salbutamol-4700 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the salbutamol-4700 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADM adrenomedullin
AHSP alpha hemoglobin stabilizing protein
AMPD3 adenosine monophosphate deaminase 3
ANGEL2 angel homolog 2 (Drosophila)
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP25 Rho GTPase activating protein 25
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BGN biglycan
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CALB1 calbindin 1, 28kDa
CCDC186 coiled-coil domain containing 186
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CD58 CD58 molecule
CDC14A cell division cycle 14A
CDK18 cyclin-dependent kinase 18
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COPA coatomer protein complex, subunit alpha
CRABP1 cellular retinoic acid binding protein 1
DCAF11 DDB1 and CUL4 associated factor 11
DGKQ diacylglycerol kinase, theta 110kDa
DMXL2 Dmx-like 2
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EVA1B eva-1 homolog B (C. elegans)
EZR ezrin
FAM105A family with sequence similarity 105, member A
FAM66D family with sequence similarity 66, member D
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
FMOD fibromodulin
FNTB farnesyltransferase, CAAX box, beta
GBP2 guanylate binding protein 2, interferon-inducible
GLRX3 glutaredoxin 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOLGA8A golgin A8 family, member A
HIST1H2BL histone cluster 1, H2bl
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HOXA9 homeobox A9
HSF4 heat shock transcription factor 4
IGFBP6 insulin-like growth factor binding protein 6
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLF12 Kruppel-like factor 12
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
LIMK2 LIM domain kinase 2
LPIN1 lipin 1
LPL lipoprotein lipase
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK10 mitogen-activated protein kinase 10
MBD2 methyl-CpG binding domain protein 2
MED25 mediator complex subunit 25
MED28 mediator complex subunit 28
MIER2 mesoderm induction early response 1, family member 2
NFIB nuclear factor I/B
NME5 NME/NM23 family member 5
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ONECUT2 one cut homeobox 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCDHA6 protocadherin alpha 6
PGR progesterone receptor
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLK4 polo-like kinase 4
POU3F2 POU class 3 homeobox 2
PQLC2 PQ loop repeat containing 2
PTCRA pre T-cell antigen receptor alpha
PVR poliovirus receptor
RASA3 RAS p21 protein activator 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBMS2 RNA binding motif, single stranded interacting protein 2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SAP30 Sin3A-associated protein, 30kDa
SFRP4 secreted frizzled-related protein 4
SIRT5 sirtuin 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
TBC1D2B TBC1 domain family, member 2B
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM194A transmembrane protein 194A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
UCN urocortin
VDAC3 voltage-dependent anion channel 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YTHDC2 YTH domain containing 2
ZBTB17 zinc finger and BTB domain containing 17
ZNF24 zinc finger protein 24
ZNF304 zinc finger protein 304
ZNF473 zinc finger protein 473
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ARHGAP4 Rho GTPase activating protein 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF29 chromosome 22 open reading frame 29
C2ORF27A chromosome 2 open reading frame 27A
C7ORF69 chromosome 7 open reading frame 69
CAPG capping protein (actin filament), gelsolin-like
CD79A CD79a molecule, immunoglobulin-associated alpha
CEL carboxyl ester lipase
CENPO centromere protein O
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CRYGC crystallin, gamma C
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DOCK5 dedicator of cytokinesis 5
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EGR3 early growth response 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM155A family with sequence similarity 155, member A
FLCN folliculin
FLJ22184
FRK fyn-related Src family tyrosine kinase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA4 GATA binding protein 4
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPC3 glypican 3
GRTP1 growth hormone regulated TBC protein 1
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPA1L heat shock 70kDa protein 1-like
IFT81 intraflagellar transport 81
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
KLC2 kinesin light chain 2
KLF13 Kruppel-like factor 13
KREMEN2 kringle containing transmembrane protein 2
KRT31 keratin 31, type I
LHX6 LIM homeobox 6
LRRC8E leucine rich repeat containing 8 family, member E
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYRM9 LYR motif containing 9
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MGC12488
MTA2 metastasis associated 1 family, member 2
MUC3B mucin 3B, cell surface associated
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PER3 period circadian clock 3
PLAT plasminogen activator, tissue
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRPH peripherin
PRR14L proline rich 14-like
PRSS53 protease, serine, 53
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRE protein tyrosine phosphatase, receptor type, E
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3D RAB3D, member RAS oncogene family
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF2 ring finger protein 2
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SIK1 salt-inducible kinase 1
SOX3 SRY (sex determining region Y)-box 3
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRYD7 SPRY domain containing 7
SREK1IP1 SREK1-interacting protein 1
TEP1 telomerase-associated protein 1
TLN1 talin 1
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TPK1 thiamin pyrophosphokinase 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
VLDLR very low density lipoprotein receptor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZNF516 zinc finger protein 516
ZNF669 zinc finger protein 669
ZNF675 zinc finger protein 675