scriptaid-6901 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the scriptaid-6901 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AHNAK2 AHNAK nucleoprotein 2
AHR aryl hydrocarbon receptor
APP amyloid beta (A4) precursor protein
ARMCX2 armadillo repeat containing, X-linked 2
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BEX4 brain expressed, X-linked 4
C16ORF45 chromosome 16 open reading frame 45
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC28A coiled-coil domain containing 28A
CD302 CD302 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CORO1A coronin, actin binding protein, 1A
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
CYLD cylindromatosis (turban tumor syndrome)
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DENND3 DENN/MADD domain containing 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPYSL4 dihydropyrimidinase-like 4
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GEM GTP binding protein overexpressed in skeletal muscle
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLCE glucuronic acid epimerase
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
GRK5 G protein-coupled receptor kinase 5
GSDMB gasdermin B
GTF2B general transcription factor IIB
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INSIG1 insulin induced gene 1
KIAA0895 KIAA0895
KIF21B kinesin family member 21B
LIMA1 LIM domain and actin binding 1
LMBR1L limb development membrane protein 1-like
LYST lysosomal trafficking regulator
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP2K3 mitogen-activated protein kinase kinase 3
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MUC3B mucin 3B, cell surface associated
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPC1 Niemann-Pick disease, type C1
NUP62CL nucleoporin 62kDa C-terminal like
OASL 2'-5'-oligoadenylate synthetase-like
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PDE4DIP phosphodiesterase 4D interacting protein
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLLP plasmolipin
PLXNA3 plexin A3
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
RAB29 RAB29, member RAS oncogene family
RAB40B RAB40B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RIMS3 regulating synaptic membrane exocytosis 3
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL3L ribosomal protein L3-like
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RTN2 reticulon 2
RUNDC3B RUN domain containing 3B
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SH3GL3 SH3-domain GRB2-like 3
SIRT4 sirtuin 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNN stannin
STK17A serine/threonine kinase 17a
STON1 stonin 1
SYT11 synaptotagmin XI
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
WDR19 WD repeat domain 19
WDR47 WD repeat domain 47
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADNP activity-dependent neuroprotector homeobox
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMIGO2 adhesion molecule with Ig-like domain 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAK1 BCL2-antagonist/killer 1
BANP BTG3 associated nuclear protein
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCAR3 breast cancer anti-estrogen resistance 3
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF106 chromosome 1 open reading frame 106
C9ORF91 chromosome 9 open reading frame 91
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCND1 cyclin D1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
COA7 cytochrome c oxidase assembly factor 7 (putative)
COIL coilin
CTCF CCCTC-binding factor (zinc finger protein)
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DEAF1 DEAF1 transcription factor
DENND2D DENN/MADD domain containing 2D
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DUSP4 dual specificity phosphatase 4
EFNA1 ephrin-A1
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
EXOSC10 exosome component 10
FAM57A family with sequence similarity 57, member A
FJX1 four jointed box 1 (Drosophila)
FOXA1 forkhead box A1
FOXC1 forkhead box C1
GABPB1 GA binding protein transcription factor, beta subunit 1
GATA3 GATA binding protein 3
GTF2IRD1 GTF2I repeat domain containing 1
H2AFY2 H2A histone family, member Y2
HIRA histone cell cycle regulator
HIRIP3 HIRA interacting protein 3
HP1BP3 heterochromatin protein 1, binding protein 3
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRX5 iroquois homeobox 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCTD15 potassium channel tetramerization domain containing 15
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCNT pericentrin
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLK1 polo-like kinase 1
POGK pogo transposable element with KRAB domain
PP14571 uncharacterized LOC100130449
PRR15L proline rich 15-like
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RGS19 regulator of G-protein signaling 19
SCRN1 secernin 1
SLC35F2 solute carrier family 35, member F2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG20 small nucleolar RNA host gene 20
SNUPN snurportin 1
SREK1 splicing regulatory glutamine/lysine-rich protein 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFB3 transforming growth factor, beta 3
TMEM30B transmembrane protein 30B
TOE1 target of EGR1, member 1 (nuclear)
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
UBL4A ubiquitin-like 4A
UBTF upstream binding transcription factor, RNA polymerase I
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZC3H4 zinc finger CCCH-type containing 4
ZHX2 zinc fingers and homeoboxes 2
ZIC1 Zic family member 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692