serotonin-3311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the serotonin-3311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAM22 ADAM metallopeptidase domain 22
AGFG2 ArfGAP with FG repeats 2
ALMS1 Alstrom syndrome protein 1
APOE apolipoprotein E
ARC activity-regulated cytoskeleton-associated protein
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASB1 ankyrin repeat and SOCS box containing 1
ATM ATM serine/threonine kinase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BBS9 Bardet-Biedl syndrome 9
CA5B carbonic anhydrase VB, mitochondrial
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL19 chemokine (C-C motif) ligand 19
CFLAR CASP8 and FADD-like apoptosis regulator
CNOT4 CCR4-NOT transcription complex, subunit 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYTH4 cytohesin 4
DNAAF1 dynein, axonemal, assembly factor 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELSPBP1 epididymal sperm binding protein 1
ETV5 ets variant 5
FAM212B family with sequence similarity 212, member B
FANCA Fanconi anemia, complementation group A
FGF22 fibroblast growth factor 22
FN1 fibronectin 1
FOXN3 forkhead box N3
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOLGA8A golgin A8 family, member A
GPC1 glypican 1
GRIP2 glutamate receptor interacting protein 2
GRM8 glutamate receptor, metabotropic 8
GUSBP3 glucuronidase, beta pseudogene 3
HPSE2 heparanase 2 (inactive)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IL17RC interleukin 17 receptor C
IL6ST interleukin 6 signal transducer
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LATS1 large tumor suppressor kinase 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LSP1 lymphocyte-specific protein 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MRPS12 mitochondrial ribosomal protein S12
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRF1L mitochondrial translational release factor 1-like
NEK1 NIMA-related kinase 1
NPR1 natriuretic peptide receptor 1
NT5M 5',3'-nucleotidase, mitochondrial
ONECUT2 one cut homeobox 2
PCDHA5 protocadherin alpha 5
PILRA paired immunoglobin-like type 2 receptor alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX1 paired-like homeodomain 1
PNRC1 proline-rich nuclear receptor coactivator 1
PRKCE protein kinase C, epsilon
PTCRA pre T-cell antigen receptor alpha
RAB3B RAB3B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBFA ribosome binding factor A (putative)
RBM5 RNA binding motif protein 5
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS14 regulator of G-protein signaling 14
RNFT1 ring finger protein, transmembrane 1
SIRT4 sirtuin 4
SKI SKI proto-oncogene
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A17 solute carrier family 22, member 17
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SPON1 spondin 1, extracellular matrix protein
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRP72 signal recognition particle 72kDa
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
SULT4A1 sulfotransferase family 4A, member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM63A transmembrane protein 63A
TPP1 tripeptidyl peptidase I
TUBBP5 tubulin, beta pseudogene 5
UGT8 UDP glycosyltransferase 8
UPK2 uroplakin 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF34 zinc finger protein 34
ZNF589 zinc finger protein 589
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTL8 actin-like 8
ADM adrenomedullin
ALS2CL ALS2 C-terminal like
ASAP1-IT1 ASAP1 intronic transcript 1
C11ORF80 chromosome 11 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX4 chromobox homolog 4
CBX7 chromobox homolog 7
CDK3 cyclin-dependent kinase 3
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTC1 CTS telomere maintenance complex component 1
DCP1A decapping mRNA 1A
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM169A family with sequence similarity 169, member A
FHOD1 formin homology 2 domain containing 1
FLCN folliculin
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXN2 forkhead box N2
FRK fyn-related Src family tyrosine kinase
FURIN furin (paired basic amino acid cleaving enzyme)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR143 G protein-coupled receptor 143
HIST1H2AE histone cluster 1, H2ae
HLA-DMA major histocompatibility complex, class II, DM alpha
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IRF7 interferon regulatory factor 7
ITPKB inositol-trisphosphate 3-kinase B
KDM7A lysine (K)-specific demethylase 7A
KREMEN2 kringle containing transmembrane protein 2
LARP6 La ribonucleoprotein domain family, member 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LY6D lymphocyte antigen 6 complex, locus D
MAST3 microtubule associated serine/threonine kinase 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP62CL nucleoporin 62kDa C-terminal like
NUPL2 nucleoporin like 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARPBP PARP1 binding protein
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER3 period circadian clock 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMEL premelanosome protein
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
RIN2 Ras and Rab interactor 2
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIDT1 SID1 transmembrane family, member 1
SIRT6 sirtuin 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SP1 Sp1 transcription factor
STARD3 StAR-related lipid transfer (START) domain containing 3
STX5 syntaxin 5
SYCP2 synaptonemal complex protein 2
TCTA T-cell leukemia translocation altered
TESC tescalcin
THBS3 thrombospondin 3
TM6SF1 transmembrane 6 superfamily member 1
TMC7 transmembrane channel-like 7
TMEM120B transmembrane protein 120B
TMEM184C transmembrane protein 184C
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TMEM57 transmembrane protein 57
TMSB15A thymosin beta 15a
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTC4 tetratricopeptide repeat domain 4
VGF VGF nerve growth factor inducible
WDR91 WD repeat domain 91
ZBTB6 zinc finger and BTB domain containing 6
ZNF134 zinc finger protein 134
ZNF492 zinc finger protein 492
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747