sensory neuropathy Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A peripheral neuropathy that involves damage to nerves of the peripheral nervous system. (Human Disease Ontology, DOID_2491)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000763
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Genes

96 genes associated with the sensory neuropathy phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIP aryl hydrocarbon receptor interacting protein
ALAD aminolevulinate dehydratase
AMN amnion associated transmembrane protein
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATL1 atlastin GTPase 1
ATL3 atlastin GTPase 3
ATXN8 ataxin 8
ATXN8OS ATXN8 opposite strand (non-protein coding)
C10ORF2 chromosome 10 open reading frame 2
C4A complement component 4A (Rodgers blood group)
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALR calreticulin
CASR calcium-sensing receptor
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
COMP cartilage oligomeric matrix protein
COX1
COX2
COX3
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSC cathepsin C
CUBN cubilin (intrinsic factor-cobalamin receptor)
DNASE1L3 deoxyribonuclease I-like 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
FGF14 fibroblast growth factor 14
FMR1 fragile X mental retardation 1
FXN frataxin
GAN gigaxonin
GBE1 glucan (1,4-alpha-), branching enzyme 1
GIF gastric intrinsic factor (vitamin B synthesis)
GJC2 gap junction protein, gamma 2, 47kDa
GLA galactosidase, alpha
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HBB hemoglobin, beta
HINT1 histidine triad nucleotide binding protein 1
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HMBS hydroxymethylbilane synthase
IL10 interleukin 10
IL12RB2 interleukin 12 receptor, beta 2
IL23R interleukin 23 receptor
JAK2 Janus kinase 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
LIFR leukemia inhibitory factor receptor alpha
LYST lysosomal trafficking regulator
MEFV Mediterranean fever
MFN2 mitofusin 2
MLH1 mutL homolog 1
MPL MPL proto-oncogene, thrombopoietin receptor
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MT-TF tRNA
MT-TH tRNA
MT-TL1 tRNA
MT-TQ tRNA
MT-TS1 tRNA
MT-TS2 tRNA
MT-TW tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAGA N-acetylgalactosaminidase, alpha-
ND1
NOD2 nucleotide-binding oligomerization domain containing 2
PMP22 peripheral myelin protein 22
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLG polymerase (DNA directed), gamma
PRICKLE1 prickle homolog 1 (Drosophila)
PRRT2 proline-rich transmembrane protein 2
PRTN3 proteinase 3
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB7A RAB7A, member RAS oncogene family
RNF170 ring finger protein 170
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEPT9 septin 9
SH2B3 SH2B adaptor protein 3
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SPG11 spastic paraplegia 11 (autosomal recessive)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAT4 signal transducer and activator of transcription 4
TET2 tet methylcytosine dioxygenase 2
THPO thrombopoietin
TLR4 toll-like receptor 4
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNXB tenascin XB
TP53 tumor protein p53
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)