shock Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

337 genes co-occuring with the biological term shock in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADM adrenomedullin
ADORA3 adenosine A3 receptor
ADRA1A adrenoceptor alpha 1A
ADRB2 adrenoceptor beta 2, surface
AGTRAP angiotensin II receptor-associated protein
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
ALPI alkaline phosphatase, intestinal
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
AOC3 amine oxidase, copper containing 3
APLN apelin
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
ATF4 activating transcription factor 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG7 autophagy related 7
ATXN3 ataxin 3
AVP arginine vasopressin
AZU1 azurocidin 1
BAG3 BCL2-associated athanogene 3
BGN biglycan
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
C11ORF73 chromosome 11 open reading frame 73
C5AR1 complement component 5a receptor 1
C8ORF4 chromosome 8 open reading frame 4
CALCA calcitonin-related polypeptide alpha
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR3 chemokine (C-C motif) receptor 3
CD40LG CD40 ligand
CD6 CD6 molecule
CDC37 cell division cycle 37
CDK1 cyclin-dependent kinase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CFB complement factor B
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CHEK1 checkpoint kinase 1
CHGA chromogranin A
CIITA class II, major histocompatibility complex, transactivator
CIRBP cold inducible RNA binding protein
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLU clusterin
CMA1 chymase 1, mast cell
COMT catechol-O-methyltransferase
CPB2 carboxypeptidase B2 (plasma)
CRH corticotropin releasing hormone
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CSF3 colony stimulating factor 3 (granulocyte)
CST3 cystatin C
CTGF connective tissue growth factor
CTSC cathepsin C
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF4E eukaryotic translation initiation factor 4E
ELAVL1 ELAV like RNA binding protein 1
ENDOG endonuclease G
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FAM162A family with sequence similarity 162, member A
FASLG Fas ligand (TNF superfamily, member 6)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXL2 forkhead box L2
FUS FUS RNA binding protein
GCH1 GTP cyclohydrolase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GHRL ghrelin/obestatin prepropeptide
GPX1 glutathione peroxidase 1
H2AFX H2A histone family, member X
HAVCR1 hepatitis A virus cellular receptor 1
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H3C histone cluster 2, H3c
HIST2H4A histone cluster 2, H4a
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HSF4 heat shock transcription factor 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AA2P heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPB8 heat shock 22kDa protein 8
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL18 interleukin 18
IL19 interleukin 19
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL33 interleukin 33
IL6 interleukin 6
ILK integrin-linked kinase
IRAK1 interleukin-1 receptor-associated kinase 1
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB4 integrin, beta 4
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KLF6 Kruppel-like factor 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KNG1 kininogen 1
KRT18 keratin 18, type I
LCN2 lipocalin 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LNPEP leucyl/cystinyl aminopeptidase
LONP1 lon peptidase 1, mitochondrial
LRP1 low density lipoprotein receptor-related protein 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MERTK MER proto-oncogene, tyrosine kinase
MFAP5 microfibrillar associated protein 5
MFRP membrane frizzled-related protein
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR122 microRNA 122
MIR1908 microRNA 1908
MIR223 microRNA 223
MIR34A microRNA 34a
MIR499A microRNA 499a
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRPS12 mitochondrial ribosomal protein S12
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH9 myosin, heavy chain 9, non-muscle
NCOA6 nuclear receptor coactivator 6
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPC1L1 NPC1-like 1
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
OLA1 Obg-like ATPase 1
OSTC oligosaccharyltransferase complex subunit (non-catalytic)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PDCD1 programmed cell death 1
PDIA2 protein disulfide isomerase family A, member 2
PENK proenkephalin
PGLYRP1 peptidoglycan recognition protein 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PPID peptidylprolyl isomerase D
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCI protein kinase C, iota
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSIP1 PC4 and SFRS1 interacting protein 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGDR2 prostaglandin D2 receptor 2
PTGES prostaglandin E synthase
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
PYCARD PYD and CARD domain containing
RAD51 RAD51 recombinase
RCOR1 REST corepressor 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS3 regulator of G-protein signaling 3
RNF207 ring finger protein 207
RNF7 ring finger protein 7
RPA1 replication protein A1, 70kDa
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SDC1 syndecan 1
SELE selectin E
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIGLEC9 sialic acid binding Ig-like lectin 9
SIRT1 sirtuin 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNIP1 Smad nuclear interacting protein 1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SPDEF SAM pointed domain containing ETS transcription factor
SRY sex determining region Y
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STK11 serine/threonine kinase 11
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARDBP TAR DNA binding protein
TARP TCR gamma alternate reading frame protein
TERT telomerase reverse transcriptase
TF transferrin
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THEM4 thioesterase superfamily member 4
THPO thrombopoietin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNK2 tyrosine kinase, non-receptor, 2
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
TPT1 tumor protein, translationally-controlled 1
TRAP1 TNF receptor-associated protein 1
TRD T cell receptor delta locus
TREM1 triggering receptor expressed on myeloid cells 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TUBA1B tubulin, alpha 1b
TXN thioredoxin
TXNIP thioredoxin interacting protein
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VWF von Willebrand factor
WT1 Wilms tumor 1
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFAND2A zinc finger, AN1-type domain 2A