ruffle assembly Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. (Gene Ontology, GO_0097178)
External Link http://amigo.geneontology.org/amigo/term/GO:0097178
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Genes

9 genes participating in the ruffle assembly biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AIF1 allograft inflammatory factor 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BAG4 BCL2-associated athanogene 4
DBNL drebrin-like
INPP5K inositol polyphosphate-5-phosphatase K
INPPL1 inositol polyphosphate phosphatase-like 1
MTSS1L metastasis suppressor 1-like
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)