schizophrenia Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. (Human Disease Ontology, DOID_5419)
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Genes

131 genes associated with the disease schizophrenia in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRIM26 tripartite motif containing 26 1.17894
POM121L2 POM121 transmembrane nucleoporin-like 2 0.894262
NKAPL NFKB activating protein-like 0.830123
TSPAN18 tetraspanin 18 0.817078
DPYD dihydropyrimidine dehydrogenase 0.790827
LSM1 LSM1, U6 small nuclear RNA associated 0.724323
NOTCH4 notch 4 0.69843
NRGN neurogranin (protein kinase C substrate, RC3) 0.602429
HHAT hedgehog acyltransferase 0.552621
HIST1H2AH histone cluster 1, H2ah 0.52461
MPC2 mitochondrial pyruvate carrier 2 0.52461
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.486425
NT5C2 5'-nucleotidase, cytosolic II 0.464771
AMPD3 adenosine monophosphate deaminase 3 0.449873
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.438544
SDCCAG8 serologically defined colon cancer antigen 8 0.438544
MUSTN1 musculoskeletal, embryonic nuclear protein 1 0.429338
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.429338
EHF ets homologous factor 0.4215
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.4215
CCDC39 coiled-coil domain containing 39 0.403461
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.403461
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.403461
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 0.403461
ZNF804A zinc finger protein 804A 0.368757
SLAMF1 signaling lymphocytic activation molecule family member 1 0.368757
BRD1 bromodomain containing 1 0.368757
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.368757
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.368757
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.368757
VRK2 vaccinia related kinase 2 0.345945
AS3MT arsenite methyltransferase 0.345945
GRIK3 glutamate receptor, ionotropic, kainate 3 0.345945
PKNOX2 PBX/knotted 1 homeobox 2 0.327313
RPP21 ribonuclease P/MRP 21kDa subunit 0.327313
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.327313
GPR137B G protein-coupled receptor 137B 0.311576
RELN reelin 0.311576
PRMT6 protein arginine methyltransferase 6 0.311576
DRD2 dopamine receptor D2 0.311576
HUNK hormonally up-regulated Neu-associated kinase 0.311576
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 0.297866
PTBP2 polypyrimidine tract binding protein 2 0.297866
IL1A interleukin 1, alpha 0.285417
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.285417
ADGRL3 adhesion G protein-coupled receptor L3 0.274608
SNX29 sorting nexin 29 0.264872
PRKCZ protein kinase C, zeta 0.256228
RBM19 RNA binding motif protein 19 0.256228
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.256228
CCDC60 coiled-coil domain containing 60 0.256228
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.256228
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.256228
TCF4 transcription factor 4 0.256228
ZFP90 ZFP90 zinc finger protein 0.256228
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.256228
WWOX WW domain containing oxidoreductase 0.256228
LYZL4 lysozyme-like 4 0.256228
PLAA phospholipase A2-activating protein 0.197766
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.197766
FXR1 fragile X mental retardation, autosomal homolog 1 0.197766
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.197766
ZNF706 zinc finger protein 706 0.197766
CLC Charcot-Leyden crystal galectin 0.197766
PTPRG protein tyrosine phosphatase, receptor type, G 0.197766
CLDN1 claudin 1 0.197766
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.197766
CALN1 calneuron 1 0.197766
AGBL1 ATP/GTP binding protein-like 1 0.197766
MTAP methylthioadenosine phosphorylase 0.197766
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.197766
MYO18B myosin XVIIIB 0.197766
GRID1 glutamate receptor, ionotropic, delta 1 0.197766
PLCB2 phospholipase C, beta 2 0.15771
ITSN2 intersectin 2 0.15771
PID1 phosphotyrosine interaction domain containing 1 0.15771
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.15771
CXCL12 chemokine (C-X-C motif) ligand 12 0.15771
RERE arginine-glutamic acid dipeptide (RE) repeats 0.15771
PCDH20 protocadherin 20 0.15771
RSL24D1 ribosomal L24 domain containing 1 0.15771
IFT88 intraflagellar transport 88 0.15771
CDKN3 cyclin-dependent kinase inhibitor 3 0.15771
METTL15 methyltransferase like 15 0.15771
BMP7 bone morphogenetic protein 7 0.15771
ANXA1 annexin A1 0.15771
SNX19 sorting nexin 19 0.15771
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.15771
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.126165
GPC1 glypican 1 0.126165
RORA RAR-related orphan receptor A 0.126165
ATXN1 ataxin 1 0.126165
PRRC2A proline-rich coiled-coil 2A 0.126165
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.126165
CDC42 cell division cycle 42 0.126165
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.126165
NPAS3 neuronal PAS domain protein 3 0.126165
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.126165
DRAXIN dorsal inhibitory axon guidance protein 0.126165
MSRA methionine sulfoxide reductase A 0.126165
MAST4 microtubule associated serine/threonine kinase family member 4 0.100789
MXRA5 matrix-remodelling associated 5 0.100789
ARL4P ADP-ribosylation factor-like 4 pseudogene 0.100789
TRAF3 TNF receptor-associated factor 3 0.100789
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.100789
LNX2 ligand of numb-protein X 2 0.100789
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.100789
ARHGAP31 Rho GTPase activating protein 31 0.100789
FBXO11 F-box protein 11 0.080593
TNIK TRAF2 and NCK interacting kinase 0.080593
MFAP3 microfibrillar-associated protein 3 0.080593
CNTNAP5 contactin associated protein-like 5 0.080593
SHISA9 shisa family member 9 0.080593
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.080593
KIF26B kinesin family member 26B 0.064973
SH3RF1 SH3 domain containing ring finger 1 0.064973
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.064973
SUCNR1 succinate receptor 1 0.064973
FMR1NB fragile X mental retardation 1 neighbor 0.064973
HABP2 hyaluronan binding protein 2 0.064973
CIART circadian associated repressor of transcription 0.064973
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.052255
SETBP1 SET binding protein 1 0.052255
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.052255
NLRC5 NLR family, CARD domain containing 5 0.052255
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.052255
YLPM1 YLP motif containing 1 0.052255
ZFYVE28 zinc finger, FYVE domain containing 28 0.043246
MMS22L MMS22-like, DNA repair protein 0.043246
ZBED9 zinc finger, BED-type containing 9 0.043246
EBF2 early B-cell factor 2 0.035343