sensory perception of pain Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. (Gene Ontology, GO_0019233)
External Link http://amigo.geneontology.org/amigo/term/GO:0019233
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Genes

54 genes participating in the sensory perception of pain biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADRB1 adrenoceptor beta 1
ALOXE3 arachidonate lipoxygenase 3
AQP1 aquaporin 1 (Colton blood group)
BDKRB1 bradykinin receptor B1
CDK5 cyclin-dependent kinase 5
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
DLG2 discs, large homolog 2 (Drosophila)
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
FAM134B family with sequence similarity 134, member B
GIP gastric inhibitory polypeptide
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM1 glutamate receptor, metabotropic 1
HOXB8 homeobox B8
HOXD1 homeobox D1
IAPP islet amyloid polypeptide
IL12B interleukin 12B
IL1RN interleukin 1 receptor antagonist
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNK4 potassium channel, two pore domain subfamily K, member 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MECP2 methyl CpG binding protein 2
MME membrane metallo-endopeptidase
MRGPRX2 MAS-related GPR, member X2
NDN necdin, melanoma antigen (MAGE) family member
NGF nerve growth factor (beta polypeptide)
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NLGN2 neuroligin 2
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PENK proenkephalin
POMK protein-O-mannose kinase
PROK2 prokineticin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN3B sodium channel, voltage gated, type III beta subunit
TAC1 tachykinin, precursor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)