sexual dysfunction Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

184 genes co-occuring with the disease sexual dysfunction in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDE5A phosphodiesterase 5A, cGMP-specific 2.21858
KLK3 kallikrein-related peptidase 3 1.80066
SHBG sex hormone-binding globulin 1.80021
PRL prolactin 1.54098
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.52028
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.14305
BCR breakpoint cluster region 1.09587
ADRA1D adrenoceptor alpha 1D 1.07782
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.04672
AR androgen receptor 1.0383
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 1.03451
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.02313
ACE angiotensin I converting enzyme 0.975482
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.948269
INS insulin 0.902799
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.899924
ATG4C autophagy related 4C, cysteine peptidase 0.88434
PAPLN papilin, proteoglycan-like sulfated glycoprotein 0.866731
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.861409
MC4R melanocortin 4 receptor 0.848716
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.847898
HFE hemochromatosis 0.840525
BMP2K BMP2 inducible kinase 0.816745
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.80977
APOLD1 apolipoprotein L domain containing 1 0.779023
NOS3 nitric oxide synthase 3 (endothelial cell) 0.76431
POMC proopiomelanocortin 0.748017
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.743547
MAOA monoamine oxidase A 0.729357
CES1P1 carboxylesterase 1 pseudogene 1 0.719654
LHB luteinizing hormone beta polypeptide 0.717635
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.702732
TRH thyrotropin-releasing hormone 0.683493
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 0.665166
TTR transthyretin 0.661197
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.658422
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.654858
MED29 mediator complex subunit 29 0.647348
EGF epidermal growth factor 0.637889
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.623751
IPP intracisternal A particle-promoted polypeptide 0.623359
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.621008
CAPS2 calcyphosine 2 0.604981
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.60186
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.581217
VIP vasoactive intestinal peptide 0.580439
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 0.579272
PPAN peter pan homolog (Drosophila) 0.57655
LY96 lymphocyte antigen 96 0.569941
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.56722
ZNF135 zinc finger protein 135 0.538506
MC3R melanocortin 3 receptor 0.528449
IGF1 insulin-like growth factor 1 (somatomedin C) 0.51534
TF transferrin 0.513417
PDLIM2 PDZ and LIM domain 2 (mystique) 0.491978
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.490072
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.487407
NPS neuropeptide S 0.479047
ESR1 estrogen receptor 1 0.478668
PTH parathyroid hormone 0.476014
CLCF1 cardiotrophin-like cytokine factor 1 0.474877
PNP purine nucleoside phosphorylase 0.469576
ACPT acid phosphatase, testicular 0.463527
C6ORF25 chromosome 6 open reading frame 25 0.443923
CFD complement factor D (adipsin) 0.442418
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.442418
TBX3 T-box 3 0.441666
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.436402
GRHL1 grainyhead-like 1 (Drosophila) 0.436026
UROS uroporphyrinogen III synthase 0.42814
AASS aminoadipate-semialdehyde synthase 0.427765
NPY neuropeptide Y 0.413901
DRD2 dopamine receptor D2 0.401199
IFNLR1 interferon, lambda receptor 1 0.391513
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.386679
MC5R melanocortin 5 receptor 0.384822
PTDSS1 phosphatidylserine synthase 1 0.373328
NOVA2 neuro-oncological ventral antigen 2 0.371477
CLMP CXADR-like membrane protein 0.370737
HDAC10 histone deacetylase 10 0.367779
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.365932
HRH1 histamine receptor H1 0.365932
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.365193
AKTIP AKT interacting protein 0.364085
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.362609
FTH1 ferritin, heavy polypeptide 1 0.361502
FTL ferritin, light polypeptide 0.357814
PARP14 poly (ADP-ribose) polymerase family, member 14 0.357077
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.357077
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.355235
NPR1 natriuretic peptide receptor 1 0.355235
NLE1 notchless homolog 1 (Drosophila) 0.355235
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.354499
GUCY2C guanylate cyclase 2C 0.354499
SIRPA signal-regulatory protein alpha 0.352291
STPG1 sperm-tail PG-rich repeat containing 1 0.344574
KLF11 Kruppel-like factor 11 0.343106
CRH corticotropin releasing hormone 0.342739
MPST mercaptopyruvate sulfurtransferase 0.339073
ALB albumin 0.325552
ARR3 arrestin 3, retinal (X-arrestin) 0.324458
STAR steroidogenic acute regulatory protein 0.324458
CD4 CD4 molecule 0.324094
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.319726
MVD mevalonate (diphospho) decarboxylase 0.318999
KRT75 keratin 75, type II 0.312102
USH1G Usher syndrome 1G (autosomal recessive) 0.309566
BDNF brain-derived neurotrophic factor 0.300894
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.290103
GRP gastrin-releasing peptide 0.285086
NOS1 nitric oxide synthase 1 (neuronal) 0.277227
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.275089
HFE2 hemochromatosis type 2 (juvenile) 0.27153
LACTB lactamase, beta 0.271174
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.270108
PDE11A phosphodiesterase 11A 0.264431
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.26266
GHRH growth hormone releasing hormone 0.262306
SEPT3 septin 3 0.261952
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 0.257005
LIF leukemia inhibitory factor 0.252774
CD1A CD1a molecule 0.251718
TFR2 transferrin receptor 2 0.246098
FLNA filamin A, alpha 0.242945
KIAA0101 KIAA0101 0.237706
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.235964
GRIK4 glutamate receptor, ionotropic, kainate 4 0.233183
ICT1 immature colon carcinoma transcript 1 0.227642
REN renin 0.225917
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.225229
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.223853
EDN1 endothelin 1 0.217352
GHRL ghrelin/obestatin prepropeptide 0.215992
OPN3 opsin 3 0.206913
DKKL1 dickkopf-like 1 0.201962
ADRA1A adrenoceptor alpha 1A 0.199681
HAS1 hyaluronan synthase 1 0.194548
SMTNL1 smoothelin-like 1 0.192971
SHF Src homology 2 domain containing F 0.192344
B3GAT2 beta-1,3-glucuronyltransferase 2 0.190786
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.188632
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.188326
HEXB hexosaminidase B (beta polypeptide) 0.188326
SOX3 SRY (sex determining region Y)-box 3 0.18472
SMTN smoothelin 0.184128
SST somatostatin 0.182666
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.17896
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.176485
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.176215
EGR3 early growth response 3 0.176215
EZR ezrin 0.174093
DCXR dicarbonyl/L-xylulose reductase 0.172038
TGFB1 transforming growth factor, beta 1 0.167915
INA internexin neuronal intermediate filament protein, alpha 0.164219
RORA RAR-related orphan receptor A 0.163729
POLK polymerase (DNA directed) kappa 0.163111
ZDHHC23 zinc finger, DHHC-type containing 23 0.162908
TGFB3 transforming growth factor, beta 3 0.158605
ACPP acid phosphatase, prostate 0.158605
PDE4A phosphodiesterase 4A, cAMP-specific 0.14765
CAV1 caveolin 1, caveolae protein, 22kDa 0.144579
RNASE3 ribonuclease, RNase A family, 3 0.143884
ADA adenosine deaminase 0.14351
HAMP hepcidin antimicrobial peptide 0.139753
FMR1 fragile X mental retardation 1 0.139712
CLNK cytokine-dependent hematopoietic cell linker 0.13964
SHH sonic hedgehog 0.139284
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.139217
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.139115
RBMS1 RNA binding motif, single stranded interacting protein 1 0.138846
ECI1 enoyl-CoA delta isomerase 1 0.138846
IGLL5 immunoglobulin lambda-like polypeptide 5 0.138797
FBLIM1 filamin binding LIM protein 1 0.138321
CSN3 casein kappa 0.137835
RPIA ribose 5-phosphate isomerase A 0.137563
TFG TRK-fused gene 0.136099
SARS seryl-tRNA synthetase 0.136045
LATS2 large tumor suppressor kinase 2 0.135605
SRR serine racemase 0.135433
SACS sacsin molecular chaperone 0.135414
GP2 glycoprotein 2 (zymogen granule membrane) 0.135098
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.135018
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.134623
TGFB2 transforming growth factor, beta 2 0.134299