL cathepsin L
CTSS cathepsin S
CYTIP cytohesin 1 interacting protein
DAXX death-domain associated protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNM1 dynamin 1
DNM2 dynamin 2
DST dystonin
EGR1 early growth response 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
EIF4H eukaryotic translation initiation factor 4H
ERBB2 erb-b2 receptor tyrosine kinase 2
EXPH5 exophilin 5
FEN1 flap structure-specific endonuclease 1
FLG filaggrin
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HCFC1 host cell factor C1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HIPK2 homeodomain interacting protein kinase 2
HIST2H2BE histone cluster 2, H2be
HIST2H4A histone cluster 2, H4a
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HSPA8 heat shock 70kDa protein 8
IFI16 interferon, gamma-inducible protein 16
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IGF2R insulin-like growth factor 2 receptor
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL13 interleukin 13
IL25 interleukin 25
IL4 interleukin 4
INSM1 insulinoma-associated 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
ITGB8 integrin, beta 8
KLF15 Kruppel-like factor 15
KLHL24 kelch-like family member 24
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LIFR leukemia inhibitory factor receptor alpha
LIPH lipase, member H
LMNA lamin A/C
LMNB1 lamin B1
LPAR6 lysophosphatidic acid receptor 6
LUM lumican
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MARCO macrophage receptor with collagenous structure
MITF microphthalmia-associated transcription factor
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MON1B MON1 secretory trafficking family member B
MSN moesin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NCL nucleolin
NET1 neuroepithelial cell transforming 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP3 NLR family, pyrin domain containing 3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NXF1 nuclear RNA export factor 1
PAX3 paired box 3
PDZD8 PDZ domain containing 8
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PKLR pyruvate kinase, liver and RBC
PLEC plectin
PML promyelocytic leukemia
POLH polymerase (DNA directed), eta
PRKD1 protein kinase D1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB1A RAB1A, member RAS oncogene family
RAB1B RAB1B, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB43 RAB43, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RCOR1 REST corepressor 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
SAMHD1 SAM domain and HD domain 1
SAP30BP SAP30 binding protein
SELPLG selectin P ligand
SENP1 SUMO1/sentrin specific peptidase 1
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SNAI2 snail family zinc finger 2
SNRPE small nuclear ribonucleoprotein polypeptide E
SOCS1 suppressor of cytokine signaling 1
SP1 Sp1 transcription factor
SP100 SP100 nuclear antigen
SPDEF SAM pointed domain containing ETS transcription factor
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SSH1 slingshot protein phosphatase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT4 signal transducer and activator of transcription 4
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM5 transglutaminase 5
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR9 toll-like receptor 9
TMLHE trimethyllysine hydroxylase, epsilon
TNF tumor necrosis factor
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TRAF3 TNF receptor-associated factor 3
TSC22D3 TSC22 domain family, member 3
UNC93B1 unc-93 homolog B1 (C. elegans)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VIM vimentin
XPO1 exportin 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6