seminiferous epithelium Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Specialised epithelium lining the seminiferous tubules containing developing and mature spermatozoa and sertoli cells. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001811)
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Genes

284 proteins co-occuring with the tissue seminiferous epithelium in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
OCLN occludin 1.77932
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.63906
CLDN11 claudin 11 1.59572
EPS8 epidermal growth factor receptor pathway substrate 8 1.4827
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 1.4575
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.43801
SHBG sex hormone-binding globulin 1.39192
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.39009
TJP1 tight junction protein 1 1.30298
PRM1 protamine 1 1.27426
ESPN espin 1.26039
CTSL cathepsin L 1.206
MTMR2 myotubularin related protein 2 1.16737
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.0996
SPEF1 sperm flagellar 1 1.09739
PVRL3 poliovirus receptor-related 3 1.09297
CREM cAMP responsive element modulator 1.09164
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.08413
PLA2G2C phospholipase A2, group IIC 1.0775
PRM2 protamine 2 1.07706
FSHR follicle stimulating hormone receptor 1.07574
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.07485
AR androgen receptor 1.07441
SPATA20 spermatogenesis associated 20 1.07441
TGFB3 transforming growth factor, beta 3 1.06515
TF transferrin 1.05677
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.04401
TUBA1A tubulin, alpha 1a 1.04181
VCY1B variable charge, Y-linked 1B 1.02294
VCY variable charge, Y-linked 1.02294
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.986294
ACRV1 acrosomal vesicle protein 1 0.982386
INHA inhibin, alpha 0.980217
PPP1R42 protein phosphatase 1, regulatory subunit 42 0.979783
GJA1 gap junction protein, alpha 1, 43kDa 0.96809
IPO5 importin 5 0.960312
KATNAL1 katanin p60 subunit A-like 1 0.955996
F11R F11 receptor 0.951685
RAB13 RAB13, member RAS oncogene family 0.934054
RNASE10 ribonuclease, RNase A family, 10 (non-active) 0.925907
PALLD palladin, cytoskeletal associated protein 0.924194
FABP12 fatty acid binding protein 12 0.91052
LDHC lactate dehydrogenase C 0.900721
CTTN cortactin 0.89562
SYCP1 synaptonemal complex protein 1 0.88671
TNP1 transition protein 1 (during histone to protamine replacement) 0.884167
CLU clusterin 0.882897
FANK1 fibronectin type III and ankyrin repeat domains 1 0.880358
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.871061
TNP2 transition protein 2 (during histone to protamine replacement) 0.846225
SORBS3 sorbin and SH3 domain containing 3 0.842447
CLDN3 claudin 3 0.838672
GFRA1 GDNF family receptor alpha 1 0.837414
SPATA18 spermatogenesis associated 18 0.829453
KLHL10 kelch-like family member 10 0.81565
STRA8 stimulated by retinoic acid 8 0.784388
MTM1 myotubularin 1 0.781478
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.777325
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.767368
PHTF1 putative homeodomain transcription factor 1 0.747927
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.743389
DNTT DNA nucleotidylexotransferase 0.733912
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.732265
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.726507
EHD1 EH-domain containing 1 0.713779
VCL vinculin 0.696172
RXFP1 relaxin/insulin-like family peptide receptor 1 0.696172
GDNF glial cell derived neurotrophic factor 0.683103
LAMC3 laminin, gamma 3 0.679025
EEA1 early endosome antigen 1 0.672913
CECR2 cat eye syndrome chromosome region, candidate 2 0.668029
CCNA1 cyclin A1 0.650154
DSPP dentin sialophosphoprotein 0.646505
CST8 cystatin 8 (cystatin-related epididymal specific) 0.63719
VEZT vezatin, adherens junctions transmembrane protein 0.627485
PARD6A par-6 family cell polarity regulator alpha 0.622235
GPX5 glutathione peroxidase 5 0.61699
SGMS2 sphingomyelin synthase 2 0.613361
GSN gelsolin 0.61175
SHKBP1 SH3KBP1 binding protein 1 0.608124
NPBWR2 neuropeptides B/W receptor 2 0.601283
RBP1 retinol binding protein 1, cellular 0.598067
ACR acrosin 0.597666
FABP9 fatty acid binding protein 9, testis 0.596862
PCNA proliferating cell nuclear antigen 0.595255
CRISP1 cysteine-rich secretory protein 1 0.595255
BAX BCL2-associated X protein 0.595255
TEX14 testis expressed 14 0.587228
PKP2 plakophilin 2 0.585625
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.578816
TRIM33 tripartite motif containing 33 0.572418
ESR1 estrogen receptor 1 0.568823
GJB3 gap junction protein, beta 3, 31kDa 0.568424
SPEF2 sperm flagellar 2 0.565631
EHD4 EH-domain containing 4 0.563238
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 0.562441
PLG plasminogen 0.556865
USP26 ubiquitin specific peptidase 26 0.553683
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.549312
CADM1 cell adhesion molecule 1 0.547326
OSTF1 osteoclast stimulating factor 1 0.544946
RAB12 RAB12, member RAS oncogene family 0.544152
RMDN3 regulator of microtubule dynamics 3 0.539396
RAB5A RAB5A, member RAS oncogene family 0.538604
VCX variable charge, X-linked 0.537812
GPX4 glutathione peroxidase 4 0.534251
VCX2 variable charge, X-linked 2 0.533065
UBC ubiquitin C 0.530693
FASLG Fas ligand (TNF superfamily, member 6) 0.530298
CADM4 cell adhesion molecule 4 0.530298
SOD2 superoxide dismutase 2, mitochondrial 0.526744
VCX3B variable charge, X-linked 3B 0.523194
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.5228
GPX1 glutathione peroxidase 1 0.522405
RPS27A ribosomal protein S27a 0.522011
TJP2 tight junction protein 2 0.519253
CLDN12 claudin 12 0.514924
CATSPER2 cation channel, sperm associated 2 0.512171
VCX3A variable charge, X-linked 3A 0.510992
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 0.509027
SYCP3 synaptonemal complex protein 3 0.506672
RESP18 regulated endocrine-specific protein 18 0.495701
CNOT7 CCR4-NOT transcription complex, subunit 7 0.494918
CLGN calmegin 0.494528
UBB ubiquitin B 0.490619
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 0.488276
DHH desert hedgehog 0.486326
WAS Wiskott-Aldrich syndrome 0.483986
DES desmin 0.482428
ZBTB16 zinc finger and BTB domain containing 16 0.474646
JAM3 junctional adhesion molecule 3 0.474258
ODF2 outer dense fiber of sperm tails 2 0.468048
GOLGA3 golgin A3 0.46766
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.467273
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.466498
HIST1H4E histone cluster 1, H4e 0.466111
HIST1H4H histone cluster 1, H4h 0.466111
HIST2H4B histone cluster 2, H4b 0.466111
HIST1H4I histone cluster 1, H4i 0.466111
HIST1H4C histone cluster 1, H4c 0.466111
HIST2H4A histone cluster 2, H4a 0.466111
HIST1H4J histone cluster 1, H4j 0.466111
HIST1H4B histone cluster 1, H4b 0.466111
HIST1H4K histone cluster 1, H4k 0.466111
HIST1H4D histone cluster 1, H4d 0.466111
HIST1H4A histone cluster 1, H4a 0.466111
HIST1H4F histone cluster 1, H4f 0.466111
ISYNA1 inositol-3-phosphate synthase 1 0.465723
MAP7 microtubule-associated protein 7 0.465335
HIST1H4L histone cluster 1, H4l 0.464561
HIST4H4 histone cluster 4, H4 0.464561
RAI14 retinoic acid induced 14 0.464174
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 0.4634
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.460692
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.45374
GDF9 growth differentiation factor 9 0.453355
CDC42 cell division cycle 42 0.447576
ZYX zyxin 0.447576
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.444499
KIF2A kinesin heavy chain member 2A 0.444115
BOK BCL2-related ovarian killer 0.442962
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.43414
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.432608
ESR2 estrogen receptor 2 (ER beta) 0.429547
AMH anti-Mullerian hormone 0.428401
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.428018
PVR poliovirus receptor 0.418099
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.417718
FTL ferritin, light polypeptide 0.413532
RAB4A RAB4A, member RAS oncogene family 0.412011
FTH1 ferritin, heavy polypeptide 1 0.409731
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.408592
ELMO1 engulfment and cell motility 1 0.408592
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.405555
POFUT1 protein O-fucosyltransferase 1 0.396844
AQP7 aquaporin 7 0.394576
GPER1 G protein-coupled estrogen receptor 1 0.389289
IL1A interleukin 1, alpha 0.385143
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 0.382884
TGFB1 transforming growth factor, beta 1 0.37687
WASH7P WAS protein family homolog 7 pseudogene 0.37687
WASH1 WAS protein family homolog 1 0.374243
STRBP spermatid perinuclear RNA binding protein 0.371994
HEXB hexosaminidase B (beta polypeptide) 0.371994
TOPBP1 topoisomerase (DNA) II binding protein 1 0.369747
WASH6P WAS protein family homolog 6 pseudogene 0.368998
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.365633
PANX3 pannexin 3 0.362646
AQP10 aquaporin 10 0.360036
BNC1 basonuclin 1 0.357058
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.355942
FST follistatin 0.348889
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.342602
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.33965
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.3356
ALPPL2 alkaline phosphatase, placental-like 2 0.33413
STRN striatin, calmodulin binding protein 0.33413
ALPL alkaline phosphatase, liver/bone/kidney 0.333763
STX11 syntaxin 11 0.333396
ALPP alkaline phosphatase, placental 0.333028
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.332294
PRND prion protein 2 (dublet) 0.327896
DNM2 dynamin 2 0.326798
RHOB ras homolog family member B 0.319863
SPAG1 sperm associated antigen 1 0.319498
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.31877
CXADR coxsackie virus and adenovirus receptor 0.316224
RXRB retinoid X receptor, beta 0.314046
UTF1 undifferentiated embryonic cell transcription factor 1 0.308974
EML1 echinoderm microtubule associated protein like 1 0.307528
BCAP31 B-cell receptor-associated protein 31 0.307167
ADGRB1 adhesion G protein-coupled receptor B1 0.304279
ACPP acid phosphatase, prostate 0.303919
TP53 tumor protein p53 0.303198
PIAS2 protein inhibitor of activated STAT, 2 0.301758
APOD apolipoprotein D 0.297089
BSG basigin (Ok blood group) 0.295297
INADL InaD-like (Drosophila) 0.294939
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.294223
GGPS1 geranylgeranyl diphosphate synthase 1 0.293508
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.293508
IRS4 insulin receptor substrate 4 0.291722
CTSD cathepsin D 0.290295
HIST2H2AC histone cluster 2, H2ac 0.290295
HIST2H2AA4 histone cluster 2, H2aa4 0.289582
HIST2H2AA3 histone cluster 2, H2aa3 0.289582
CST4 cystatin S 0.288514
PLIN2 perilipin 2 0.284253
HSPH1 heat shock 105kDa/110kDa protein 1 0.284253
SNAP91 synaptosomal-associated protein, 91kDa 0.282483
ECE2 endothelin converting enzyme 2 0.280364
SUFU suppressor of fused homolog (Drosophila) 0.273696
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.2723
TRIP10 thyroid hormone receptor interactor 10 0.269174
ILF3 interleukin enhancer binding factor 3, 90kDa 0.268137
CPB1 carboxypeptidase B1 (tissue) 0.268137
SH3GL2 SH3-domain GRB2-like 2 0.266757
CLDN1 claudin 1 0.266069
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.266069
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.265725
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.265725
ANLN anillin, actin binding protein 0.265038
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.263327
ACTB actin, beta 0.262986
PAEP progestagen-associated endometrial protein 0.262645
CLEC11A C-type lectin domain family 11, member A 0.260606
EGR4 early growth response 4 0.260606
HSPA2 heat shock 70kDa protein 2 0.257907
MSH6 mutS homolog 6 0.257907
CTNND1 catenin (cadherin-associated protein), delta 1 0.257237
HPGDS hematopoietic prostaglandin D synthase 0.251934
UBE2H ubiquitin-conjugating enzyme E2H 0.251606
SPO11 SPO11 meiotic protein covalently bound to DSB 0.247719
UBA1 ubiquitin-like modifier activating enzyme 1 0.247079
ACTG1 actin gamma 1 0.24676
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.24676
ATM ATM serine/threonine kinase 0.246124
SORBS1 sorbin and SH3 domain containing 1 0.24486
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.244232
RHBG Rh family, B glycoprotein (gene/pseudogene) 0.241438
HIST1H1T histone cluster 1, H1t 0.241438
CAT catalase 0.239307
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.238406
CATSPER1 cation channel, sperm associated 1 0.235167
PERP PERP, TP53 apoptosis effector 0.235167
DNAH8 dynein, axonemal, heavy chain 8 0.234878
CLMP CXADR-like membrane protein 0.234016
MARVELD2 MARVEL domain containing 2 0.233162
GZMK granzyme K (granzyme 3; tryptase II) 0.232317
DAZ1 deleted in azoospermia 1 0.232039
SOX8 SRY (sex determining region Y)-box 8 0.230931
HEXA hexosaminidase A (alpha polypeptide) 0.226411
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.225647
DAZ2 deleted in azoospermia 2 0.22415
JUP junction plakoglobin 0.222699
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.220831
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.219707
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.219485
ICAM2 intercellular adhesion molecule 2 0.217974
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.216528
RARG retinoic acid receptor, gamma 0.214954
FNDC3A fibronectin type III domain containing 3A 0.214388
BMP8B bone morphogenetic protein 8b 0.214017
HOXA4 homeobox A4 0.212936