sensory peripheral neuropathy Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A peripheral neuropathy that involves damage to nerves of the peripheral nervous system. (Human Disease Ontology, DOID_2491)
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Genes

202 genes co-occuring with the disease sensory peripheral neuropathy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MPZ myelin protein zero 1.53921
MAG myelin associated glycoprotein 1.53789
NGF nerve growth factor (beta polypeptide) 1.46803
PMP22 peripheral myelin protein 22 1.45704
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 1.41665
NTF3 neurotrophin 3 1.35725
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.32541
GJB1 gap junction protein, beta 1, 32kDa 1.30445
TAC1 tachykinin, precursor 1 1.2521
NUMB numb homolog (Drosophila) 1.23212
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 1.19791
MTMR2 myotubularin related protein 2 1.14136
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 1.08034
ATF3 activating transcription factor 3 1.02187
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.0206
DDHD1 DDHD domain containing 1 1.01216
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.999924
C10ORF2 chromosome 10 open reading frame 2 0.99697
DST dystonin 0.9839
FGD4 FYVE, RhoGEF and PH domain containing 4 0.983479
CALCA calcitonin-related polypeptide alpha 0.977165
CST7 cystatin F (leukocystatin) 0.97296
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.965405
POLG polymerase (DNA directed), gamma 0.956196
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.952438
GDAP1 ganglioside induced differentiation associated protein 1 0.950769
WNK1 WNK lysine deficient protein kinase 1 0.941611
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.932484
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.914727
SNN stannin 0.901567
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.893359
ATL3 atlastin GTPase 3 0.889668
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.867549
ATL1 atlastin GTPase 1 0.863046
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.86018
CRIPT cysteine-rich PDZ-binding protein 0.856905
HSPB1 heat shock 27kDa protein 1 0.849126
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.84585
DACH1 dachshund family transcription factor 1 0.836837
RTN2 reticulon 2 0.836017
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 0.833968
RFX2 regulatory factor X, 2 (influences HLA class II expression) 0.832329
HACL1 2-hydroxyacyl-CoA lyase 1 0.831918
SAP30BP SAP30 binding protein 0.827409
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.826178
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 0.817976
TTR transthyretin 0.817155
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.81018
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.806077
XRN1 5'-3' exoribonuclease 1 0.791311
AP4B1 adaptor-related protein complex 4, beta 1 subunit 0.785165
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 0.779841
CD4 CD4 molecule 0.77575
NCAM2 neural cell adhesion molecule 2 0.774523
HSPB3 heat shock 27kDa protein 3 0.770027
PHYH phytanoyl-CoA 2-hydroxylase 0.768393
KIF20B kinesin family member 20B 0.767576
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 0.741923
PRX periaxin 0.740299
KIF1A kinesin family member 1A 0.735433
EPHA5 EPH receptor A5 0.730976
MFN2 mitofusin 2 0.699517
ALB albumin 0.699517
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.696306
AP4M1 adaptor-related protein complex 4, mu 1 subunit 0.681096
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.679499
GAN gigaxonin 0.6791
NPS neuropeptide S 0.677504
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.677105
INS insulin 0.670732
ODF1 outer dense fiber of sperm tails 1 0.667947
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.667152
DDHD2 DDHD domain containing 2 0.657234
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.652089
LITAF lipopolysaccharide-induced TNF factor 0.650903
AMPH amphiphysin 0.64577
FXN frataxin 0.644981
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.642615
IGHMBP2 immunoglobulin mu binding protein 2 0.639463
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.635921
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.632384
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.620617
NTF4 neurotrophin 4 0.614747
SRI sorcin 0.608494
EPHA6 EPH receptor A6 0.606152
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.60147
MFN1 mitofusin 1 0.593285
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.586276
SCN2B sodium channel, voltage gated, type II beta subunit 0.58433
ERVW-1 endogenous retrovirus group W, member 1 0.569941
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.568775
H1F0 H1 histone family, member 0 0.559839
APTX aprataxin 0.55712
SCIN scinderin 0.554015
TNIK TRAF2 and NCK interacting kinase 0.54393
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.533861
KIAA0196 KIAA0196 0.531541
XG Xg blood group 0.521502
DNAH12 dynein, axonemal, heavy chain 12 0.517649
DNAH14 dynein, axonemal, heavy chain 14 0.517649
C12ORF57 chromosome 12 open reading frame 57 0.513417
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.508424
ATXN3 ataxin 3 0.502675
SRPK1 SRSF protein kinase 1 0.498849
RNF25 ring finger protein 25 0.497703
HSPB8 heat shock 22kDa protein 8 0.49274
CNTF ciliary neurotrophic factor 0.489691
TTPA tocopherol (alpha) transfer protein 0.488169
REEP1 receptor accessory protein 1 0.482844
ERBB2 erb-b2 receptor tyrosine kinase 2 0.482464
BCL2L2 BCL2-like 2 0.478668
HSPG2 heparan sulfate proteoglycan 2 0.474877
FAM134B family with sequence similarity 134, member B 0.47374
SIX3 SIX homeobox 3 0.471089
PNPLA6 patatin-like phospholipase domain containing 6 0.46655
CXCR4 chemokine (C-X-C motif) receptor 4 0.462772
SACS sacsin molecular chaperone 0.460883
LIMK2 LIM domain kinase 2 0.457487
GCAT glycine C-acetyltransferase 0.454847
SP8 Sp8 transcription factor 0.453716
TXNL1 thioredoxin-like 1 0.452585
GJC2 gap junction protein, gamma 2, 47kDa 0.448064
TUBB2A tubulin, beta 2A class IIa 0.446935
MMEL1 membrane metallo-endopeptidase-like 1 0.438658
MGAM maltase-glucoamylase 0.433021
ATXN2 ataxin 2 0.427765
BDNF brain-derived neurotrophic factor 0.426265
AIF1 allograft inflammatory factor 1 0.42289
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.416896
NPTX2 neuronal pentraxin II 0.416147
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.410535
GLO1 glyoxalase I 0.407919
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.399707
PHKA2 phosphorylase kinase, alpha 2 (liver) 0.398962
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.397098
FA2H fatty acid 2-hydroxylase 0.392629
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.391141
CSF3 colony stimulating factor 3 (granulocyte) 0.384822
EGR2 early growth response 2 0.376661
TPR translocated promoter region, nuclear basket protein 0.373698
DNAH9 dynein, axonemal, heavy chain 9 0.368888
VRK1 vaccinia related kinase 1 0.362239
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 0.360026
NPY neuropeptide Y 0.354499
UBTF upstream binding transcription factor, RNA polymerase I 0.354131
CD79A CD79a molecule, immunoglobulin-associated alpha 0.35082
HEXA hexosaminidase A (alpha polypeptide) 0.350452
KLK3 kallikrein-related peptidase 3 0.350452
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.349717
MTM1 myotubularin 1 0.343106
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.339073
SCN3A sodium channel, voltage gated, type III alpha subunit 0.334681
TUBA1A tubulin, alpha 1a 0.325187
GCH1 GTP cyclohydrolase 1 0.322273
MBP myelin basic protein 0.309566
SUMF1 sulfatase modifying factor 1 0.309566
DNAH5 dynein, axonemal, heavy chain 5 0.307757
TDP1 tyrosyl-DNA phosphodiesterase 1 0.293334
ACO1 aconitase 1, soluble 0.291898
SPTBN2 spectrin, beta, non-erythrocytic 2 0.289027
EGFR epidermal growth factor receptor 0.286877
KIF5A kinesin family member 5A 0.284728
GARS glycyl-tRNA synthetase 0.283655
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.282582
TOP2B topoisomerase (DNA) II beta 180kDa 0.281153
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.280439
POLK polymerase (DNA directed) kappa 0.277227
SCP2 sterol carrier protein 2 0.265494
SOD2 superoxide dismutase 2, mitochondrial 0.263722
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.263368
TNF tumor necrosis factor 0.260538
GFAP glial fibrillary acidic protein 0.255241
DLD dihydrolipoamide dehydrogenase 0.252774
MME membrane metallo-endopeptidase 0.246098
SSTR4 somatostatin receptor 4 0.243995
HRAS Harvey rat sarcoma viral oncogene homolog 0.235964
SOX1 SRY (sex determining region Y)-box 1 0.235268
ACRV1 acrosomal vesicle protein 1 0.225229
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.221793
SGSH N-sulfoglucosamine sulfohydrolase 0.220081
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.21974
CA4 carbonic anhydrase IV 0.214297
AGO2 argonaute RISC catalytic component 2 0.213283
INSR insulin receptor 0.211597
ACTG1 actin gamma 1 0.204593
TACR2 tachykinin receptor 2 0.203604
SURF1 surfeit 1 0.200006
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.196779
SETX senataxin 0.185313
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.185016
ANK1 ankyrin 1, erythrocytic 0.182957
PSAP prosaposin 0.181798
ROM1 retinal outer segment membrane protein 1 0.180652
IFNA1 interferon, alpha 1 0.178126
GLA galactosidase, alpha 0.175679
CD68 CD68 molecule 0.171785
MYDGF myeloid-derived growth factor 0.170054
DNM2 dynamin 2 0.168854
NEFL neurofilament, light polypeptide 0.166995
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.166768
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.161716
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.160203