sertaconazole-6811 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sertaconazole-6811 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
AIM1L absent in melanoma 1-like
APOL6 apolipoprotein L, 6
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
ATP9A ATPase, class II, type 9A
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDKRB2 bradykinin receptor B2
CALD1 caldesmon 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD47 CD47 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CLCN1 chloride channel, voltage-sensitive 1
CTSZ cathepsin Z
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DCAF4 DDB1 and CUL4 associated factor 4
DIO2 deiodinase, iodothyronine, type II
DLK2 delta-like 2 homolog (Drosophila)
DNASE1 deoxyribonuclease I
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSC3 desmocollin 3
DTX3 deltex 3, E3 ubiquitin ligase
EFCAB6 EF-hand calcium binding domain 6
ELF5 E74-like factor 5 (ets domain transcription factor)
EPHB2 EPH receptor B2
FAM155A family with sequence similarity 155, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGF2 fibroblast growth factor 2 (basic)
FOXP3 forkhead box P3
GLIPR1 GLI pathogenesis-related 1
GPR176 G protein-coupled receptor 176
GRK5 G protein-coupled receptor kinase 5
HDAC5 histone deacetylase 5
HNF1B HNF1 homeobox B
HNMT histamine N-methyltransferase
HOXA6 homeobox A6
HSPG2 heparan sulfate proteoglycan 2
IFNA10 interferon, alpha 10
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
KIAA0125 KIAA0125
KIAA1109 KIAA1109
KLHL24 kelch-like family member 24
LGALS9 lectin, galactoside-binding, soluble, 9
LTB lymphotoxin beta (TNF superfamily, member 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAOB monoamine oxidase B
MEF2D myocyte enhancer factor 2D
MMP25 matrix metallopeptidase 25
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NPPA natriuretic peptide A
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
ONECUT2 one cut homeobox 2
PCDH11Y protocadherin 11 Y-linked
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POPDC3 popeye domain containing 3
POU3F2 POU class 3 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PQLC2 PQ loop repeat containing 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RIMS3 regulating synaptic membrane exocytosis 3
RIN3 Ras and Rab interactor 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF43 ring finger protein 43
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
SCAPER S-phase cyclin A-associated protein in the ER
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SH3GL3 SH3-domain GRB2-like 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPRR1B small proline-rich protein 1B
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAS2R10 taste receptor, type 2, member 10
TBKBP1 TBK1 binding protein 1
TCP11L1 t-complex 11, testis-specific-like 1
TFPI2 tissue factor pathway inhibitor 2
TGFB2 transforming growth factor, beta 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRDMT1 tRNA aspartic acid methyltransferase 1
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA4B tubulin, alpha 4b
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDR33 WD repeat domain 33
XYLB xylulokinase homolog (H. influenzae)
ZNF532 zinc finger protein 532
ZNF710 zinc finger protein 710
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAP2 ArfGAP with dual PH domains 2
ADRA2C adrenoceptor alpha 2C
ANP32A-IT1 ANP32A intronic transcript 1
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF105 chromosome 1 open reading frame 105
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAPG capping protein (actin filament), gelsolin-like
CARD8 caspase recruitment domain family, member 8
CCNO cyclin O
CENPO centromere protein O
CHM choroideremia (Rab escort protein 1)
CHMP7 charged multivesicular body protein 7
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLEC16A C-type lectin domain family 16, member A
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DENND5A DENN/MADD domain containing 5A
DGAT1 diacylglycerol O-acyltransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP2 dual specificity phosphatase 2
DYSF dysferlin
ECHDC2 enoyl CoA hydratase domain containing 2
FAM46C family with sequence similarity 46, member C
FAN1 FANCD2/FANCI-associated nuclease 1
FBXO31 F-box protein 31
FHOD1 formin homology 2 domain containing 1
FOXI1 forkhead box I1
GAMT guanidinoacetate N-methyltransferase
GMIP GEM interacting protein
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTA4 glutathione S-transferase alpha 4
HDAC7 histone deacetylase 7
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
KLC2 kinesin light chain 2
LHX6 LIM homeobox 6
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MFAP2 microfibrillar-associated protein 2
MNX1 motor neuron and pancreas homeobox 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NEK11 NIMA-related kinase 11
NFE2L3 nuclear factor, erythroid 2-like 3
NPFFR1 neuropeptide FF receptor 1
NPY5R neuropeptide Y receptor Y5
PADI1 peptidyl arginine deiminase, type I
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PP14571 uncharacterized LOC100130449
PRODH proline dehydrogenase (oxidase) 1
RAB3A RAB3A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RIN2 Ras and Rab interactor 2
RRAGB Ras-related GTP binding B
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
TAOK1 TAO kinase 1
TBX19 T-box 19
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TNK1 tyrosine kinase, non-receptor, 1
TRAPPC2 trafficking protein particle complex 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBG2 tubulin, gamma 2
VASH1 vasohibin 1
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
ZNF219 zinc finger protein 219
ZNF282 zinc finger protein 282
ZNF408 zinc finger protein 408
ZNF492 zinc finger protein 492
ZNF516 zinc finger protein 516
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747