rocky mountain spotted fever Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, and has_symptom maculopapular rash progressing into papular or petechial rash. (Human Disease Ontology, DOID_0050052)
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Genes

47 genes co-occuring with the disease rocky mountain spotted fever in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AFF2 AF4/FMR2 family, member 2 1.5569
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.782298
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.694301
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.642615
SCAI suppressor of cancer cell invasion 0.630027
CLDN11 claudin 11 0.606543
F3 coagulation factor III (thromboplastin, tissue factor) 0.573828
HMOX1 heme oxygenase 1 0.538893
CXCL9 chemokine (C-X-C motif) ligand 9 0.513417
CXCR3 chemokine (C-X-C motif) receptor 3 0.484364
PFN4 profilin family, member 4 0.4443
LPO lactoperoxidase 0.432646
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.42739
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.42739
VASP vasodilator-stimulated phosphoprotein 0.42139
ATR ATR serine/threonine kinase 0.392257
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.391513
G6PD glucose-6-phosphate dehydrogenase 0.388166
PFN1 profilin 1 0.386679
PFN2 profilin 2 0.378514
TES testin LIM domain protein 0.377031
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.36187
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.357077
CCL2 chemokine (C-C motif) ligand 2 0.351187
PLG plasminogen 0.347879
CXCL10 chemokine (C-X-C motif) ligand 10 0.328834
PXN paxillin 0.321909
AVP arginine vasopressin 0.318635
VCL vinculin 0.308842
TSPO translocator protein (18kDa) 0.299452
MMP12 matrix metallopeptidase 12 0.287235
CS citrate synthase 0.28616
DIABLO diablo, IAP-binding mitochondrial protein 0.279011
PLAT plasminogen activator, tissue 0.263014
PAH phenylalanine hydroxylase 0.260891
EZR ezrin 0.25983
KNG1 kininogen 1 0.230409
F12 coagulation factor XII (Hageman factor) 0.222136
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.219398
LYZ lysozyme 0.216332
CXCL8 chemokine (C-X-C motif) ligand 8 0.212608
CD68 CD68 molecule 0.199356
TPM1 tropomyosin 1 (alpha) 0.192344
CD4 CD4 molecule 0.185612
DNAH8 dynein, axonemal, heavy chain 8 0.165001
RARA retinoic acid receptor, alpha 0.164571
F8 coagulation factor VIII, procoagulant component 0.161716