sertaconazole-4475 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sertaconazole-4475 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADD2 adducin 2 (beta)
ANP32A-IT1 ANP32A intronic transcript 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
C1ORF61 chromosome 1 open reading frame 61
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC170 coiled-coil domain containing 170
CCDC71 coiled-coil domain containing 71
CD4 CD4 molecule
CD68 CD68 molecule
CELF2 CUGBP, Elav-like family member 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL5A1 collagen, type V, alpha 1
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CUZD1 CUB and zona pellucida-like domains 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLC1 DLC1 Rho GTPase activating protein
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOCK9 dedicator of cytokinesis 9
DRD2 dopamine receptor D2
DSCR4 Down syndrome critical region 4
DTNA dystrobrevin, alpha
DYM dymeclin
ELSPBP1 epididymal sperm binding protein 1
EPN1 epsin 1
ESR1 estrogen receptor 1
FBXO31 F-box protein 31
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FOXO4 forkhead box O4
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIK5 glutamate receptor, ionotropic, kainate 5
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HESX1 HESX homeobox 1
HEXA hexosaminidase A (alpha polypeptide)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KITLG KIT ligand
KMT2A lysine (K)-specific methyltransferase 2A
LIMK2 LIM domain kinase 2
LTBP4 latent transforming growth factor beta binding protein 4
MAL mal, T-cell differentiation protein
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MFGE8 milk fat globule-EGF factor 8 protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLANA melan-A
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NCOR2 nuclear receptor corepressor 2
NELL2 NEL-like 2 (chicken)
NFASC neurofascin
NOX1 NADPH oxidase 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIPOX pipecolic acid oxidase
PLA2G5 phospholipase A2, group V
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDM12 PR domain containing 12
PRR5 proline rich 5 (renal)
PTCRA pre T-cell antigen receptor alpha
PTGDR2 prostaglandin D2 receptor 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRU protein tyrosine phosphatase, receptor type, U
RIF1 replication timing regulatory factor 1
RIMS3 regulating synaptic membrane exocytosis 3
RLN1 relaxin 1
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC16A6 solute carrier family 16, member 6
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SORBS1 sorbin and SH3 domain containing 1
SPRR1A small proline-rich protein 1A
TAPBPL TAP binding protein-like
TCP10 t-complex 10
TMPRSS2 transmembrane protease, serine 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOP3B topoisomerase (DNA) III beta
TTC38 tetratricopeptide repeat domain 38
TUBA4B tubulin, alpha 4b
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTS2 urotensin 2
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VIPR2 vasoactive intestinal peptide receptor 2
WDR78 WD repeat domain 78
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADGRG2 adhesion G protein-coupled receptor G2
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AZI2 5-azacytidine induced 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1ORF105 chromosome 1 open reading frame 105
C5ORF45 chromosome 5 open reading frame 45
CCDC9 coiled-coil domain containing 9
CCNJL cyclin J-like
CCNO cyclin O
CLIC3 chloride intracellular channel 3
CLK1 CDC-like kinase 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE7 copine VII
CRY2 cryptochrome circadian clock 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND5B DENN/MADD domain containing 5B
E2F8 E2F transcription factor 8
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ESM1 endothelial cell-specific molecule 1
FAIM Fas apoptotic inhibitory molecule
FANCF Fanconi anemia, complementation group F
FBP1 fructose-1,6-bisphosphatase 1
FBRS fibrosin
FBXL4 F-box and leucine-rich repeat protein 4
FBXO5 F-box protein 5
FPGS folylpolyglutamate synthase
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GCA grancalcin, EF-hand calcium binding protein
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HIST1H4C histone cluster 1, H4c
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT81 intraflagellar transport 81
IL17RB interleukin 17 receptor B
IL33 interleukin 33
IPP intracisternal A particle-promoted polypeptide
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ISYNA1 inositol-3-phosphate synthase 1
KDM4D lysine (K)-specific demethylase 4D
KDM7A lysine (K)-specific demethylase 7A
KIAA0513 KIAA0513
LMNB1 lamin B1
MANSC1 MANSC domain containing 1
MBIP MAP3K12 binding inhibitory protein 1
MDFI MyoD family inhibitor
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL44 mitochondrial ribosomal protein L44
MUC3A mucin 3A, cell surface associated
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NME5 NME/NM23 family member 5
NT5DC3 5'-nucleotidase domain containing 3
OSR2 odd-skipped related transciption factor 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAQR6 progestin and adipoQ receptor family member VI
PER3 period circadian clock 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS19 regulator of G-protein signaling 19
RPAIN RPA interacting protein
RUNX1-IT1 RUNX1 intronic transcript 1
SDC3 syndecan 3
SNHG20 small nucleolar RNA host gene 20
SNX16 sorting nexin 16
SPATA7 spermatogenesis associated 7
SRBD1 S1 RNA binding domain 1
SYT17 synaptotagmin XVII
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TH tyrosine hydroxylase
TMC7 transmembrane channel-like 7
TMEM254 transmembrane protein 254
TMEM260 transmembrane protein 260
TMEM53 transmembrane protein 53
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRDMT1 tRNA aspartic acid methyltransferase 1
USB1 U6 snRNA biogenesis 1
ZNF358 zinc finger protein 358
ZNF573 zinc finger protein 573
ZNF76 zinc finger protein 76
ZNF770 zinc finger protein 770
ZSCAN31 zinc finger and SCAN domain containing 31