rosiglitazone-1071 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the rosiglitazone-1071 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGA aspartylglucosaminidase
APP amyloid beta (A4) precursor protein
ARHGAP10 Rho GTPase activating protein 10
BAX BCL2-associated X protein
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF76 chromosome 10 open reading frame 76
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CDK16 cyclin-dependent kinase 16
CEP290 centrosomal protein 290kDa
CEP57 centrosomal protein 57kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHPF2 chondroitin polymerizing factor 2
CNPY3 canopy FGF signaling regulator 3
CSAD cysteine sulfinic acid decarboxylase
CSNK1E casein kinase 1, epsilon
CSNK1G2 casein kinase 1, gamma 2
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DOCK9 dedicator of cytokinesis 9
DUSP4 dual specificity phosphatase 4
ETHE1 ethylmalonic encephalopathy 1
FADS1 fatty acid desaturase 1
FAM134B family with sequence similarity 134, member B
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HDAC6 histone deacetylase 6
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JUNB jun B proto-oncogene
KDM4A lysine (K)-specific demethylase 4A
KLHL36 kelch-like family member 36
KLK6 kallikrein-related peptidase 6
KPTN kaptin (actin binding protein)
KRIT1 KRIT1, ankyrin repeat containing
LAMB1 laminin, beta 1
LARS2 leucyl-tRNA synthetase 2, mitochondrial
MAP4 microtubule-associated protein 4
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL17 mitochondrial ribosomal protein L17
MSH3 mutS homolog 3
NCKAP1 NCK-associated protein 1
NDRG4 NDRG family member 4
NMT1 N-myristoyltransferase 1
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPM3 nucleophosmin/nucleoplasmin 3
NSUN5P2 NOP2/Sun domain family, member 5 pseudogene 2
NUP210 nucleoporin 210kDa
OXTR oxytocin receptor
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSEN2 presenilin 2
PTBP3 polypyrimidine tract binding protein 3
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRU protein tyrosine phosphatase, receptor type, U
PXN paxillin
PYCR1 pyrroline-5-carboxylate reductase 1
RAB5C RAB5C, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RALGDS ral guanine nucleotide dissociation stimulator
RBM3 RNA binding motif (RNP1, RRM) protein 3
RNF14 ring finger protein 14
RPS2 ribosomal protein S2
RYK receptor-like tyrosine kinase
S100A4 S100 calcium binding protein A4
SLC2A4RG SLC2A4 regulator
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SPATA2L spermatogenesis associated 2-like
SRRM2 serine/arginine repetitive matrix 2
SS18 synovial sarcoma translocation, chromosome 18
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYCP2 synaptonemal complex protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL3 transducin (beta)-like 3
TCF3 transcription factor 3
TCOF1 Treacher Collins-Franceschetti syndrome 1
TDRD3 tudor domain containing 3
TLE3 transducin-like enhancer of split 3
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC10 trafficking protein particle complex 10
TRAPPC12 trafficking protein particle complex 12
TSKU tsukushi, small leucine rich proteoglycan
UBQLN4 ubiquilin 4
VWA8 von Willebrand factor A domain containing 8
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR46 WD repeat domain 46
WDR48 WD repeat domain 48
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD4 abhydrolase domain containing 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRL2 adhesion G protein-coupled receptor L2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATP7B ATPase, Cu++ transporting, beta polypeptide
BBC3 BCL2 binding component 3
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNE1 cyclin E1
CDKN2AIP CDKN2A interacting protein
CENPC centromere protein C
CGREF1 cell growth regulator with EF-hand domain 1
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CTSC cathepsin C
CTSV cathepsin V
DDRGK1 DDRGK domain containing 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
EFCAB2 EF-hand calcium binding domain 2
EPPK1 epiplakin 1
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FGD6 FYVE, RhoGEF and PH domain containing 6
FPGS folylpolyglutamate synthase
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALT galactose-1-phosphate uridylyltransferase
GFOD1 glucose-fructose oxidoreductase domain containing 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GTPBP2 GTP binding protein 2
HPS6 Hermansky-Pudlak syndrome 6
ICK intestinal cell (MAK-like) kinase
IRF2 interferon regulatory factor 2
IRF7 interferon regulatory factor 7
KDM5C lysine (K)-specific demethylase 5C
KRT13 keratin 13, type I
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAP9 microtubule-associated protein 9
MARC1 mitochondrial amidoxime reducing component 1
MINPP1 multiple inositol-polyphosphate phosphatase 1
MMD monocyte to macrophage differentiation-associated
MPI mannose phosphate isomerase
NAP1L2 nucleosome assembly protein 1-like 2
NUP62CL nucleoporin 62kDa C-terminal like
PARG poly (ADP-ribose) glycohydrolase
PMP22 peripheral myelin protein 22
PNRC1 proline-rich nuclear receptor coactivator 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PP14571 uncharacterized LOC100130449
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF170 ring finger protein 170
SCML1 sex comb on midleg-like 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SECISBP2L SECIS binding protein 2-like
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIK1 salt-inducible kinase 1
SLC25A40 solute carrier family 25, member 40
SLC38A10 solute carrier family 38, member 10
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAP29 synaptosomal-associated protein, 29kDa
SP1 Sp1 transcription factor
STX5 syntaxin 5
TES testin LIM domain protein
TESK1 testis-specific kinase 1
TET3 tet methylcytosine dioxygenase 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TMEM183A transmembrane protein 183A
TPRA1 transmembrane protein, adipocyte asscociated 1
TPST2 tyrosylprotein sulfotransferase 2
TRAF5 TNF receptor-associated factor 5
TRAPPC11 trafficking protein particle complex 11
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBIAD1 UbiA prenyltransferase domain containing 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC50 unc-50 homolog (C. elegans)
URM1 ubiquitin related modifier 1
VASP vasodilator-stimulated phosphoprotein
WDR44 WD repeat domain 44
WDR60 WD repeat domain 60
ZC3H3 zinc finger CCCH-type containing 3
ZMAT5 zinc finger, matrin-type 5
ZMYM3 zinc finger, MYM-type 3
ZNF32 zinc finger protein 32
ZNF468 zinc finger protein 468
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2