rosiglitazone-6192 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the rosiglitazone-6192 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACACB acetyl-CoA carboxylase beta
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMH anti-Mullerian hormone
APC2 adenomatosis polyposis coli 2
AQP3 aquaporin 3 (Gill blood group)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C8B complement component 8, beta polypeptide
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALD1 caldesmon 1
CAV2 caveolin 2
CCL27 chemokine (C-C motif) ligand 27
CD36 CD36 molecule (thrombospondin receptor)
CD93 CD93 molecule
CELA2A chymotrypsin-like elastase family, member 2A
CHI3L2 chitinase 3-like 2
CHRM4 cholinergic receptor, muscarinic 4
CLCN1 chloride channel, voltage-sensitive 1
COL1A1 collagen, type I, alpha 1
CTNNBIP1 catenin, beta interacting protein 1
CUZD1 CUB and zona pellucida-like domains 1
DMTN dematin actin binding protein
EDNRA endothelin receptor type A
ELOVL2 ELOVL fatty acid elongase 2
FAM212B family with sequence similarity 212, member B
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FHL1 four and a half LIM domains 1
FRMPD1 FERM and PDZ domain containing 1
FZD4 frizzled class receptor 4
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GIPR gastric inhibitory polypeptide receptor
GPR75 G protein-coupled receptor 75
GUCA1A guanylate cyclase activator 1A (retina)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HPCAL4 hippocalcin like 4
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
KLHL11 kelch-like family member 11
KLHL3 kelch-like family member 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LGALS2 lectin, galactoside-binding, soluble, 2
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LINC00472 long intergenic non-protein coding RNA 472
LINC01558 long intergenic non-protein coding RNA 1558
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2 microtubule-associated protein 2
MBD2 methyl-CpG binding domain protein 2
MECOM MDS1 and EVI1 complex locus
MPZL2 myelin protein zero-like 2
MST1L macrophage stimulating 1-like
MTSS1L metastasis suppressor 1-like
NIPAL2 NIPA-like domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NPC1 Niemann-Pick disease, type C1
OCLN occludin
OSBPL10 oxysterol binding protein-like 10
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAIP2B poly(A) binding protein interacting protein 2B
PDC phosducin
PLAC1 placenta-specific 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRAMEF12 PRAME family member 12
PRKCH protein kinase C, eta
PRPF18 pre-mRNA processing factor 18
PTGDR2 prostaglandin D2 receptor 2
PYHIN1 pyrin and HIN domain family, member 1
RASL11B RAS-like, family 11, member B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SCARF1 scavenger receptor class F, member 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3BP2 SH3-domain binding protein 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SPON1 spondin 1, extracellular matrix protein
SPPL2B signal peptide peptidase like 2B
STAB1 stabilin 1
SYT13 synaptotagmin XIII
TBX21 T-box 21
TCP10 t-complex 10
TGM2 transglutaminase 2
THAP9 THAP domain containing 9
TIMELESS timeless circadian clock
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM6SF2 transmembrane 6 superfamily member 2
TMPRSS5 transmembrane protease, serine 5
TMPRSS6 transmembrane protease, serine 6
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRIM3 tripartite motif containing 3
TSHR thyroid stimulating hormone receptor
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP29 ubiquitin specific peptidase 29
ZBTB38 zinc finger and BTB domain containing 38
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZER1 zyg-11 related, cell cycle regulator

decreased expression

Symbol Name
AKTIP AKT interacting protein
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARID5A AT rich interactive domain 5A (MRF1-like)
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG9A autophagy related 9A
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CLSPN claspin
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CTSL cathepsin L
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E4F1 E4F transcription factor 1
EIF5A2 eukaryotic translation initiation factor 5A2
EPHB6 EPH receptor B6
ERO1LB ERO1-like beta (S. cerevisiae)
FBXO22 F-box protein 22
FKBP14 FK506 binding protein 14, 22 kDa
GAA glucosidase, alpha; acid
GAMT guanidinoacetate N-methyltransferase
GLCE glucuronic acid epimerase
GSDMD gasdermin D
HHLA3 HERV-H LTR-associating 3
HIST1H1T histone cluster 1, H1t
ICK intestinal cell (MAK-like) kinase
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT46 intraflagellar transport 46
IFT81 intraflagellar transport 81
IGFBP4 insulin-like growth factor binding protein 4
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INF2 inverted formin, FH2 and WH2 domain containing
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF13B kinesin family member 13B
KIF17 kinesin family member 17
KLF2 Kruppel-like factor 2
KRT8P12 keratin 8 pseudogene 12
LAMB3 laminin, beta 3
LMBR1L limb development membrane protein 1-like
LOC100286895 cell division cycle 27 homolog pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MCRS1 microspherule protein 1
MDM4 MDM4, p53 regulator
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKL2 MKL/myocardin-like 2
MPZ myelin protein zero
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NPIPB3 nuclear pore complex interacting protein family, member B3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OCEL1 occludin/ELL domain containing 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PHC1 polyhomeotic homolog 1 (Drosophila)
POLM polymerase (DNA directed), mu
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFXAP regulatory factor X-associated protein
RIN2 Ras and Rab interactor 2
RNF25 ring finger protein 25
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SGMS1 sphingomyelin synthase 1
SH2D3C SH2 domain containing 3C
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMYD5 SMYD family member 5
SREK1IP1 SREK1-interacting protein 1
TBC1D17 TBC1 domain family, member 17
TCTN1 tectonic family member 1
THAP10 THAP domain containing 10
THBS4 thrombospondin 4
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TPST1 tyrosylprotein sulfotransferase 1
TTC23 tetratricopeptide repeat domain 23
UBXN6 UBX domain protein 6
UNC119 unc-119 homolog (C. elegans)
UPB1 ureidopropionase, beta
USB1 U6 snRNA biogenesis 1
WDR91 WD repeat domain 91
WWC2 WW and C2 domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZNF10 zinc finger protein 10
ZNF222 zinc finger protein 222
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF813 zinc finger protein 813