salbutamol-7376 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the salbutamol-7376 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADGRL1 adhesion G protein-coupled receptor L1
ANXA10 annexin A10
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BCL2A1 BCL2-related protein A1
CALB2 calbindin 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CD247 CD247 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CEP162 centrosomal protein 162kDa
CLCN6 chloride channel, voltage-sensitive 6
COL4A6 collagen, type IV, alpha 6
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CREBZF CREB/ATF bZIP transcription factor
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTH cystathionine gamma-lyase
DCAF11 DDB1 and CUL4 associated factor 11
DFNB31 deafness, autosomal recessive 31
DMBT1 deleted in malignant brain tumors 1
DNAH7 dynein, axonemal, heavy chain 7
DPF3 D4, zinc and double PHD fingers, family 3
DUSP1 dual specificity phosphatase 1
EFNA3 ephrin-A3
EN1 engrailed homeobox 1
EPAS1 endothelial PAS domain protein 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FA2H fatty acid 2-hydroxylase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
HMHA1 histocompatibility (minor) HA-1
HOXA7 homeobox A7
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL1RL1 interleukin 1 receptor-like 1
IL33 interleukin 33
ISG20 interferon stimulated exonuclease gene 20kDa
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD14 potassium channel tetramerization domain containing 14
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LYPD3 LY6/PLAUR domain containing 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
METTL7A methyltransferase like 7A
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
MYBPC3 myosin binding protein C, cardiac
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NPEPL1 aminopeptidase-like 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRF1 nuclear respiratory factor 1
OASL 2'-5'-oligoadenylate synthetase-like
ORC5 origin recognition complex, subunit 5
PAIP2B poly(A) binding protein interacting protein 2B
PDE4D phosphodiesterase 4D, cAMP-specific
PF4 platelet factor 4
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRPH peripherin
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RBMS2 RNA binding motif, single stranded interacting protein 2
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SLC17A2 solute carrier family 17, member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMOX spermine oxidase
SREBF2 sterol regulatory element binding transcription factor 2
STC1 stanniocalcin 1
STRA6 stimulated by retinoic acid 6
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAOK1 TAO kinase 1
TBXA2R thromboxane A2 receptor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF1 transmembrane 4 L six family member 1
TMEM231 transmembrane protein 231
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNPO2 transportin 2
ULK2 unc-51 like autophagy activating kinase 2
ZBTB40 zinc finger and BTB domain containing 40
ZFP36L1 ZFP36 ring finger protein-like 1
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF222 zinc finger protein 222

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADORA2B adenosine A2b receptor
ADRB2 adrenoceptor beta 2, surface
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMIGO2 adhesion molecule with Ig-like domain 2
APLP1 amyloid beta (A4) precursor-like protein 1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BCAS3 breast carcinoma amplified sequence 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC3 baculoviral IAP repeat containing 3
BRWD1 bromodomain and WD repeat domain containing 1
C1ORF159 chromosome 1 open reading frame 159
C3ORF52 chromosome 3 open reading frame 52
C8ORF60 chromosome 8 open reading frame 60
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN15 calpain 15
CCNO cyclin O
CCNT1 cyclin T1
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC10A C-type lectin domain family 10, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CTGF connective tissue growth factor
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP5 dual specificity phosphatase 5
ERF Ets2 repressor factor
ETAA1 Ewing tumor-associated antigen 1
FAM102A family with sequence similarity 102, member A
FAM188A family with sequence similarity 188, member A
FIG4 FIG4 phosphoinositide 5-phosphatase
FJX1 four jointed box 1 (Drosophila)
FSD1 fibronectin type III and SPRY domain containing 1
GBX2 gastrulation brain homeobox 2
GJC1 gap junction protein, gamma 1, 45kDa
HIST1H2AM histone cluster 1, H2am
HIST1H2BJ histone cluster 1, H2bj
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HYAL3 hyaluronoglucosaminidase 3
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JADE3 jade family PHD finger 3
KIRREL kin of IRRE like (Drosophila)
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT15 keratin 15, type I
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEX3C mex-3 RNA binding family member C
MFGE8 milk fat globule-EGF factor 8 protein
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NINJ1 ninjurin 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
NXPH4 neurexophilin 4
OGFRL1 opioid growth factor receptor-like 1
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PLK2 polo-like kinase 2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR16 proline rich 16
PRR7 proline rich 7 (synaptic)
PRSS16 protease, serine, 16 (thymus)
PTX3 pentraxin 3, long
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF2 ring finger protein 2
SCAMP5 secretory carrier membrane protein 5
SCHIP1 schwannomin interacting protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A40 solute carrier family 25, member 40
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMAD7 SMAD family member 7
SMAGP small cell adhesion glycoprotein
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TLR2 toll-like receptor 2
TM7SF2 transmembrane 7 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TRAPPC2 trafficking protein particle complex 2
ZNF180 zinc finger protein 180
ZXDC ZXD family zinc finger C