sertoli cell-only syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_0050457)
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Genes

137 genes co-occuring with the disease sertoli cell-only syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
DAZ2 deleted in azoospermia 2 1.87423
LRWD1 leucine-rich repeats and WD repeat domain containing 1 1.78804
DAZ1 deleted in azoospermia 1 1.72092
RNFT1 ring finger protein, transmembrane 1 1.53789
DNAAF3 dynein, axonemal, assembly factor 3 1.53789
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 1.50052
TMEM95 transmembrane protein 95 1.50052
USP26 ubiquitin specific peptidase 26 1.45045
HSFY1 heat shock transcription factor, Y-linked 1 1.42104
HSFY2 heat shock transcription factor, Y linked 2 1.42104
SEPT12 septin 12 1.41709
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 1.39083
TM9SF2 transmembrane 9 superfamily member 2 1.38341
ZNF253 zinc finger protein 253 1.30576
SPATA22 spermatogenesis associated 22 1.30576
LSM12 LSM12 homolog (S. cerevisiae) 1.28566
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 1.24211
SPATA16 spermatogenesis associated 16 1.24168
SPATA12 spermatogenesis associated 12 1.22995
PRM2 protamine 2 1.22562
TDRD3 tudor domain containing 3 1.21175
SPATA17 spermatogenesis associated 17 1.20656
GAS8 growth arrest-specific 8 1.18712
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.17808
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 1.16392
SYCP1 synaptonemal complex protein 1 1.15496
USP9Y ubiquitin specific peptidase 9, Y-linked 1.15325
DAZL deleted in azoospermia-like 1.15283
RBMXL2 RNA binding motif protein, X-linked-like 2 1.1524
CECR2 cat eye syndrome chromosome region, candidate 2 1.13078
ETV5 ets variant 5 1.10931
FSHR follicle stimulating hormone receptor 1.0071
TEX101 testis expressed 101 0.987271
CCNA1 cyclin A1 0.967083
STAG3 stromal antigen 3 0.963309
SERBP1 SERPINE1 mRNA binding protein 1 0.947435
PROX2 prospero homeobox 2 0.928346
GDF6 growth differentiation factor 6 0.921736
KIF18A kinesin family member 18A 0.904442
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.902799
TDRD1 tudor domain containing 1 0.892129
OSCP1 organic solute carrier partner 1 0.879014
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.840934
CDY1 chromodomain protein, Y-linked, 1 0.800333
AVEN apoptosis, caspase activation inhibitor 0.781479
AKAP4 A kinase (PRKA) anchor protein 4 0.781069
SPO11 SPO11 meiotic protein covalently bound to DSB 0.77575
INHA inhibin, alpha 0.772887
NXF2 nuclear RNA export factor 2 0.762678
NXF2B nuclear RNA export factor 2B 0.762678
ING2 inhibitor of growth family, member 2 0.742735
TERT telomerase reverse transcriptase 0.740299
FOXA3 forkhead box A3 0.739894
GGPS1 geranylgeranyl diphosphate synthase 1 0.738676
MSH4 mutS homolog 4 0.728143
STRA8 stimulated by retinoic acid 8 0.727333
ZNF384 zinc finger protein 384 0.716828
ARRB2 arrestin, beta 2 0.709572
GJA1 gap junction protein, alpha 1, 43kDa 0.705547
ESX1 ESX homeobox 1 0.70233
HSPA2 heat shock 70kDa protein 2 0.689492
PIWIL2 piwi-like RNA-mediated gene silencing 2 0.683493
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.682294
AMH anti-Mullerian hormone 0.681894
CDY1B chromodomain protein, Y-linked, 1B 0.680697
SYCP3 synaptonemal complex protein 3 0.666755
GNRH2 gonadotropin-releasing hormone 2 0.643009
HIST1H1B histone cluster 1, H1b 0.635135
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.627672
SRY sex determining region Y 0.619051
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.604201
CENPE centromere protein E, 312kDa 0.590169
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.587833
MSH5 mutS homolog 5 0.575383
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.564112
RBM15 RNA binding motif protein 15 0.55945
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.542767
PRM1 protamine 1 0.542379
AMHR2 anti-Mullerian hormone receptor, type II 0.537344
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.534248
DKKL1 dickkopf-like 1 0.524974
FSHB follicle stimulating hormone, beta polypeptide 0.524588
MLH3 mutL homolog 3 0.51842
NUPR1 nuclear protein, transcriptional regulator, 1 0.508041
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.491597
TSPY1 testis specific protein, Y-linked 1 0.483985
GGN gametogenetin 0.479807
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.474498
LHB luteinizing hormone beta polypeptide 0.469954
SET SET nuclear proto-oncogene 0.463905
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.463149
AR androgen receptor 0.447311
TSPY3 testis specific protein, Y-linked 3 0.438658
TSPY10 testis specific protein, Y-linked 10 0.438658
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.438282
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.434524
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.42214
NDRG2 NDRG family member 2 0.418019
TDRD6 tudor domain containing 6 0.413527
FGF9 fibroblast growth factor 9 0.412031
ECM1 extracellular matrix protein 1 0.410909
DDR1 discoidin domain receptor tyrosine kinase 1 0.400453
CLDN11 claudin 11 0.397098
ESR2 estrogen receptor 2 (ER beta) 0.371477
SORD sorbitol dehydrogenase 0.363716
MRI1 methylthioribose-1-phosphate isomerase 1 0.362609
SHBG sex hormone-binding globulin 0.362239
INSL3 insulin-like 3 (Leydig cell) 0.352291
SEPT5 septin 5 0.346777
RHOB ras homolog family member B 0.342739
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.32993
MGAT4C MGAT4 family, member C 0.312102
KRT10 keratin 10, type I 0.301254
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.286519
IFT122 intraflagellar transport 122 0.272953
GNRHR gonadotropin-releasing hormone receptor 0.270464
IL1R1 interleukin 1 receptor, type I 0.264785
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.263014
GPER1 G protein-coupled estrogen receptor 1 0.259477
FOXA1 forkhead box A1 0.256299
HMBS hydroxymethylbilane synthase 0.255594
BIRC5 baculoviral IAP repeat containing 5 0.245396
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.244696
PGM1 phosphoglucomutase 1 0.228679
PRDX1 peroxiredoxin 1 0.227988
PHB prohibitin 0.227297
CARD17 caspase recruitment domain family, member 17 0.218034
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.204593
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.203933
RAD50 RAD50 homolog (S. cerevisiae) 0.198386
FBXO32 F-box protein 32 0.190476
GATA2 GATA binding protein 2 0.189551
CDC25A cell division cycle 25A 0.182957
CCNE1 cyclin E1 0.177301
CREM cAMP responsive element modulator 0.161523
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.160948
STS steroid sulfatase (microsomal), isozyme S 0.158778