sensory system disease Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell). (Human Disease Ontology, DOID_0050155)
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Genes

247 genes associated with the disease sensory system disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HTRA1 HtrA serine peptidase 1 3.31608
CFH complement factor H 3.31608
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 2.50425
LOXL1 lysyl oxidase-like 1 1.67092
CDH8 cadherin 8, type 2 1.62569
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.60583
SAMD5 sterile alpha motif domain containing 5 1.51016
CFB complement factor B 1.51016
KNG1 kininogen 1 1.41921
APOC1 apolipoprotein C-I 1.37597
LRRK1 leucine-rich repeat kinase 1 1.30085
TCF4 transcription factor 4 1.2894
CADM2 cell adhesion molecule 2 1.27521
KLF5 Kruppel-like factor 5 (intestinal) 1.2206
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.17894
MIPEP mitochondrial intermediate peptidase 1.14929
ASPA aspartoacylase 1.12703
C3ORF58 chromosome 3 open reading frame 58 1.09588
ANXA6 annexin A6 1.09588
KIAA0825 KIAA0825 1.06123
ZNF285 zinc finger protein 285 1.06123
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.05198
MTAP methylthioadenosine phosphorylase 1.05198
NAV3 neuron navigator 3 1.05198
FOXO1 forkhead box O1 0.987984
TPT1 tumor protein, translationally-controlled 1 0.945428
BICC1 BicC family RNA binding protein 1 0.945428
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.923046
COL8A1 collagen, type VIII, alpha 1 0.923046
C4ORF32 chromosome 4 open reading frame 32 0.901326
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.894262
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.894262
LAMA2 laminin, alpha 2 0.872896
ZNF536 zinc finger protein 536 0.85991
CARD10 caspase recruitment domain family, member 10 0.85991
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.850113
LPAR1 lysophosphatidic acid receptor 1 0.842276
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.842276
FNDC3B fibronectin type III domain containing 3B 0.842276
COL5A1 collagen, type V, alpha 1 0.842276
PRR31 proline rich 31 0.835734
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.817078
CAV1 caveolin 1, caveolae protein, 22kDa 0.790827
IER3 immediate early response 3 0.790827
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.790827
DENND1A DENN/MADD domain containing 1A 0.790827
NOTCH4 notch 4 0.790827
LIPC lipase, hepatic 0.774217
TGFBR1 transforming growth factor, beta receptor 1 0.774217
TJP1 tight junction protein 1 0.774217
COL8A2 collagen, type VIII, alpha 2 0.774217
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.7623
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.752991
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.752991
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.745324
SHISA6 shisa family member 6 0.738873
CCDC109B coiled-coil domain containing 109B 0.738873
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.73332
SCML4 sex comb on midleg-like 4 (Drosophila) 0.73332
RAD51B RAD51 paralog B 0.728541
MYO1D myosin ID 0.724323
PBLD phenazine biosynthesis-like protein domain containing 0.69843
GLT8D2 glycosyltransferase 8 domain containing 2 0.69843
NELFE negative elongation factor complex member E 0.69843
TMEM248 transmembrane protein 248 0.682635
ADCY2 adenylate cyclase 2 (brain) 0.682635
ATOH7 atonal homolog 7 (Drosophila) 0.682635
ZMAT4 zinc finger, matrin-type 4 0.670996
CFI complement factor I 0.670996
SMAD3 SMAD family member 3 0.661797
ARID5B AT rich interactive domain 5B (MRF1-like) 0.65413
COL11A1 collagen, type XI, alpha 1 0.63666
ZFPM2 zinc finger protein, FOG family member 2 0.63666
MAP3K19 mitogen-activated protein kinase kinase kinase 19 0.63207
TNXB tenascin XB 0.63207
LPPR5 lipid phosphate phosphatase-related protein type 5 0.63207
ZNF692 zinc finger protein 692 0.63207
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.63207
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.63207
ATF6B activating transcription factor 6 beta 0.63207
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.602429
CHSY1 chondroitin sulfate synthase 1 0.602429
ARHGAP22 Rho GTPase activating protein 22 0.602429
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.58494
SRBD1 S1 RNA binding domain 1 0.58494
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 0.572184
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.572184
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.561725
PTPRR protein tyrosine phosphatase, receptor type, R 0.561725
HABP2 hyaluronan binding protein 2 0.561725
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.552621
TJP2 tight junction protein 2 0.544585
CETP cholesteryl ester transfer protein, plasma 0.544585
RNF135 ring finger protein 135 0.537125
VEGFA vascular endothelial growth factor A 0.5306
PLXDC2 plexin domain containing 2 0.5306
CHEK2 checkpoint kinase 2 0.52461
C3 complement component 3 0.52461
GAS7 growth arrest-specific 7 0.52461
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.52461
C14ORF39 chromosome 14 open reading frame 39 0.52461
GK2 glycerol kinase 2 0.52461
DCLK1 doublecortin-like kinase 1 0.52461
FRK fyn-related Src family tyrosine kinase 0.52461
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.486425
B3GALTL beta 1,3-galactosyltransferase-like 0.486425
COL10A1 collagen, type X, alpha 1 0.486425
BMP2 bone morphogenetic protein 2 0.486425
REST RE1-silencing transcription factor 0.486425
RELN reelin 0.486425
NT5DC1 5'-nucleotidase domain containing 1 0.486425
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.486425
PCCA propionyl CoA carboxylase, alpha polypeptide 0.486425
TMCO1 transmembrane and coiled-coil domains 1 0.486425
BCAS3 breast carcinoma amplified sequence 3 0.464771
SFRP4 secreted frizzled-related protein 4 0.449873
RORB RAR-related orphan receptor B 0.449873
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.449873
PML promyelocytic leukemia 0.438544
RERE arginine-glutamic acid dipeptide (RE) repeats 0.429338
ZWINT ZW10 interacting kinetochore protein 0.408752
PDE7A phosphodiesterase 7A 0.403461
ZBTB18 zinc finger and BTB domain containing 18 0.403461
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.368757
TXNRD2 thioredoxin reductase 2 0.368757
TACC2 transforming, acidic coiled-coil containing protein 2 0.368757
RFTN1 raftlin, lipid raft linker 1 0.368757
SRPK2 SRSF protein kinase 2 0.368757
VAX2 ventral anterior homeobox 2 0.368757
OR5M3 olfactory receptor, family 5, subfamily M, member 3 0.368757
MYPN myopalladin 0.368757
PLA2G12A phospholipase A2, group XIIA 0.345945
SOD2 superoxide dismutase 2, mitochondrial 0.345945
TGFBR3 transforming growth factor, beta receptor III 0.345945
LRP1B low density lipoprotein receptor-related protein 1B 0.345945
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.345945
MYSM1 Myb-like, SWIRM and MPN domains 1 0.345945
SPTBN1 spectrin, beta, non-erythrocytic 1 0.345945
BMP6 bone morphogenetic protein 6 0.327313
USP11 ubiquitin specific peptidase 11 0.327313
IQGAP2 IQ motif containing GTPase activating protein 2 0.327313
FSTL5 follistatin-like 5 0.327313
NCKAP5 NCK-associated protein 5 0.327313
CLSTN2 calsyntenin 2 0.327313
MBP myelin basic protein 0.327313
CA8 carbonic anhydrase VIII 0.327313
MCHR2 melanin-concentrating hormone receptor 2 0.311576
STOML1 stomatin (EPB72)-like 1 0.311576
LPP LIM domain containing preferred translocation partner in lipoma 0.311576
SATB2 SATB homeobox 2 0.297866
PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.297866
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.297866
CCNL1 cyclin L1 0.285417
PTPRD protein tyrosine phosphatase, receptor type, D 0.264872
VEPH1 ventricular zone expressed PH domain-containing 1 0.264872
RREB1 ras responsive element binding protein 1 0.256228
KIAA1551 KIAA1551 0.256228
GCOM1 GRINL1A complex locus 1 0.256228
BMP3 bone morphogenetic protein 3 0.256228
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.256228
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 0.256228
PTPRG protein tyrosine phosphatase, receptor type, G 0.256228
UBXN4 UBX domain protein 4 0.256228
TBC1D21 TBC1 domain family, member 21 0.256228
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.256228
DNAH5 dynein, axonemal, heavy chain 5 0.256228
MBL2 mannose-binding lectin (protein C) 2, soluble 0.197766
AMY1A amylase, alpha 1A (salivary) 0.197766
DLK1 delta-like 1 homolog (Drosophila) 0.197766
PTPRK protein tyrosine phosphatase, receptor type, K 0.197766
CHAF1B chromatin assembly factor 1, subunit B (p60) 0.197766
BHLHE40 basic helix-loop-helix family, member e40 0.197766
MAML2 mastermind-like 2 (Drosophila) 0.197766
TAC1 tachykinin, precursor 1 0.197766
FOXF1 forkhead box F1 0.197766
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.197766
SCFD2 sec1 family domain containing 2 0.197766
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 0.197766
SCPEP1 serine carboxypeptidase 1 0.197766
RPTOR regulatory associated protein of MTOR, complex 1 0.197766
EYS eyes shut homolog (Drosophila) 0.197766
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 0.197766
ERI1 exoribonuclease 1 0.15771
DNAH9 dynein, axonemal, heavy chain 9 0.15771
AP1B1 adaptor-related protein complex 1, beta 1 subunit 0.15771
FHIT fragile histidine triad 0.15771
INSR insulin receptor 0.15771
NUDCD1 NudC domain containing 1 0.15771
UST uronyl-2-sulfotransferase 0.15771
MSRA methionine sulfoxide reductase A 0.15771
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 0.15771
GATA4 GATA binding protein 4 0.126165
OSCP1 organic solute carrier partner 1 0.126165
MFAP3L microfibrillar-associated protein 3-like 0.126165
CNTN5 contactin 5 0.126165
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.126165
MC4R melanocortin 4 receptor 0.126165
PARP8 poly (ADP-ribose) polymerase family, member 8 0.126165
TSHR thyroid stimulating hormone receptor 0.126165
DENND2A DENN/MADD domain containing 2A 0.126165
ELOVL5 ELOVL fatty acid elongase 5 0.126165
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.126165
TYR tyrosinase 0.126165
LMO7 LIM domain 7 0.126165
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.126165
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.126165
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.100789
KLHDC7A kelch domain containing 7A 0.100789
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.100789
POU5F1B POU class 5 homeobox 1B 0.100789
C1ORF132 chromosome 1 open reading frame 132 0.100789
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.100789
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.100789
WIPF3 WAS/WASL interacting protein family, member 3 0.100789
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.080593
NMRK2 nicotinamide riboside kinase 2 0.080593
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.080593
POSTN periostin, osteoblast specific factor 0.080593
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.080593
CHD4 chromodomain helicase DNA binding protein 4 0.080593
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.080593
TNR tenascin R 0.064973
ESRRG estrogen-related receptor gamma 0.064973
MPRIP myosin phosphatase Rho interacting protein 0.064973
PEX14 peroxisomal biogenesis factor 14 0.064973
CREB5 cAMP responsive element binding protein 5 0.064973
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.064973
WDR27 WD repeat domain 27 0.064973
EIF3H eukaryotic translation initiation factor 3, subunit H 0.064973
CAPN9 calpain 9 0.064973
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.064973
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.052255
RAB30 RAB30, member RAS oncogene family 0.052255
SGCZ sarcoglycan, zeta 0.052255
CTNND2 catenin (cadherin-associated protein), delta 2 0.052255
CLIC5 chloride intracellular channel 5 0.052255
THSD7B thrombospondin, type I, domain containing 7B 0.052255
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.052255
NMUR2 neuromedin U receptor 2 0.052255
RUNX1 runt-related transcription factor 1 0.052255
GRAMD3 GRAM domain containing 3 0.043246
GLI3 GLI family zinc finger 3 0.043246
SIX1 SIX homeobox 1 0.043246
MYH9 myosin, heavy chain 9, non-muscle 0.043246
BNC2 basonuclin 2 0.043246
USP53 ubiquitin specific peptidase 53 0.043246
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.043246