second-messenger-mediated signaling Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell. (Gene Ontology, GO_0019932)
External Link http://amigo.geneontology.org/amigo/term/GO:0019932
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Genes

131 genes participating in the second-messenger-mediated signaling biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADGRL1 adhesion G protein-coupled receptor L1
ADM adrenomedullin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKAP6 A kinase (PRKA) anchor protein 6
ANK2 ankyrin 2, neuronal
APOE apolipoprotein E
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AVPR1A arginine vasopressin receptor 1A
BCAP31 B-cell receptor-associated protein 31
BHLHA15 basic helix-loop-helix family, member a15
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CCL3 chemokine (C-C motif) ligand 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD36 CD36 molecule (thrombospondin receptor)
CLIC2 chloride intracellular channel 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DGKD diacylglycerol kinase, delta 130kDa
DGKQ diacylglycerol kinase, theta 110kDa
DMD dystrophin
DMTN dematin actin binding protein
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EPHA5 EPH receptor A5
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP1B FK506 binding protein 1B, 12.6 kDa
FPR1 formyl peptide receptor 1
GAL galanin/GMAP prepropeptide
GCK glucokinase (hexokinase 4)
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GLP1R glucagon-like peptide 1 receptor
GPR143 G protein-coupled receptor 143
GPRC6A G protein-coupled receptor, class C, group 6, member A
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTO1 glutathione S-transferase omega 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HDAC4 histone deacetylase 4
HOMER2 homer scaffolding protein 2
HRC histidine rich calcium binding protein
HRH1 histamine receptor H1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KDR kinase insert domain receptor
KISS1R KISS1 receptor
LACRT lacritin
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAPK7 mitogen-activated protein kinase 7
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MCU mitochondrial calcium uniporter
MRVI1 murine retrovirus integration site 1 homolog
MT1X metallothionein 1X
NCALD neurocalcin delta
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NEUROD1 neuronal differentiation 1
NMUR1 neuromedin U receptor 1
NMUR2 neuromedin U receptor 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY2R neuropeptide Y receptor Y2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PCLO piccolo presynaptic cytomatrix protein
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE4D phosphodiesterase 4D, cAMP-specific
PDE9A phosphodiesterase 9A
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PDZD3 PDZ domain containing 3
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLN phospholamban
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PTGDR2 prostaglandin D2 receptor 2
PTGFR prostaglandin F receptor (FP)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASD1 RAS, dexamethasone-induced 1
RCAN1 regulator of calcineurin 1
RCAN2 regulator of calcineurin 2
RCAN3 RCAN family member 3
RIMS2 regulating synaptic membrane exocytosis 2
RYR2 ryanodine receptor 2 (cardiac)
SELE selectin E
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
TBXA2R thromboxane A2 receptor
TFF2 trefoil factor 2
TNF tumor necrosis factor
VSNL1 visinin-like 1