signet ring cell adenocarcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An adenocarcinoma that derives_from epithelial cells originating in glandular tissue, which have signet ring appearance. (Human Disease Ontology, DOID_3493)
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Genes

106 genes co-occuring with the disease signet ring cell adenocarcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MUC2 mucin 2, oligomeric mucus/gel-forming 1.69088
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.51106
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.49043
MUC6 mucin 6, oligomeric mucus/gel-forming 1.47989
KRT20 keratin 20, type I 1.44782
KRT7 keratin 7, type II 1.44167
FGF6 fibroblast growth factor 6 1.39127
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.38909
TMEM207 transmembrane protein 207 1.2356
PIP prolactin-induced protein 1.19186
MUC1 mucin 1, cell surface associated 1.15453
CDX2 caudal type homeobox 2 1.13289
TUB tubby bipartite transcription factor 1.10343
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.899924
KRT8 keratin 8, type II 0.872872
CLDN18 claudin 18 0.864274
KLF7 Kruppel-like factor 7 (ubiquitous) 0.85404
TRAK1 trafficking protein, kinesin binding 1 0.837246
COL14A1 collagen, type XIV, alpha 1 0.829049
TP53 tumor protein p53 0.817565
TRIM47 tripartite motif containing 47 0.815514
RAB33A RAB33A, member RAS oncogene family 0.812232
MUC4 mucin 4, cell surface associated 0.80936
KRT5 keratin 5, type II 0.788033
KLK3 kallikrein-related peptidase 3 0.780251
WNT2B wingless-type MMTV integration site family, member 2B 0.760231
CTSE cathepsin E 0.745985
ACPP acid phosphatase, prostate 0.717635
STARD3 StAR-related lipid transfer (START) domain containing 3 0.707157
NOXO1 NADPH oxidase organizer 1 0.692296
CHRDL2 chordin-like 2 0.682294
PGAP3 post-GPI attachment to proteins 3 0.677105
WNT8B wingless-type MMTV integration site family, member 8B 0.670333
NKX2-1 NK2 homeobox 1 0.658818
TCAP titin-cap 0.652089
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.593285
KRT14 keratin 14, type I 0.580828
WNT2 wingless-type MMTV integration site family member 2 0.58005
KRAS Kirsten rat sarcoma viral oncogene homolog 0.574994
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.564889
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.561004
PTPRB protein tyrosine phosphatase, receptor type, B 0.523045
LIN7A lin-7 homolog A (C. elegans) 0.517265
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.513417
PIR pirin (iron-binding nuclear protein) 0.490454
SCGB2A1 secretoglobin, family 2A, member 1 0.487407
HDLBP high density lipoprotein binding protein 0.480566
JUP junction plakoglobin 0.479427
FAP fibroblast activation protein, alpha 0.452208
TCEA1 transcription elongation factor A (SII), 1 0.447687
EGFL7 EGF-like-domain, multiple 7 0.445805
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.442042
WWTR1 WW domain containing transcription regulator 1 0.433772
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.430017
PLA2G2D phospholipase A2, group IID 0.429642
ATOH1 atonal homolog 1 (Drosophila) 0.42814
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.422515
HRAS Harvey rat sarcoma viral oncogene homolog 0.411283
MACC1 metastasis associated in colon cancer 1 0.409414
CDKN2A cyclin-dependent kinase inhibitor 2A 0.400826
ERBB2 erb-b2 receptor tyrosine kinase 2 0.388909
SYP synaptophysin 0.379626
ESR1 estrogen receptor 1 0.371477
GAST gastrin 0.355235
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.332121
RORA RAR-related orphan receptor A 0.329565
SDC1 syndecan 1 0.328469
NADK NAD kinase 0.32774
SP3 Sp3 transcription factor 0.313552
PDPN podoplanin 0.305948
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.289744
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.289027
REG1A regenerating islet-derived 1 alpha 0.287952
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.285086
EPCAM epithelial cell adhesion molecule 0.282225
RFC2 replication factor C (activator 1) 2, 40kDa 0.279367
VEGFA vascular endothelial growth factor A 0.272597
MET MET proto-oncogene, receptor tyrosine kinase 0.264077
TAZ tafazzin 0.260538
MLH1 mutL homolog 1 0.259124
ERBB3 erb-b2 receptor tyrosine kinase 3 0.253127
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.242595
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.236312
CNN1 calponin 1, basic, smooth muscle 0.235964
MFGE8 milk fat globule-EGF factor 8 protein 0.232489
CXCL14 chemokine (C-X-C motif) ligand 14 0.231102
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.22937
FHIT fragile histidine triad 0.229024
PGC progastricsin (pepsinogen C) 0.218715
CD8B CD8b molecule 0.210253
CD68 CD68 molecule 0.207912
CHGA chromogranin A 0.206913
ENO2 enolase 2 (gamma, neuronal) 0.204923
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.204593
MAP2K3 mitogen-activated protein kinase kinase 3 0.201635
NAPSA napsin A aspartic peptidase 0.200656
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.190786
RER1 retention in endoplasmic reticulum sorting receptor 1 0.188022
CALB2 calbindin 2 0.181798
WWOX WW domain containing oxidoreductase 0.177029
SMAD4 SMAD family member 4 0.176485
IGLV2-14 immunoglobulin lambda variable 2-14 0.167224
NDRG1 N-myc downstream regulated 1 0.162707
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.161912
HNF4A hepatocyte nuclear factor 4, alpha 0.161139
PLA2G10 phospholipase A2, group X 0.157765