scopolamine N-oxide-5436 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the scopolamine N-oxide-5436 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAP2 ArfGAP with dual PH domains 2
ALOX5 arachidonate 5-lipoxygenase
ANGPTL2 angiopoietin-like 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOM apolipoprotein M
ARMCX4 armadillo repeat containing, X-linked 4
ARNT aryl hydrocarbon receptor nuclear translocator
ASPN asporin
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BIN1 bridging integrator 1
BMP5 bone morphogenetic protein 5
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C14ORF79 chromosome 14 open reading frame 79
CASR calcium-sensing receptor
CCRL2 chemokine (C-C motif) receptor-like 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CES1 carboxylesterase 1
CLTA clathrin, light chain A
COL5A1 collagen, type V, alpha 1
DIO2 deiodinase, iodothyronine, type II
DOCK5 dedicator of cytokinesis 5
DPF1 D4, zinc and double PHD fingers family 1
DRD1 dopamine receptor D1
EPHA1 EPH receptor A1
ERC2-IT1 ERC2 intronic transcript 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXN2 forkhead box N2
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD1 frizzled class receptor 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GK glycerol kinase
GLS glutaminase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HDAC7 histone deacetylase 7
HIST1H3J histone cluster 1, H3j
HOXA6 homeobox A6
IFI6 interferon, alpha-inducible protein 6
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IQCC IQ motif containing C
IQCK IQ motif containing K
JAG1 jagged 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIF21B kinesin family member 21B
KLF13 Kruppel-like factor 13
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTB4R leukotriene B4 receptor
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED28 mediator complex subunit 28
MMP11 matrix metallopeptidase 11
MOBP myelin-associated oligodendrocyte basic protein
MR1 major histocompatibility complex, class I-related
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MZF1 myeloid zinc finger 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PADI1 peptidyl arginine deiminase, type I
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PILRA paired immunoglobin-like type 2 receptor alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PML promyelocytic leukemia
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRAMEF11 PRAME family member 11
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAP2B RAP2B, member of RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RPL35A ribosomal protein L35a
SARM1 sterile alpha and TIR motif containing 1
SFTPB surfactant protein B
SHOX2 short stature homeobox 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35E2 solute carrier family 35, member E2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS6 suppressor of cytokine signaling 6
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STYK1 serine/threonine/tyrosine kinase 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNC syncoilin, intermediate filament protein
TAGLN3 transgelin 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TICAM1 toll-like receptor adaptor molecule 1
TMPRSS6 transmembrane protease, serine 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRD T cell receptor delta locus
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULBP1 UL16 binding protein 1
XIST X inactive specific transcript (non-protein coding)
ZC3H13 zinc finger CCCH-type containing 13
ZNF204P zinc finger protein 204, pseudogene
ZNF407 zinc finger protein 407
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY7 adenylate cyclase 7
ADRA2C adrenoceptor alpha 2C
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C1QTNF3 C1q and tumor necrosis factor related protein 3
C8ORF60 chromosome 8 open reading frame 60
CBX8 chromobox homolog 8
CCNO cyclin O
CDR2L cerebellar degeneration-related protein 2-like
CES3 carboxylesterase 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCF1 cardiotrophin-like cytokine factor 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRY2 cryptochrome circadian clock 2
DBF4B DBF4 zinc finger B
DGAT1 diacylglycerol O-acyltransferase 1
DSCAM Down syndrome cell adhesion molecule
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FADS2 fatty acid desaturase 2
FANCE Fanconi anemia, complementation group E
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ22184
FLT4 fms-related tyrosine kinase 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GBP2 guanylate binding protein 2, interferon-inducible
GMEB1 glucocorticoid modulatory element binding protein 1
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H2AJ histone cluster 1, H2aj
IGFBP6 insulin-like growth factor binding protein 6
IL15RA interleukin 15 receptor, alpha
INPP5J inositol polyphosphate-5-phosphatase J
IQCG IQ motif containing G
KLHL28 kelch-like family member 28
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP2 low density lipoprotein receptor-related protein 2
MAP1S microtubule-associated protein 1S
MAPKBP1 mitogen-activated protein kinase binding protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MRPS18C mitochondrial ribosomal protein S18C
MUC3A mucin 3A, cell surface associated
NDRG1 N-myc downstream regulated 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NRSN2 neurensin 2
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PCDHA6 protocadherin alpha 6
PNKP polynucleotide kinase 3'-phosphatase
PODNL1 podocan-like 1
PRKCE protein kinase C, epsilon
RFTN1 raftlin, lipid raft linker 1
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SENP7 SUMO1/sentrin specific peptidase 7
SLC12A8 solute carrier family 12, member 8
SLN sarcolipin
SMIM14 small integral membrane protein 14
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
STRA6 stimulated by retinoic acid 6
SYCP2 synaptonemal complex protein 2
TGFBR3 transforming growth factor, beta receptor III
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XYLT2 xylosyltransferase II
ZNF205 zinc finger protein 205
ZNF480 zinc finger protein 480
ZNF701 zinc finger protein 701
ZNF816 zinc finger protein 816