sarcoma Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A cell type cancer that has_material_basis_in abnormally proliferating cells derived_from embryonic mesoderm. (Human Disease Ontology, DOID_1115)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0100242
Similar Terms
Downloads & Tools

Genes

92 genes associated with the sarcoma phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANTXR2 anthrax toxin receptor 2
APC adenomatous polyposis coli
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN2 axin 2
BAX BCL2-associated X protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP57 centrosomal protein 57kDa
CHEK2 checkpoint kinase 2
COL1A1 collagen, type I, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCC DCC netrin 1 receptor
DDIT3 DNA-damage-inducible transcript 3
DHCR24 24-dehydrocholesterol reductase
DICER1 dicer 1, ribonuclease type III
EP300 E1A binding protein p300
EWSR1 EWS RNA-binding protein 1
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FGFR3 fibroblast growth factor receptor 3
FH fumarate hydratase
FLCN folliculin
FLNA filamin A, alpha
FOXC2 forkhead box C2
FOXO1 forkhead box O1
FUS FUS RNA binding protein
GNAS GNAS complex locus
HMGA2 high mobility group AT-hook 2
HRAS Harvey rat sarcoma viral oncogene homolog
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLLN killin, p53-regulated DNA replication inhibitor
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT17 keratin 17, type I
LEMD3 LEM domain containing 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEN1 multiple endocrine neoplasia I
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTAP methylthioadenosine phosphorylase
NBN nibrin
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NOTCH3 notch 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PAX3 paired box 3
PAX7 paired box 7
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDGFRL platelet-derived growth factor receptor-like
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCD1 phospholipase C, delta 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PTCH1 patched 1
PTCH2 patched 2
PTEN phosphatase and tensin homolog
PTH1R parathyroid hormone 1 receptor
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD54B RAD54 homolog B (S. cerevisiae)
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RPS19 ribosomal protein S19
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC22A18 solute carrier family 22, member 18
SOS1 son of sevenless homolog 1 (Drosophila)
SPRED1 sprouty-related, EVH1 domain containing 1
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SUFU suppressor of fused homolog (Drosophila)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TFG TRK-fused gene
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1