serine-type endopeptidase inhibitor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme. (Gene Ontology, GO_0004867)
External Link http://amigo.geneontology.org/amigo/term/GO:0004867
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Genes

88 genes performing the serine-type endopeptidase inhibitor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AMBP alpha-1-microglobulin/bikunin precursor
ANOS1 anosmin 1
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
CD109 CD109 molecule
COL28A1 collagen, type XXVIII, alpha 1
COL6A3 collagen, type VI, alpha 3
COL7A1 collagen, type VII, alpha 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
FURIN furin (paired basic amino acid cleaving enzyme)
HMSD histocompatibility (minor) serpin domain containing
HRG histidine-rich glycoprotein
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PEBP1 phosphatidylethanolamine binding protein 1
PI3 peptidase inhibitor 3, skin-derived
RECK reversion-inducing-cysteine-rich protein with kazal motifs
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPINK9 serine peptidase inhibitor, Kazal type 9
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SPINT4 serine peptidase inhibitor, Kunitz type 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
WFDC1 WAP four-disulfide core domain 1
WFDC10A WAP four-disulfide core domain 10A
WFDC12 WAP four-disulfide core domain 12
WFDC13 WAP four-disulfide core domain 13
WFDC2 WAP four-disulfide core domain 2
WFDC3 WAP four-disulfide core domain 3
WFDC5 WAP four-disulfide core domain 5
WFDC8 WAP four-disulfide core domain 8
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2