rosiglitazone-430 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the rosiglitazone-430 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAA2 acetyl-CoA acyltransferase 2
ACSL4 acyl-CoA synthetase long-chain family member 4
ADM2 adrenomedullin 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPTL4 angiopoietin-like 4
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ATP13A3 ATPase type 13A3
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
C20ORF27 chromosome 20 open reading frame 27
C2CD2L C2CD2-like
CBX5 chromobox homolog 5
CD302 CD302 molecule
CDC25A cell division cycle 25A
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIAO1 cytosolic iron-sulfur assembly component 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPE carboxypeptidase E
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRY1 cryptochrome circadian clock 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSN2 casein beta
CYLD cylindromatosis (turban tumor syndrome)
DAXX death-domain associated protein
DMWD dystrophia myotonica, WD repeat containing
DST dystonin
E2F5 E2F transcription factor 5, p130-binding
EFNB3 ephrin-B3
EIF1 eukaryotic translation initiation factor 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EPOR erythropoietin receptor
FA2H fatty acid 2-hydroxylase
FABP4 fatty acid binding protein 4, adipocyte
FCAR Fc fragment of IgA receptor
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
H2AFY2 H2A histone family, member Y2
HUS1 HUS1 checkpoint homolog (S. pombe)
IL1B interleukin 1, beta
INTS6 integrator complex subunit 6
IRS2 insulin receptor substrate 2
ITGB5 integrin, beta 5
ITSN1 intersectin 1 (SH3 domain protein)
JUN jun proto-oncogene
KLHL20 kelch-like family member 20
LPIN1 lipin 1
MAGOHB mago-nashi homolog B (Drosophila)
MED28 mediator complex subunit 28
MED4 mediator complex subunit 4
MOB3B MOB kinase activator 3B
MTF1 metal-regulatory transcription factor 1
MZF1 myeloid zinc finger 1
NOL6 nucleolar protein 6 (RNA-associated)
NPAT nuclear protein, ataxia-telangiectasia locus
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OMD osteomodulin
PALB2 partner and localizer of BRCA2
PC pyruvate carboxylase
PLIN2 perilipin 2
POGZ pogo transposable element with ZNF domain
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POMT2 protein-O-mannosyltransferase 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R17 protein phosphatase 1, regulatory subunit 17
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKCD protein kinase C, delta
PRPF39 pre-mRNA processing factor 39
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSPH phosphoserine phosphatase
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPRT protein tyrosine phosphatase, receptor type, T
RAD54L RAD54-like (S. cerevisiae)
RBKS ribokinase
RFPL2 ret finger protein-like 2
RHOB ras homolog family member B
RNF141 ring finger protein 141
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEC23B Sec23 homolog B (S. cerevisiae)
SIRT6 sirtuin 6
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC45A2 solute carrier family 45, member 2
SLMO2 slowmo homolog 2 (Drosophila)
SMAD6 SMAD family member 6
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPRED2 sprouty-related, EVH1 domain containing 2
STC2 stanniocalcin 2
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TGFA transforming growth factor, alpha
TGM2 transglutaminase 2
TMPRSS5 transmembrane protease, serine 5
TMSB15A thymosin beta 15a
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM58 tripartite motif containing 58
TUBA4B tubulin, alpha 4b
TWISTNB TWIST neighbor
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACVRL1 activin A receptor type II-like 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AHDC1 AT hook, DNA binding motif, containing 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASIP agouti signaling protein
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CA5A carbonic anhydrase VA, mitochondrial
CCDC71 coiled-coil domain containing 71
CD1A CD1a molecule
CD5 CD5 molecule
CFAP70 cilia and flagella associated protein 70
CHRM4 cholinergic receptor, muscarinic 4
COL5A2 collagen, type V, alpha 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRYGD crystallin, gamma D
CTGF connective tissue growth factor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EGLN3 egl-9 family hypoxia-inducible factor 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM153A family with sequence similarity 153, member A
FAM155A family with sequence similarity 155, member A
FAM188A family with sequence similarity 188, member A
FOXD1 forkhead box D1
FZD8 frizzled class receptor 8
GAL3ST4 galactose-3-O-sulfotransferase 4
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALR3 galanin receptor 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBAP1 glucosidase, beta, acid pseudogene 1
GJA9 gap junction protein, alpha 9, 59kDa
GLDC glycine dehydrogenase (decarboxylating)
GSDMD gasdermin D
HIRIP3 HIRA interacting protein 3
HIST1H2BI histone cluster 1, H2bi
HIST1H4J histone cluster 1, H4j
HMG20A high mobility group 20A
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFAP3 kinesin-associated protein 3
KRT15 keratin 15, type I
LGALS13 lectin, galactoside-binding, soluble, 13
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOC441601 septin 7 pseudogene
LYPD3 LY6/PLAUR domain containing 3
MAGEA3 melanoma antigen family A3
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MICALL2 MICAL-like 2
MLN motilin
MSRB1 methionine sulfoxide reductase B1
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NEUROD4 neuronal differentiation 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ONECUT2 one cut homeobox 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHB6 protocadherin beta 6
PFAS phosphoribosylformylglycinamidine synthase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PKD2L1 polycystic kidney disease 2-like 1
PLK2 polo-like kinase 2
PPARG peroxisome proliferator-activated receptor gamma
PPP4C protein phosphatase 4, catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PTX3 pentraxin 3, long
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
S100PBP S100P binding protein
SFTPA2 surfactant protein A2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIX1 SIX homeobox 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMA4 glucuronidase, beta pseudogene
STARD8 StAR-related lipid transfer (START) domain containing 8
STAT5A signal transducer and activator of transcription 5A
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TET3 tet methylcytosine dioxygenase 3
TEX13B testis expressed 13B
TMEM156 transmembrane protein 156
TMEM180 transmembrane protein 180
TMEM204 transmembrane protein 204
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
VPS9D1 VPS9 domain containing 1
WDR5B WD repeat domain 5B
ZMYM3 zinc finger, MYM-type 3
ZNF385D zinc finger protein 385D
ZNF654 zinc finger protein 654