scaffold protein binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes. (Gene Ontology, GO_0097110)
External Link http://amigo.geneontology.org/amigo/term/GO:0097110
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Genes

38 genes performing the scaffold protein binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BIRC8 baculoviral IAP repeat containing 8
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
DLG4 discs, large homolog 4 (Drosophila)
DSP desmoplakin
GJA1 gap junction protein, alpha 1, 43kDa
GRID2 glutamate receptor, ionotropic, delta 2
HOMER1 homer scaffolding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KRT15 keratin 15, type I
KRT18 keratin 18, type I
KRT5 keratin 5, type II
KRT8 keratin 8, type II
LRP4 low density lipoprotein receptor-related protein 4
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NOS1 nitric oxide synthase 1 (neuronal)
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PANX1 pannexin 1
PARK7 parkinson protein 7
PDE4D phosphodiesterase 4D, cAMP-specific
PHF6 PHD finger protein 6
SCN5A sodium channel, voltage gated, type V alpha subunit
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK3 SH3 and multiple ankyrin repeat domains 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
VIM vimentin