seminal plasma Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The fluid portion of the semen, in which the spermatozoa are suspended. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001232)
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Genes

312 proteins co-occuring with the tissue seminal plasma in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ACR acrosin 2.3235
MSMB microseminoprotein, beta- 2.25071
KLK3 kallikrein-related peptidase 3 2.24535
SEMG1 semenogelin I 2.12033
ACPP acid phosphatase, prostate 2.10272
SEMG2 semenogelin II 1.66107
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 1.62757
PIP prolactin-induced protein 1.6136
PAEP progestagen-associated endometrial protein 1.61211
CD79A CD79a molecule, immunoglobulin-associated alpha 1.61061
CRISP3 cysteine-rich secretory protein 3 1.52712
TCP11 t-complex 11, testis-specific 1.52235
KLK2 kallikrein-related peptidase 2 1.51569
SOD2 superoxide dismutase 2, mitochondrial 1.46449
SYPL1 synaptophysin-like 1 1.42599
LTF lactotransferrin 1.41906
ALB albumin 1.40892
KLK1 kallikrein 1 1.391
CTRL chymotrypsin-like 1.35495
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.3201
TF transferrin 1.2922
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 1.28547
LDHC lactate dehydrogenase C 1.28188
NT5E 5'-nucleotidase, ecto (CD73) 1.25101
CAT catalase 1.25056
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 1.24967
ZPBP zona pellucida binding protein 1.21045
CRISP1 cysteine-rich secretory protein 1 1.18867
GPX4 glutathione peroxidase 4 1.17669
OR5R1 olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene) 1.17669
SPAG9 sperm associated antigen 9 1.17181
GPX5 glutathione peroxidase 5 1.16914
ZNRF4 zinc and ring finger 4 1.15362
GPX1 glutathione peroxidase 1 1.13944
MSH6 mutS homolog 6 1.1266
PGC progastricsin (pepsinogen C) 1.12217
VCL vinculin 1.11287
CD52 CD52 molecule 1.10314
CSN1S1 casein alpha s1 1.10225
AZU1 azurocidin 1 1.08811
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 1.08015
PLA2G1B phospholipase A2, group IB (pancreas) 1.06471
FN1 fibronectin 1 1.05765
SLPI secretory leukocyte peptidase inhibitor 1.01549
LAP3 leucine aminopeptidase 3 1.00458
CENPV centromere protein V 1.0037
EPPIN epididymal peptidase inhibitor 1.0024
ACE angiotensin I converting enzyme 0.997601
ELANE elastase, neutrophil expressed 0.990204
B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 0.97935
ALPPL2 alkaline phosphatase, placental-like 2 0.964631
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.961175
IGFBP3 insulin-like growth factor binding protein 3 0.955996
IGF1 insulin-like growth factor 1 (somatomedin C) 0.947378
KLK13 kallikrein-related peptidase 13 0.942645
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.934911
ALPL alkaline phosphatase, liver/bone/kidney 0.930193
ALPP alkaline phosphatase, placental 0.929335
PRL prolactin 0.928478
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.927621
ZNF169 zinc finger protein 169 0.9118
CD4 CD4 molecule 0.910946
NPC2 Niemann-Pick disease, type C2 0.910093
RNASEH2A ribonuclease H2, subunit A 0.899445
KLK14 kallikrein-related peptidase 14 0.89817
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.896895
ATAD2 ATPase family, AAA domain containing 2 0.892223
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.892223
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.888829
TSPO translocator protein (18kDa) 0.883744
AMH anti-Mullerian hormone 0.882474
SNAP29 synaptosomal-associated protein, 29kDa 0.875284
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.875284
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.83993
CD46 CD46 molecule, complement regulatory protein 0.830291
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.826942
SHBG sex hormone-binding globulin 0.819412
MGAM maltase-glucoamylase 0.81774
CST1 cystatin SN 0.816904
SPDYA speedy/RINGO cell cycle regulator family member A 0.814815
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.790212
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 0.776494
CPQ carboxypeptidase Q 0.77027
CLU clusterin 0.769441
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.759914
SORD sorbitol dehydrogenase 0.738442
BSPH1 binder of sperm protein homolog 1 0.736794
TES testin LIM domain protein 0.735971
CXCL8 chemokine (C-X-C motif) ligand 8 0.734323
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.726097
SPATA1 spermatogenesis associated 1 0.719524
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.705583
CST5 cystatin D 0.693311
FUCA1 fucosidase, alpha-L- 1, tissue 0.692493
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.692493
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 0.690042
PRSS8 protease, serine, 8 0.689634
CD59 CD59 molecule, complement regulatory protein 0.688817
KNG1 kininogen 1 0.68188
GGT1 gamma-glutamyltransferase 1 0.676172
DNAH8 dynein, axonemal, heavy chain 8 0.664775
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 0.663149
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.659085
CST4 cystatin S 0.645695
CST9 cystatin 9 (testatin) 0.641643
TRIM26 tripartite motif containing 26 0.640833
IL1B interleukin 1, beta 0.635572
PGF placental growth factor 0.635167
ADCY2 adenylate cyclase 2 (brain) 0.633953
FUCA2 fucosidase, alpha-L- 2, plasma 0.633549
RXFP1 relaxin/insulin-like family peptide receptor 1 0.631931
PLG plasminogen 0.62385
NGF nerve growth factor (beta polypeptide) 0.620621
KLK11 kallikrein-related peptidase 11 0.620217
GSR glutathione reductase 0.6182
TEX101 testis expressed 101 0.6182
GLIPR2 GLI pathogenesis-related 2 0.597666
DPP4 dipeptidyl-peptidase 4 0.596058
MANBA mannosidase, beta A, lysosomal 0.589635
GIMAP6 GTPase, IMAP family member 6 0.586026
PSAP prosaposin 0.584823
LDHA lactate dehydrogenase A 0.584022
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.581618
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.574017
C3 complement component 3 0.567227
KLK6 kallikrein-related peptidase 6 0.566428
IL6 interleukin 6 0.560847
LGALS3 lectin, galactoside-binding, soluble, 3 0.559652
PRM2 protamine 2 0.559254
EZR ezrin 0.558059
CST3 cystatin C 0.556467
CALCA calcitonin-related polypeptide alpha 0.551298
HEXB hexosaminidase B (beta polypeptide) 0.550901
DPP7 dipeptidyl-peptidase 7 0.547326
GUSB glucuronidase, beta 0.543359
TGFB1 transforming growth factor, beta 1 0.536229
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.530693
PLAT plasminogen activator, tissue 0.509027
HEXA hexosaminidase A (alpha polypeptide) 0.503141
MEIS2 Meis homeobox 2 0.50079
KLK4 kallikrein-related peptidase 4 0.498832
ANXA5 annexin A5 0.496874
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.494136
PTGES prostaglandin E synthase 0.4914
DEFB126 defensin, beta 126 0.475812
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.469211
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.46766
TIMP2 TIMP metallopeptidase inhibitor 2 0.463787
LYZ lysozyme 0.463013
AR androgen receptor 0.461852
FST follistatin 0.455284
DNAH14 dynein, axonemal, heavy chain 14 0.455284
DNAH12 dynein, axonemal, heavy chain 12 0.455284
KLK8 kallikrein-related peptidase 8 0.452969
GLB1 galactosidase, beta 1 0.452584
SPAG11B sperm associated antigen 11B 0.447961
TFPI2 tissue factor pathway inhibitor 2 0.447192
TNF tumor necrosis factor 0.444499
ANGPTL6 angiopoietin-like 6 0.444499
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.441426
ART5 ADP-ribosyltransferase 5 0.439507
HPN hepsin 0.43414
TMEM200C transmembrane protein 200C 0.429165
TMEM200A transmembrane protein 200A 0.429165
SMOX spermine oxidase 0.428783
CAMP cathelicidin antimicrobial peptide 0.42649
LNPEP leucyl/cystinyl aminopeptidase 0.426109
GSTA1 glutathione S-transferase alpha 1 0.426109
ZP3 zona pellucida glycoprotein 3 (sperm receptor) 0.418861
HTRA2 HtrA serine peptidase 2 0.41848
CATSPER1 cation channel, sperm associated 1 0.417337
RPSA ribosomal protein SA 0.415053
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.411251
SGPL1 sphingosine-1-phosphate lyase 1 0.407832
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.406315
ANPEP alanyl (membrane) aminopeptidase 0.404797
HGFAC HGF activator 0.401386
PARK7 parkinson protein 7 0.40025
DNAH5 dynein, axonemal, heavy chain 5 0.40025
SP3 Sp3 transcription factor 0.398735
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.397222
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.397222
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.396844
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.396087
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.395709
IGFBP1 insulin-like growth factor binding protein 1 0.390044
GSTA3 glutathione S-transferase alpha 3 0.389666
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 0.389289
GSTA4 glutathione S-transferase alpha 4 0.387781
GSTA2 glutathione S-transferase alpha 2 0.387404
CTSH cathepsin H 0.38665
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.374618
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.373118
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.370496
NPPC natriuretic peptide C 0.369747
CRAT carnitine O-acetyltransferase 0.367502
CES5A carboxylesterase 5A 0.366754
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.363766
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.362646
LDHAL6B lactate dehydrogenase A-like 6B 0.360036
ANXA4 annexin A4 0.359664
CP ceruloplasmin (ferroxidase) 0.357802
TGM4 transglutaminase 4 0.357058
MRC1 mannose receptor, C type 1 0.355198
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.347038
PROK2 prokineticin 2 0.346668
RXFP2 relaxin/insulin-like family peptide receptor 2 0.345188
DNAH9 dynein, axonemal, heavy chain 9 0.344079
GSTM1 glutathione S-transferase mu 1 0.341863
NKX1-1 NK1 homeobox 1 0.338914
TRH thyrotropin-releasing hormone 0.332661
NUCB1 nucleobindin 1 0.331194
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.328994
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.326798
KIF22 kinesin family member 22 0.324239
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.322414
PLAU plasminogen activator, urokinase 0.321685
IL10 interleukin 10 0.32132
HSPA4 heat shock 70kDa protein 4 0.32132
POMC proopiomelanocortin 0.319863
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.319863
IL2 interleukin 2 0.319498
HIST2H2BF histone cluster 2, H2bf 0.319134
HIST3H2BB histone cluster 3, H2bb 0.319134
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.31877
HIST1H2BH histone cluster 1, H2bh 0.318407
TGM3 transglutaminase 3 0.318042
CTSG cathepsin G 0.317679
HIST1H2BD histone cluster 1, H2bd 0.317679
A2M alpha-2-macroglobulin 0.316951
PI3 peptidase inhibitor 3, skin-derived 0.316588
CTSC cathepsin C 0.314409
HIST1H2BA histone cluster 1, H2ba 0.313683
CTSB cathepsin B 0.31332
SCGB1D2 secretoglobin, family 1D, member 2 0.312232
FCGBP Fc fragment of IgG binding protein 0.309335
PEBP1 phosphatidylethanolamine binding protein 1 0.306083
C21ORF2 chromosome 21 open reading frame 2 0.304279
HIST1H2BF histone cluster 1, H2bf 0.300679
HIST1H2BC histone cluster 1, H2bc 0.300679
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.300679
PEBP4 phosphatidylethanolamine-binding protein 4 0.30032
SPP1 secreted phosphoprotein 1 0.29996
ADM adrenomedullin 0.296372
FETUB fetuin B 0.295297
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.290652
SOD3 superoxide dismutase 3, extracellular 0.289226
PREP prolyl endopeptidase 0.28887
AKR1C3 aldo-keto reductase family 1, member C3 0.287803
MUC20 mucin 20, cell surface associated 0.287447
ZFYVE9 zinc finger, FYVE domain containing 9 0.284253
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.283191
NCOA4 nuclear receptor coactivator 4 0.282483
GPI glucose-6-phosphate isomerase 0.281423
LDHAL6A lactate dehydrogenase A-like 6A 0.278603
CPE carboxypeptidase E 0.277197
HSPA14 heat shock 70kDa protein 14 0.275094
INSL6 insulin-like 6 0.273696
FOXP3 forkhead box P3 0.269174
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.265725
CST2 cystatin SA 0.263669
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.262986
LEP leptin 0.259929
CCL3 chemokine (C-C motif) ligand 3 0.259591
ARSA arylsulfatase A 0.255567
IFI30 interferon, gamma-inducible protein 30 0.255234
ATP11A ATPase, class VI, type 11A 0.253578
KIAA0101 KIAA0101 0.250953
PBRM1 polybromo 1 0.24676
MUC6 mucin 6, oligomeric mucus/gel-forming 0.244232
PDIA3 protein disulfide isomerase family A, member 3 0.242363
PSG8 pregnancy specific beta-1-glycoprotein 8 0.241438
CCNK cyclin K 0.238406
SAMD11 sterile alpha motif domain containing 11 0.238108
CELA2A chymotrypsin-like elastase family, member 2A 0.237513
GCOM1 GRINL1A complex locus 1 0.236627
NUP88 nucleoporin 88kDa 0.23604
INSL5 insulin-like 5 0.235167
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.23459
LEPR leptin receptor 0.233731
TGM1 transglutaminase 1 0.232881
AK1 adenylate kinase 1 0.232599
CCL20 chemokine (C-C motif) ligand 20 0.232317
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.232317
CPB1 carboxypeptidase B1 (tissue) 0.230931
B2M beta-2-microglobulin 0.230656
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.228497
GSTM5 glutathione S-transferase mu 5 0.226667
PLBD2 phospholipase B domain containing 2 0.226667
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.225647
LMAN1 lectin, mannose-binding, 1 0.224645
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.224645
CAMKV CaM kinase-like vesicle-associated 0.224398
CDSN corneodesmosin 0.224398
PSCA prostate stem cell antigen 0.22415
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.223419
ADA adenosine deaminase 0.220604
F3 coagulation factor III (thromboplastin, tissue factor) 0.220152
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.219047
USP1 ubiquitin specific peptidase 1 0.219047
MME membrane metallo-endopeptidase 0.218186
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.218186
APOA1 apolipoprotein A-I 0.217139
GAN gigaxonin 0.216126
RBMS2 RNA binding motif, single stranded interacting protein 2 0.215147
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.214388
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.214388
CD209 CD209 molecule 0.214017
XYLT2 xylosyltransferase II 0.213471
TKTL1 transketolase-like 1 0.213112
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.212413
ENO1 enolase 1, (alpha) 0.212413