rolipram-6449 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the rolipram-6449 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADORA1 adenosine A1 receptor
AGBL2 ATP/GTP binding protein-like 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANXA2P3 annexin A2 pseudogene 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BGN biglycan
C17ORF59 chromosome 17 open reading frame 59
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC134 coiled-coil domain containing 134
CCPG1 cell cycle progression 1
CD47 CD47 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDY1 chromodomain protein, Y-linked, 1
CELA2A chymotrypsin-like elastase family, member 2A
CEP164 centrosomal protein 164kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRND cholinergic receptor, nicotinic, delta (muscle)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL9A3 collagen, type IX, alpha 3
CRHR2 corticotropin releasing hormone receptor 2
CTH cystathionine gamma-lyase
CTIF CBP80/20-dependent translation initiation factor
CXCR6 chemokine (C-X-C motif) receptor 6
DMXL2 Dmx-like 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPYC epiphycan
ERN1 endoplasmic reticulum to nucleus signaling 1
FABP3 fatty acid binding protein 3, muscle and heart
FKBP10 FK506 binding protein 10, 65 kDa
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GLT8D2 glycosyltransferase 8 domain containing 2
GRIP2 glutamate receptor interacting protein 2
GSTA1 glutathione S-transferase alpha 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HAP1 huntingtin-associated protein 1
HGD homogentisate 1,2-dioxygenase
HIST1H3E histone cluster 1, H3e
HLA-DOA major histocompatibility complex, class II, DO alpha
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL1RN interleukin 1 receptor antagonist
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRT15 keratin 15, type I
LDB3 LIM domain binding 3
LIMK1 LIM domain kinase 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MST1 macrophage stimulating 1
MYO1B myosin IB
NCOR2 nuclear receptor corepressor 2
NEUROD4 neuronal differentiation 4
NF1 neurofibromin 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PCDHA6 protocadherin alpha 6
PCSK6 proprotein convertase subtilisin/kexin type 6
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLCL2 phospholipase C-like 2
PML promyelocytic leukemia
POPDC3 popeye domain containing 3
POU2F2 POU class 2 homeobox 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM10 PR domain containing 10
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
QKI QKI, KH domain containing, RNA binding
RAD54B RAD54 homolog B (S. cerevisiae)
RALGDS ral guanine nucleotide dissociation stimulator
REC8 REC8 meiotic recombination protein
RGS6 regulator of G-protein signaling 6
RHBG Rh family, B glycoprotein (gene/pseudogene)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMAD6 SMAD family member 6
SPTBN1 spectrin, beta, non-erythrocytic 1
TEX40 testis expressed 40
TLDC1 TBC/LysM-associated domain containing 1
TMEM259 transmembrane protein 259
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TSHR thyroid stimulating hormone receptor
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YOD1 YOD1 deubiquitinase
ZNF532 zinc finger protein 532
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AFF4 AF4/FMR2 family, member 4
AMH anti-Mullerian hormone
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOD apolipoprotein D
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX2 armadillo repeat containing, X-linked 2
C1ORF21 chromosome 1 open reading frame 21
C5AR2 complement component 5a receptor 2
CAMKMT calmodulin-lysine N-methyltransferase
CCDC132 coiled-coil domain containing 132
CEP85 centrosomal protein 85kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCA1 chloride channel accessory 1
CLDN17 claudin 17
CLIC2 chloride intracellular channel 2
CXADR coxsackie virus and adenovirus receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
GALK1 galactokinase 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC3 glypican 3
GPHN gephyrin
HIST1H1E histone cluster 1, H1e
HIST1H2AI histone cluster 1, H2ai
HIST1H4D histone cluster 1, H4d
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL12RB1 interleukin 12 receptor, beta 1
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KLF7 Kruppel-like factor 7 (ubiquitous)
LINC00597 long intergenic non-protein coding RNA 597
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRP5L low density lipoprotein receptor-related protein 5-like
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
MMP9 matrix metallopeptidase 9
MRPL44 mitochondrial ribosomal protein L44
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
NXPH4 neurexophilin 4
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEX26 peroxisomal biogenesis factor 26
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS50 protease, serine, 50
RAB23 RAB23, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A2 S100 calcium binding protein A2
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP5 secreted frizzled-related protein 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA21 small nucleolar RNA, H/ACA box 21
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TCHH trichohyalin
TESC tescalcin
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOM1 target of myb1 (chicken)
TPST1 tyrosylprotein sulfotransferase 1
TRABD TraB domain containing
TRAF2 TNF receptor-associated factor 2
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF204P zinc finger protein 204, pseudogene
ZNF350 zinc finger protein 350
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862