signal transduction by p53 class mediator Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein. (Gene Ontology, GO_0072331)
External Link http://amigo.geneontology.org/amigo/term/GO:0072331
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Genes

127 genes participating in the signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AEN apoptosis enhancing nuclease
ATM ATM serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAG6 BCL2-associated athanogene 6
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCL3 B-cell CLL/lymphoma 3
BOK BCL2-related ovarian killer
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDIP1 cell death-inducing p53 target 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DDIT4 DNA-damage-inducible transcript 4
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F7 E2F transcription factor 7
EDA2R ectodysplasin A2 receptor
EP300 E1A binding protein p300
FHIT fragile histidine triad
FOXM1 forkhead box M1
FOXO3 forkhead box O3
GML glycosylphosphatidylinositol anchored molecule like
GREM1 gremlin 1, DAN family BMP antagonist
GTSE1 G-2 and S-phase expressed 1
HINT1 histidine triad nucleotide binding protein 1
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
IFI16 interferon, gamma-inducible protein 16
ING4 inhibitor of growth family, member 4
JMY junction mediating and regulatory protein, p53 cofactor
KAT5 K(lysine) acetyltransferase 5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MSH2 mutS homolog 2
MUC1 mucin 1, cell surface associated
MYBBP1A MYB binding protein (P160) 1a
MYO6 myosin VI
NBN nibrin
NDRG1 N-myc downstream regulated 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PERP PERP, TP53 apoptosis effector
PGAP2 post-GPI attachment to proteins 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIDD1 p53-induced death domain protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PYCARD PYD and CARD domain containing
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SHISA5 shisa family member 5
SIRT1 sirtuin 1
SNW1 SNW domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SP100 SP100 nuclear antigen
STK11 serine/threonine kinase 11
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM109 transmembrane protein 109
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TP73 tumor protein p73
TRIAP1 TP53 regulated inhibitor of apoptosis 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
USP10 ubiquitin specific peptidase 10
USP28 ubiquitin specific peptidase 28
WWOX WW domain containing oxidoreductase
ZNF385B zinc finger protein 385B