sepsis; systemic infection Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group infection (Genetic Association Database)
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Genes

28 genes associated with the disease sepsis; systemic infection in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
APOE apolipoprotein E
BPI bactericidal/permeability-increasing protein
CD14 CD14 molecule
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
F5 coagulation factor V (proaccelerin, labile factor)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4R interleukin 4 receptor
IL6 interleukin 6
IRAK1 interleukin-1 receptor-associated kinase 1
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MYD88 myeloid differentiation primary response 88
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNF tumor necrosis factor