scopolamine N-oxide-1415 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the scopolamine N-oxide-1415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF2 AF4/FMR2 family, member 2
AGRN agrin
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AMN amnion associated transmembrane protein
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP10 Rho GTPase activating protein 10
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAX BCL2-associated X protein
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C4BPA complement component 4 binding protein, alpha
CCDC64 coiled-coil domain containing 64
CD177 CD177 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CLTA clathrin, light chain A
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DDR1 discoidin domain receptor tyrosine kinase 1
DMBT1 deleted in malignant brain tumors 1
DUS2 dihydrouridine synthase 2
E2F1 E2F transcription factor 1
EGR4 early growth response 4
FAM134B family with sequence similarity 134, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF4 fibroblast growth factor 4
FGL1 fibrinogen-like 1
FHL1 four and a half LIM domains 1
FLOT2 flotillin 2
FOLR1 folate receptor 1 (adult)
FRMD8 FERM domain containing 8
GFOD2 glucose-fructose oxidoreductase domain containing 2
GHRHR growth hormone releasing hormone receptor
GIPC1 GIPC PDZ domain containing family, member 1
GJB1 gap junction protein, beta 1, 32kDa
GJB3 gap junction protein, beta 3, 31kDa
GLI3 GLI family zinc finger 3
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HOXA4 homeobox A4
HP1BP3 heterochromatin protein 1, binding protein 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
KDM6B lysine (K)-specific demethylase 6B
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAD1 ladinin 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMNA lamin A/C
LRRC37A2 leucine rich repeat containing 37, member A2
MAGED2 melanoma antigen family D2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MET MET proto-oncogene, receptor tyrosine kinase
MICALL2 MICAL-like 2
MINK1 misshapen-like kinase 1
MISP mitotic spindle positioning
MMP19 matrix metallopeptidase 19
MYO1C myosin IC
MYO7A myosin VIIA
N4BP3 NEDD4 binding protein 3
NADK NAD kinase
NCR2 natural cytotoxicity triggering receptor 2
NDRG2 NDRG family member 2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PARD3 par-3 family cell polarity regulator
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PEX14 peroxisomal biogenesis factor 14
PILRA paired immunoglobin-like type 2 receptor alpha
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PSD4 pleckstrin and Sec7 domain containing 4
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRT protein tyrosine phosphatase, receptor type, T
PZP pregnancy-zone protein
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RBFA ribosome binding factor A (putative)
RUNX1 runt-related transcription factor 1
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
STAT4 signal transducer and activator of transcription 4
SVIL supervillin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBXA2R thromboxane A2 receptor
TCP11L1 t-complex 11, testis-specific-like 1
TLR5 toll-like receptor 5
TMEM120B transmembrane protein 120B
TMEM74B transmembrane protein 74B
TMSB4Y thymosin beta 4, Y-linked
TPM3 tropomyosin 3
TRABD TraB domain containing
TRIM62 tripartite motif containing 62
TSPAN32 tetraspanin 32
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VGF VGF nerve growth factor inducible
XYLT2 xylosyltransferase II
ZC4H2 zinc finger, C4H2 domain containing
ZNF280A zinc finger protein 280A
ZNF337 zinc finger protein 337
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADORA3 adenosine A3 receptor
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD11 ankyrin repeat domain 11
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
BCL10 B-cell CLL/lymphoma 10
BRIX1 BRX1, biogenesis of ribosomes
CASD1 CAS1 domain containing 1
CDC37L1 cell division cycle 37-like 1
CHMP3 charged multivesicular body protein 3
CISD1 CDGSH iron sulfur domain 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4 DBF4 zinc finger
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEAF1 DEAF1 transcription factor
DENND4A DENN/MADD domain containing 4A
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DOLPP1 dolichyldiphosphatase 1
ENAH enabled homolog (Drosophila)
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ERCC2 excision repair cross-complementation group 2
FAM172A family with sequence similarity 172, member A
FAM57A family with sequence similarity 57, member A
FBXW4 F-box and WD repeat domain containing 4
GMPPB GDP-mannose pyrophosphorylase B
GOLM1 golgi membrane protein 1
GPATCH1 G patch domain containing 1
GPR63 G protein-coupled receptor 63
GRM4 glutamate receptor, metabotropic 4
GRWD1 glutamate-rich WD repeat containing 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
IGKV1D-13 immunoglobulin kappa variable 1D-13
IMPAD1 inositol monophosphatase domain containing 1
ISCU iron-sulfur cluster assembly enzyme
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD3 potassium channel tetramerization domain containing 3
KIFC1 kinesin family member C1
LBR lamin B receptor
LINC00339 long intergenic non-protein coding RNA 339
LTN1 listerin E3 ubiquitin protein ligase 1
MAGEF1 melanoma antigen family F1
MAP1S microtubule-associated protein 1S
METTL18 methyltransferase like 18
MEX3C mex-3 RNA binding family member C
MIS18BP1 MIS18 binding protein 1
MOB3B MOB kinase activator 3B
MPHOSPH8 M-phase phosphoprotein 8
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NFE2L2 nuclear factor, erythroid 2-like 2
NRBF2 nuclear receptor binding factor 2
NRGN neurogranin (protein kinase C substrate, RC3)
NSD1 nuclear receptor binding SET domain protein 1
NUP93 nucleoporin 93kDa
NXPH3 neurexophilin 3
OPHN1 oligophrenin 1
PAK1IP1 PAK1 interacting protein 1
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PID1 phosphotyrosine interaction domain containing 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PNRC1 proline-rich nuclear receptor coactivator 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PRPF39 pre-mRNA processing factor 39
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RABL3 RAB, member of RAS oncogene family-like 3
RNASE6 ribonuclease, RNase A family, k6
RPL34 ribosomal protein L34
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SATB1 SATB homeobox 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SFXN1 sideroflexin 1
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNHG3 small nucleolar RNA host gene 3
STAR steroidogenic acute regulatory protein
STAU2 staufen double-stranded RNA binding protein 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF3 transmembrane 7 superfamily member 3
TM9SF2 transmembrane 9 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM4 transmembrane BAX inhibitor motif containing 4
TNRC6B trinucleotide repeat containing 6B
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
UBXN2B UBX domain protein 2B
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
YEATS4 YEATS domain containing 4
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZNF23 zinc finger protein 23
ZNF536 zinc finger protein 536
ZNF8 zinc finger protein 8