scopolamine N-oxide-2099 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the scopolamine N-oxide-2099 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACOX3 acyl-CoA oxidase 3, pristanoyl
AGTR1 angiotensin II receptor, type 1
AKAP17A A kinase (PRKA) anchor protein 17A
ALPK1 alpha-kinase 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
CCDC88A coiled-coil domain containing 88A
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD22 CD22 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP290 centrosomal protein 290kDa
CFAP45 cilia and flagella associated protein 45
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPT1A carnitine palmitoyltransferase 1A (liver)
DEPDC5 DEP domain containing 5
DHRS9 dehydrogenase/reductase (SDR family) member 9
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESRRA estrogen-related receptor alpha
EVA1B eva-1 homolog B (C. elegans)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FASTKD2 FAST kinase domains 2
FBXO21 F-box protein 21
FNBP1 formin binding protein 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL3ST4 galactose-3-O-sulfotransferase 4
GIF gastric intrinsic factor (vitamin B synthesis)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCRTR1 hypocretin (orexin) receptor 1
HOOK1 hook microtubule-tethering protein 1
HOXA11 homeobox A11
IFT140 intraflagellar transport 140
IL1RN interleukin 1 receptor antagonist
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCTD17 potassium channel tetramerization domain containing 17
KRIT1 KRIT1, ankyrin repeat containing
LRRC40 leucine rich repeat containing 40
LRRC8B leucine rich repeat containing 8 family, member B
MAPRE3 microtubule-associated protein, RP/EB family, member 3
METTL5 methyltransferase like 5
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTSS1L metastasis suppressor 1-like
NEK3 NIMA-related kinase 3
NF1 neurofibromin 1
NOL12 nucleolar protein 12
NOP16 NOP16 nucleolar protein
NOVA2 neuro-oncological ventral antigen 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
PALM paralemmin
PDLIM3 PDZ and LIM domain 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
POLL polymerase (DNA directed), lambda
PRPH peripherin
RAB31 RAB31, member RAS oncogene family
RAD51B RAD51 paralog B
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBL2 retinoblastoma-like 2
REN renin
REST RE1-silencing transcription factor
RFPL1 ret finger protein-like 1
RGS10 regulator of G-protein signaling 10
ROR1 receptor tyrosine kinase-like orphan receptor 1
RRAD Ras-related associated with diabetes
RREB1 ras responsive element binding protein 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A3 S100 calcium binding protein A3
SCARB1 scavenger receptor class B, member 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A4 solute carrier family 16, member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTB spectrin, beta, erythrocytic
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUSD4 sushi domain containing 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAZ tafazzin
TBC1D2B TBC1 domain family, member 2B
TBX19 T-box 19
TLE3 transducin-like enhancer of split 3
TLK1 tousled-like kinase 1
TMEM180 transmembrane protein 180
TMEM63A transmembrane protein 63A
TRIM25 tripartite motif containing 25
VDAC3 voltage-dependent anion channel 3
WSB1 WD repeat and SOCS box containing 1
YTHDC2 YTH domain containing 2
ZBTB43 zinc finger and BTB domain containing 43
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP30 ZFP30 zinc finger protein
ZNF37BP zinc finger protein 37B, pseudogene
ZNF816 zinc finger protein 816

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACYP1 acylphosphatase 1, erythrocyte (common) type
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALS2CL ALS2 C-terminal like
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL14 ADP-ribosylation factor-like 14
BAK1 BCL2-antagonist/killer 1
BNC1 basonuclin 1
C16ORF45 chromosome 16 open reading frame 45
C16ORF62 chromosome 16 open reading frame 62
C1ORF105 chromosome 1 open reading frame 105
CDK9 cyclin-dependent kinase 9
CEP131 centrosomal protein 131kDa
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO1A coronin, actin binding protein, 1A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSD cathepsin D
CUL9 cullin 9
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDN1 endothelin 1
ETAA1 Ewing tumor-associated antigen 1
FBXL7 F-box and leucine-rich repeat protein 7
FBXO46 F-box protein 46
FZD3 frizzled class receptor 3
GCA grancalcin, EF-hand calcium binding protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRPR gastrin-releasing peptide receptor
HP1BP3 heterochromatin protein 1, binding protein 3
ICK intestinal cell (MAK-like) kinase
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT81 intraflagellar transport 81
IGFLR1 IGF-like family receptor 1
IL17RB interleukin 17 receptor B
IRF2 interferon regulatory factor 2
ITPKB inositol-trisphosphate 3-kinase B
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM4D lysine (K)-specific demethylase 4D
KIAA0894 KIAA0894 protein
KIAA1549L KIAA1549-like
MCMBP minichromosome maintenance complex binding protein
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MTERF1 mitochondrial transcription termination factor 1
MX1 MX dynamin-like GTPase 1
NBEAL2 neurobeachin-like 2
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSD1 nuclear receptor binding SET domain protein 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PEX6 peroxisomal biogenesis factor 6
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC8 placenta-specific 8
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTGFR prostaglandin F receptor (FP)
RIN1 Ras and Rab interactor 1
RNF25 ring finger protein 25
RNF31 ring finger protein 31
SCAMP4 secretory carrier membrane protein 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3BGR SH3 domain binding glutamate-rich protein
SHROOM2 shroom family member 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STAC SH3 and cysteine rich domain
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THBS3 thrombospondin 3
TMEM183A transmembrane protein 183A
TNNI3 troponin I type 3 (cardiac)
TOR4A torsin family 4, member A
TUBA3C tubulin, alpha 3c
TXLNG taxilin gamma
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA1 von Willebrand factor A domain containing 1
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H12A zinc finger CCCH-type containing 12A
ZMYM1 zinc finger, MYM-type 1
ZNF426 zinc finger protein 426
ZNF701 zinc finger protein 701
ZNF862 zinc finger protein 862