scopolamine N-oxide-2262 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the scopolamine N-oxide-2262 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACVR1B activin A receptor, type IB
ANK1 ankyrin 1, erythrocytic
ARPIN actin-related protein 2/3 complex inhibitor
ATG10 autophagy related 10
BCAP29 B-cell receptor-associated protein 29
C1ORF54 chromosome 1 open reading frame 54
C1ORF61 chromosome 1 open reading frame 61
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM4 cell adhesion molecule 4
CD4 CD4 molecule
CDRT1 CMT1A duplicated region transcript 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CELF2 CUGBP, Elav-like family member 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CREBBP CREB binding protein
CTBP2 C-terminal binding protein 2
CTSF cathepsin F
CXCL6 chemokine (C-X-C motif) ligand 6
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DMPK dystrophia myotonica-protein kinase
DNASE1L3 deoxyribonuclease I-like 3
EMC3 ER membrane protein complex subunit 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM76A family with sequence similarity 76, member A
FBLN1 fibulin 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FSCN3 fascin actin-bundling protein 3, testicular
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GINS4 GINS complex subunit 4 (Sld5 homolog)
GOLGA8A golgin A8 family, member A
GP1BB glycoprotein Ib (platelet), beta polypeptide
GP5 glycoprotein V (platelet)
GREB1 growth regulation by estrogen in breast cancer 1
HDAC5 histone deacetylase 5
HIST1H1D histone cluster 1, H1d
HRH3 histamine receptor H3
IL22 interleukin 22
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
JUN jun proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0125 KIAA0125
KIAA1456 KIAA1456
KSR1 kinase suppressor of ras 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPIN2 lipin 2
LPP LIM domain containing preferred translocation partner in lipoma
LRRN3 leucine rich repeat neuronal 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MED18 mediator complex subunit 18
MINK1 misshapen-like kinase 1
MOXD1 monooxygenase, DBH-like 1
MT3 metallothionein 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRF1L mitochondrial translational release factor 1-like
NOP16 NOP16 nucleolar protein
NPR3 natriuretic peptide receptor 3
NRG1 neuregulin 1
NUDCD3 NudC domain containing 3
NUP54 nucleoporin 54kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4D phosphodiesterase 4D, cAMP-specific
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PHTF2 putative homeodomain transcription factor 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRX periaxin
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRR protein tyrosine phosphatase, receptor type, R
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMS3 RNA binding motif, single stranded interacting protein 3
RUNX1 runt-related transcription factor 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SKIL SKI-like proto-oncogene
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLIT1 slit homolog 1 (Drosophila)
STX7 syntaxin 7
SYK spleen tyrosine kinase
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX5 T-box 5
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TFDP3 transcription factor Dp family, member 3
TM4SF4 transmembrane 4 L six family member 4
TMEM63A transmembrane protein 63A
TP53I11 tumor protein p53 inducible protein 11
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUBBP5 tubulin, beta pseudogene 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UHRF1BP1L UHRF1 binding protein 1-like
USP36 ubiquitin specific peptidase 36
WSB1 WD repeat and SOCS box containing 1
ZCCHC4 zinc finger, CCHC domain containing 4
ZFP64 ZFP64 zinc finger protein
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ANXA2P3 annexin A2 pseudogene 3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB2 arrestin, beta 2
ATAD3A ATPase family, AAA domain containing 3A
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BATF basic leucine zipper transcription factor, ATF-like
C11ORF80 chromosome 11 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CBX4 chromobox homolog 4
CCP110 centriolar coiled coil protein 110kDa
CNTN1 contactin 1
CORO7 coronin 7
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EFNA3 ephrin-A3
EMID1 EMI domain containing 1
FAM120C family with sequence similarity 120C
FAM204A family with sequence similarity 204, member A
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
GALK1 galactokinase 1
GLRA1 glycine receptor, alpha 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRB7 growth factor receptor-bound protein 7
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KIAA0754 KIAA0754
KLHDC8A kelch domain containing 8A
LAMA3 laminin, alpha 3
LIF leukemia inhibitory factor
LY6G6C lymphocyte antigen 6 complex, locus G6C
MCC mutated in colorectal cancers
MED15 mediator complex subunit 15
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MSI1 musashi RNA-binding protein 1
MT1H metallothionein 1H
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
NXPH4 neurexophilin 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OTUD3 OTU deubiquitinase 3
PCDHB8 protocadherin beta 8
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PITX2 paired-like homeodomain 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
PSD4 pleckstrin and Sec7 domain containing 4
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3A RAB3A, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SIL1 SIL1 nucleotide exchange factor
SIX1 SIX homeobox 1
SKI SKI proto-oncogene
SLC22A14 solute carrier family 22, member 14
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNTA1 syntrophin, alpha 1
SNX15 sorting nexin 15
ST5 suppression of tumorigenicity 5
STARD3 StAR-related lipid transfer (START) domain containing 3
SUN2 Sad1 and UNC84 domain containing 2
TAOK1 TAO kinase 1
TBKBP1 TBK1 binding protein 1
TCTN1 tectonic family member 1
TOLLIP toll interacting protein
TOM1 target of myb1 (chicken)
TRIM36 tripartite motif containing 36
TSPAN14 tetraspanin 14
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
YY2 YY2 transcription factor
ZNF10 zinc finger protein 10
ZNF574 zinc finger protein 574
ZNF76 zinc finger protein 76