scf ubiquitin ligase complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). (Gene Ontology, GO_0019005)
External Link http://amigo.geneontology.org/amigo/term/GO:0019005
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30 proteins localized to the scf ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCNF cyclin F
CUL1 cullin 1
FBXL15 F-box and leucine-rich repeat protein 15
FBXL19 F-box and leucine-rich repeat protein 19
FBXL2 F-box and leucine-rich repeat protein 2
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene)
FBXL3 F-box and leucine-rich repeat protein 3
FBXL5 F-box and leucine-rich repeat protein 5
FBXL7 F-box and leucine-rich repeat protein 7
FBXO15 F-box protein 15
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO25 F-box protein 25
FBXO27 F-box protein 27
FBXO31 F-box protein 31
FBXO4 F-box protein 4
FBXO44 F-box protein 44
FBXO6 F-box protein 6
FBXO9 F-box protein 9
FBXW11 F-box and WD repeat domain containing 11
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
PARK2 parkin RBR E3 ubiquitin protein ligase
RBX1 ring-box 1, E3 ubiquitin protein ligase
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
USP47 ubiquitin specific peptidase 47